Molecular (and functional) imaging of articular cartilage

Journal of Musculoskeletal Neuronal Interactions

Volumn 4, Issue 4, 2004, Pages 365-368

  Gray, Martha L ^a,b,d   Burstein, D ^a,c  

^a HARVARD MIT DIVISION OF HEALTH SCIENCES AND TECHNOLOGY   (United States)

^b New England Baptist Bone Jt Inst   (United States)

^c BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^d NONE   (United States)

Author keywords

Arthritis; Cartilage; Glycosaminoglycan; Imaging; MRI

Indexed keywords

COLLAGEN; GLYCOSAMINOGLYCAN; WATER;

ANISOTROPY; ARTICULAR CARTILAGE; BIOCHEMISTRY; BIOPHYSICS; CHEMICAL STRUCTURE; CHONDROPATHY; CORRELATION ANALYSIS; FUNCTIONAL ASSESSMENT; HISTOPATHOLOGY; HUMAN; MACROMOLECULE; MICROSCOPY; MOLECULAR IMAGING; MORPHOLOGY; NUCLEAR MAGNETIC RESONANCE IMAGING; QUANTITATIVE ANALYSIS; REVIEW; SENSITIVITY AND SPECIFICITY; WATER CONTENT;

BIOCHEMISTRY; BODY WATER; CARTILAGE, ARTICULAR; CHEMISTRY, ANALYTICAL; COLLAGEN; GLYCOSAMINOGLYCANS; HUMANS; MACROMOLECULAR SUBSTANCES; MAGNETIC RESONANCE IMAGING;

EID: 12344264954     PISSN: 11087161     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (69)

1. Hohe J, Faber S, Stammberger T, Reiser M, Englmeier KH, Eckstein F. A technique for 3D in vivo quantification of proton density and magnetization transfer co-efficients of knee joint cartilage. Osteoarthritis Cartilage 2000; 8:426-433.
2. Dardzinski BJ, Mosher TJ, Li S, Van Slyke MA, Smith MB. Spatial variation of T2 in human articular cartilage. Radiology 1997; 205: 546-550.
3. Gruder W, Wagner M, Werner A. MR-microscopic visualization of anisotropic internal cartilage structure using the magic angle technique. Magn Reson Med 1998; 39:376-382.
4. Xia Y. Relaxation anisotrophy in cartilage by NMR microscopy (μMRI) at 14-microm resolution. Magn Reson Med 1998; 39:941-949.
5. Goodwin DW, Wadghiri YZ, Dunn JF. Micro-imaging or articular cartilage: T2, proton density, and the magic angle effect. Acad Radiol 1998; 5:790-798.
6. Foster JE, Maciewicz RA, Aberner J, Dieppe PA, Freemont AJ, Ken MC, Watt I, Waterton JC. Structural periodicity in human articular cartilage: comparison between magnetic resonance imaging and histological findings. Osteoarthritis Cartilage 1999; 7:480-485.
7. Xia Y. Magic angle effect in magnetic resonance imaging of articular cartilage: a review. Invest Radiol 2000; 35:602-621.
8. Xia Y, Moody JB, Burton-Wurster N, Lust G. Quantitative in situ correlation between microscopic MRI and polarized light microscopy studies of articular cartilage. Osteoarthritis Cartilage 2001; 9:393-406.
9. Granot J. Sodium imaging of human body organs and extremities in vivo. Radiology 1988; 167:547-550.
10. Lesperance LM, Gray ML, Burstein D. Determination of fixed charge density in cartilage using nuclear magnetic resonance. J Orthop Res 1992; 10:1-13.
11. Jelicks LA, Paul PK, O'Byrne E, Gupta RK. Hydrogen-1, sodium-23, and carbon-13 MR spectroscopy of cartilage degradation in vitro. J Magn Reson Imaging 1993; 3:565-568.
12. Bashir A. Sodium NMR relaxation parameters in cartilage: implications for MR imaging. Electrical engineering. Massachusetts Institute of Technology, Cambridge; 1995:134.
13. Bashir A, Gray ML, Burstein D. Gd-DTPA2-as a measure of cartilage degradation. Magn Reson Med 1996; 36:665-673.
14. Bashir A, Gray ML, Boutin RD, Burstein D. Glycosaminoglycan in articular cartilage: in vivo assessment with delayed Gd(DTPA)(2-)-enhanced MR imaging. Radiology 1997; 205:551-558.
15. Insko EK, Reddy R, Leigh JS. High resolution, short echo time sodium imaging of articular cartilage. J Magn Reson Imaging 1997; 7:1056-1059.
16. Reddy R, Insko EK, Noyszewski EA, Dandora R, Kneeland JB, Leigh JS. Sodium MRI of human articular cartilage in vivo. Magn Reson Med 1998; 39:697-701.
17. Allen RG, Burstein D, Gray ML. Monitoring glycosaminoglycan replenishment in cartilage explants with gadolinium-enhanced magnetic resonance imaging. J Orthop Res 1999; 17:430-436.
18. Bashir A, Gray ML, Hartke J, Burstein D. Non-destructive imaging of human cartilage glycosaminoglycan concentration by MRI. Magn Reson Med 1999; 41:857-865.
19. Regatte RR, Kaufman JH, Noyszewski EA, Reddy R. Sodium and proton MR properties of cartilage during compression. J Magn Reson Imaging 1999; 10:961-967.
20. Trattnig S, Mlynarik V, Breitenseher M, Huber M, Zembsch A, Rand T, Imhof H. MRI visualization of proteoglycan depletion in articular cartilage via intravenous administration of Gd-DTPA. Magn Reson Imaging 1999; 17:577-583.
21. Shapiro EM, Borthakur A, Dandora R, Kriss A, Leigh JS, Reddy R. Sodium visibility and quantitation in intact bovine articular cartilage using high field (23)Na MRI and MRS. J Magn Reson 2000; 142:24-31.
22. Nieminen MT, Rieppo J, Silvennoinen J, Toyras J, Hakumaki JM, Hyttinen MM, Helminen HJ, Jurvelin JS. Spatial assessment of articular cartilage proteoglycans with Gd-DTPA-enhanced T1 imaging. Magn Reson Med 2002; 48:640-864.
23. Nissi MJ, Toyras J, Laasanen MS Rieppo J, Saarakkala S, Lappalainen R, Jurvelin JS, Nieminen MT. Proteoglycan and collagen sensitive MRI evaluation of normal and degenerated articular cartilage. J Orthop Res 2004; 22:557-564.
24. Weidenbaum M, Foster RJ, Best BA, Saed-Nejad F, Nickoloff E, Newhouse J, Ratcliffe A, Mow VC. Correlating magnetic resonance imaging with the biochemical content of the normal human intervertebral disc. J Orthop Res 1992; 10:552-561.
25. Gahunia HK, Lemaire C, Babyn PS, Cross AR, Kessler MJ, Pritzker KP. Osteoarthritis in rhesus macaque knee joint: quantitative magnetic resonance imaging tissue characterization of articular cartilage. J Rheumatol 1995; 22:1747-1756.
26. Antoniou J, Pike GB, Steffen T, Baramki H, Poole AR, Aebi M, Alini M. Quantitative magnetic resonance imaging in the assessment of degenerative disc disease. Magn Reson Med 1998; 40:900-9007.
27. Fragonas E, Mlynarik V, Jellus V, Micali F, Piras A, Toffanin R, Rizzon R, Vittur F. Correlation between biochemical composition and magnetic resonance appearance of articular cartilage. Osteoarthritis Cartilage 1998; 6:24-32.
28. Goodwin DW, Wadghiri YZ, Dunn JF. Micro-imaging of articular cartilage: T2, proton density, and the magic angle effect. Acad Radiol 1998; 5:790-798.
29. Burstein D, Bashir A, Gray ML. MRI techniques in early stages of cartilage disease. Invest Radiol 2000; 35:622-638.
30. Lusse S, Claassen H, Gehrke T, Hassenpflug J, Schunke M, Heller M. Gluer CC. Evaluation of water content by spatially resolved transverse relaxation times of human articular cartilage. Magn Reson Imaging 2000; 18:423-430.
31. Nieminen MT, Toyras J, Rieppo J, Hakumaki JM, Silvennoinen J, Helminen HJ, Jurvelin JS. Quantitative MR microscopy of enzymatically degraded articular cartilage. Magn Reson Med 2000; 43:676-681.
32. Nieminen MT, Rieppo J, Toyras J, Hakumaki JM, Silvennoinen J, Hyttinen MM, Helminen HJ, Jurvelin JS. T2 relaxation reveals spatial collagen architecture in articular cartilage: a comparative quantitative MRI and polarized light microscopic study. Magn Reson Med 2001; 46:487-934.
33. Toffanin R, Mlynarik V, Russo S, Szomolanyi P, Piras A, Vittur F. Proteoglycan depletion and magnetic resonance parameters of articular cartilage. Arch Biochem Biophys 2001; 390:235-242.
34. Watrin A, Ruaud JP, Olivier PT, Guingamp NC, Gonord PD, Netter PA, Blum AG, Guillot GM, Gillet PM, Loeuille DH. T2 mapping of rat patellar cartilage. Radiology 2001; 219:395-402.
35. Menezes NM, Gray ML, Hartke JR, Burstein D. T2 and T1rho MRI in articular cartilage systems. Magn Reson Med 2004; 51:503-509.
36. Nissi MJ, Toyras J, Laasanen MS Rieppo J, Saarakkala S, Lappalainen R, Jurvelin JS, Nieminen MT. Proteoglycan and collagen sensitive MRI evaluation of normal and degenerated articular cartilage. J Orthop Res 2004; 22:557-564.
37. Kim DK, Ceckler TL, Hascall VC, Calabro A, Balaban RS. Analysis of water-macromolecule proton magnetization transfer in articular cartilage. Magn Reson Med 1993; 29:211-215.
38. Gray ML, Burstein D, Lesperance LM, Gehrke L. Magnetization transfer in cartilage and its constituent macromolecules. Magn Reson Med 1995; 34:319-325.
39. Seo GS, Aoki J, Moriya H, Karakida O, Sone S, Hidaka H, Katsuyama T. Hyaline cartilage: in vivo and in vitro assessment with magnetization transfer imaging. Radiology 1996; 201: 525-530.
40. Wachsmuth L, Juretschke HP, Raiss RX. Can magnetization transfer magnetic resonance imaging follow proteoglycan depletion in articular cartilage? MAGMA 1997; 5:71-78.
41. Antoniou J, Pike GB, Steffen T, Baramki H, Poole AR, Aebi M, Alini M. Quantitative magnetic resonance imaging in the assessment of degenerative disc disease. Magn Reson Med 1998; 40:900-9007.
42. Bageac AC, Gray ML, Zhang M, Poole AR, Burstein D. Development of an MRI surrogate for immunohistochemical staining of collagen damage in cartilage. 5th International Conference on Magnetic Resonance Microscopy, Heidelberg, Germany; 1999.
43. Burstein D, Bashir A, Gray ML. MRI techniques in early stages of cartilage disease. Invest Radiol 2000; 35:622-638.
44. Hohe J, Faber S, Stammberger T, Reiser M, Englmeier KH, Eckstein F. A technique for 3D in vivo quantification of proton density and magnetization transfer co-efficients of knee joint cartilage. Osteoarthritis Cartilage 2000; 8:426-433.
45. Potter K, Butler JJ, Horton WE, Spencer RG. Response of engineered cartilage, tissue to biochemical agents as studied by proton magnetic resonance microscopy. Arthritis Rheum 2000; 43:1580-1590.
46. Toffanin R, Mlynarik V, Russo S, Szomolanyi P, Piras A, Vittur F. Proteoglycan depletion and magnetic resonance parameters of articular cartilage. Arch Biochem Biophys 2001; 390:235-242.
47. Laurent D, Wasvary J, O'Byrne E, Rudin M. In vivo qualitative assessments of articular cartilage in the rabbit knee with high-resolution MRI at 3 T. Magn Reson Med 2003; 50:541-549.
48. Duvvuri U, Reddy R, Patel SD, Kaufman JH, Kneeland JB, Leigh JS. T1rho-relaxation in articular cartilage: effects of enzymatic degradation. Magn Reson Med 1997; 38:863-867.
49. Mlynarik,V, Trattnig S, Huber M, Zembsch A, Imhof H. The role of relaxation times in monitoring proteoglycan depletion in articular cartilage. J Magn Reson Imaging 1999; 10:497-502.
50. Duvvuri U, Charagundla SR, Kudchodkar SB, Kaufman JH, Kneeland JB, Rizi R, Leigh JS, Reddy R. Human knee: in vivo t1(rho)-weighted MR imaging at 1.5 t preliminary experience. Radiology 2001; 220:822-826.
51. Regatte RR, Akella SV, Borthakur A, Kneeland JB, Reddy R. Proteoglycan depletion-induced changes in transverse relaxation maps of cartilage: comparison of T2 and T1rho. Acad Radiol 2002; 9:1388-1394.
52. Menezes NM, Gray ML, Hartke JR, Burstein D. T2 and T1rho MRI in articular cartilage systems. Magn Reson Med 2004; 51:503-509.
53. Burstein D, Gray ML, Hartman AL, Gipe R, Foy BD. Diffusion of small solutes in cartilage as measured by nuclear magnetic resonance (NMR) spectroscopy and imaging. J Orthop Res 1993; 11:465-478.
54. Hsu EW, Setton LA. Diffusion tensor microscopy of the intervertebral disc annulus fibrosus. Magn Reson Med 1999; 41:992-999.
55. Potter K, Butler JJ, Horton WE, Spencer RG. Response of engineered cartilage tissue to biochemical agents as studied by proton magnetic resonance microscopy. Arthritis Rheum 2000; 43(7):1580-1590.
56. Toffanin R, Mlynarik V, Russo S, Szomolanyi P, Piras A, Vittur F. Proteoglycan depletion and magnetic resonance parameters of articular cartilage. Arch Biochem Biophys 2001; 390:235-242.
57. Berg A, Singer T, Moser E. High-resolution diffusivity imaging at 3.0 T for the detection of degenerative changes: a trypsin-based arthritis model. Invest Radiol 2003; 38:460-466.
58. Mlynarik V, Sulzbacher I, Bittsansky M, Fuiko R, Trattnig S. Investigation of apparent diffusion constant as an indicator of early degenerative disease in articular cartilage. J Magn Reson Imaging 2003; 17:440-444.
59. Nieminen MT, Toyras J, Rieppo J, Hakumaki JM, Silvennoinen J, Helminen HJ, Jurvelin JS. Quantitative MR microscopy of enzymatically degraded articular cartilage. Magn Reson Med 2000; 43:676-681.
60. Nieminen MT, Menezes NM, Williams A, Burstein D. T2 of articular cartilage in the presence of Gd-DTPA2. Magn Reson Med 2004; 51:1147-1152.
61. Nieminen MT, Toyras J, Laasanen MS, Silvennoinen J, Helminen HJ, Jurvelin JS. Prediction of biomechanical properties of articular cartilage with quantitative magnetic resonance imaging. J Biomech 2004; 37:321-328.
62. Nissi MJ, Toyras J, Laasanen, MS Rieppo J, Saarakkala S, Lappalainen R, Jurvelin JS, Nieminen MT. Proteoglycan and collagen sensitive MRI evaluation of normal and degenerated articular cartilage. J Orthop Res 2004; 22:557-564.
63. Samosky JT, Burstein D, Grimson WE, Howe R, Martin S, Gray ML. Correlation of GAG distribution measured by dGEMRIC and spatially-localized mechanical stiffness in the human tibial plateau. J Orthop Res 2004; (in press).
64. Burstein D, Bashir A, Gray ML. MRI techniques in early stages of cartilage disease. Invest Radiol 2000; 35:622-638.
65. Gray ML, Burstein D, Xia Y. Biochemical (and functional) imaging of articular cartilage. Semin Musculoskelet Radiol 2001; 5:329-343.
66. Loeuille D, Olivier P, Watrin A, Grossin L, Gonord P, Fuillot G, Etienne S, Blum A, Netter P, Gillet P. The biochemical content of articular cartilage: an original MRI approach. Biorheology 2002; 39:269-276.
67. Burstein D, Gray M. New MRI techniques for imaging cartilage. J Bone Joint Surg Am 2003; 85-A(Suppl. 2):70-77.
68. Gold GE, McCauley TR, Fray ML, Disler DG. What's new in cartilage? Radiographics 2003; 23:1227-1242.
69. Gray ML, Eckstein F, Peterfy C, Dahlberg L, Kim Y, Sorensen A. Toward imaging biomarkers for osteoarthritis. Clin Orthop Rel Res 2004; (in press).