Mice plasma fibrinogen consumption by thrombin-like enzyme present in rattlesnake venom from the North-East region of Argentina

Medicina

Volumn 64, Issue 6, 2004, Pages 509-517

  Maruñak, Silvana L ^a   Acosta de Pérez, Ofelia C ^a   Leiva, Laura C ^a   Ruiz, Raquel M ^a   Aguirre, Maria V ^a   Teibler, Pamela ^a  

^a UNIVERSIDAD NACIONAL DEL NORDESTE   (Argentina)

Author keywords

Coagulation; Crotalus durissus terrificus; North East Argentina; Thrombin like; Venom

Indexed keywords

COAGULASE; FIBRINOGEN; SNAKE VENOM; THROMBIN;

AFFINITY CHROMATOGRAPHY; ANIMAL BEHAVIOR; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARGENTINA; ARTICLE; CONTROLLED STUDY; DISSEMINATED INTRAVASCULAR CLOTTING; ENZYME ACTIVITY; ENZYME ISOLATION; ENZYME SUBSTRATE; FIBRINOGEN BLOOD LEVEL; GEL FILTRATION CHROMATOGRAPHY; HEART MUSCLE; HISTOPATHOLOGY; HYDROLYSIS; INOCULATION; LIVER; LUNG PARENCHYMA; MOLECULAR WEIGHT; MOUSE; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS;

ANIMALS; ARGENTINA; COAGULANTS; CROTALID VENOMS; CROTALUS; FEMALE; FIBRINOGEN; LIVER; LUNG; MALE; MICE; THROMBIN;

EID: 12344271874     PISSN: 00257680     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (23)

1. Mellamby J. The coagulation of blood. II. The action of snake venoms, peptone and leach extract. J Physiol 1909; 38: 441-503.
2. Seegers WH, Ouyang C. Snake venoms and blood coagulation. In: Lee CY, (ed). Snake venom handbook of experimental pharmacology, Saint Louis: Sigma Chemical, 1991, p. 684-700.
3. Stocker K. Defibrinogenation with thrombin-like snake venom enzymes. Handbook of Farmacology 1978; 46: 451-84.
4. Markland FS Jr, Damus PS. Purification and properties of a thrombin-tike enzyme from the venom of Crotalus adamanteus (Eastem Diamondback rattlesnake). J Biol Chem 1971; 246: 6460-73.
5. Raw I, Rocha MC, Kamiguti AS. Isolation and characterization of a thrombin-like erizyme from the venom of Crotalus durissus terrificus. Braz J Med Biol Res 1986, 19: 333-8.
6. Smolka MB, Marangoni S, Oliveira B, Novello JC. Purification and partial characterization of a thrombin-like enzyme, balterobin, from the venom of Bothrops altematus. Toxicon 1998; 36: 1059-63.
7. Stocker K F. Snake venom proteins affecting hemostasis and fibrinolysis. In: Stocker KF (ed). Medical Use of Snake Venom Proteins. Boston, USA: CRO Press 1990, p 97-9.
8. Nahas L, Denson KWE, Mac Farlane RG. A study of the coagulant action of eight snake venoms. Thromb Diath Haemorrh 1964; 12: 355-67.
9. Alexander G, Grothussen J, Zepeda H, Schwartzman R J. Gyroxin, a toxin from the venom of Crotalus durissus temficus, is a thrombin-like enzyme. Toxicon 1988; 26: 953-60.
10. Cohn MI, Cohn M. Barrel rotation induced by somatostatin in the non-lesioned rat. Brain Res 1975; 96: 139-41.
11. Barrabin H, Martiarena JI, Vidal JC, Barno A. Isolation and characterizaation of gyroxin from Crotalus durissus terrificus venom. In: Rosemberg P. (Ed). Toxins: Animals, Plant and Microbial. New York: Pergamon 1978, p. 113-4.
12. Cavinato R.A, Remold H, Kipnis TL. Purification and variability in thrombin-like activity of Bothrops atrox venom from different geographic regions. Toxicon 1998; 36: 257-67.
13. Word Health Organization (WHO) 23° Informe Técnico de Patrones Biológicos, Publicación N° 37. 1971, Ginebra.
14. Gutiérrez J M, Chaves E, Bolaños R. Comparative study of venoms of newborn and adult specimens of Bothrops asper. 1980. Rev Biol Trop 228: 341-51.
15. Esteso SC. Ofidismo en la República Argentina. Edit Arpon, Córdoba, 1985, p.70-71.
16. Camillo MAP, Arruda Paes PC, Troncone LRP, Rogero JR. Gyroxin fails to modify in vitro release of labelles dopamine and acetylcholine from rat and mouse striatal tissue. Toxicon 2001; 39: 843-53.
17. Laemmli UK. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970; 227: 680-5.
18. Lundblad RL, Kingdon HS, Mann KG. Thrombine. Methods Enzymol 1976; 45: 685-50.
19. Clauss VA. Gerinnungsphysiologishe schnellmethode zur bestimmung des fibrinogens. Acta Haematol 1957; 17: 237-46.
20. Assakura MT, Reichi A P, Mandelbaum FR. Isolation and characterization of five fibrin(ogeno)lytic enzymes from the venom of Philodryas olfersii (green snake). Toxicon 1992; 32: 819-31.
21. Rojas G, Gutiérrez JM, Gené JA, Gómez M, Cerdas L. Neutralización de las actividades tóxicas y enzimá ticas de cuatro venenos de serpientes de Guatemala y Honduras por el antiveneno polivalente producido en Costa Rica. Rev Biol Trop 1987; 35: 59-67
22. Seki C, Vidal JC, Barrio A. Purification of giroxin from a south American rattlesnake (Crotalus durissus terrificus) venom. Toxicon 1980; 18: 235-47.
23. Gené JA, Roy A, Rojas G, Gutiérrez JM and Cerdas L. Comparative study on coagulant, defibrinating, fibrinolytic and fibrinogenolytic activities of Costa Rican crotaline snake venoms and their neutralization by a polyvalent antivenom. Toxicon 1989; 27: 841-8.