Clinical significance of urinary N1,N12-diacetylspermine levels in patients with hepatocellular carcinoma

International Journal of Biological Markers

Volumn 19, Issue 4, 2004, Pages 322-327

  Enjoji, Munechika ^a   Nakamuta, M ^a   Arimura, E ^a   Morizono, S ^a   Kuniyoshi, M ^a   Fukushima, M ^a   Kotoh, K ^a   Nawata, H ^a  

^a KYUSHU UNIVERSITY   (Japan)

Author keywords

Diacetylspermine; Hepatocellular carcinoma; Polyamine; Tumor marker

Indexed keywords

ALPHA FETOPROTEIN; CREATININE; DECARBOXYPROTHROMBIN; N1,N12 DIETHYLSPERMINE; TUMOR MARKER;

ADVANCED CANCER; ARTICLE; BENIGN TUMOR; CALCULATION; CANCER GROWTH; CANCER STAGING; CANCER SURVIVAL; CATHETER ABLATION; CHEMOEMBOLIZATION; CONTROLLED STUDY; DIAGNOSTIC VALUE; DISEASE ACTIVITY; DISEASE SEVERITY; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; INTERMETHOD COMPARISON; LIVER CELL CARCINOMA; LIVER CIRRHOSIS; LIVER DISEASE; LIVER RESECTION; MAJOR CLINICAL STUDY; REFERENCE VALUE; SAMPLE SIZE; SENSITIVITY AND SPECIFICITY; TREATMENT OUTCOME; URINALYSIS; URINE LEVEL;

EID: 12344255894     PISSN: 03936155     EISSN: None     Source Type: Journal    
DOI: 10.5301/JBM.2008.4964     Document Type: Article

References (22)

1. Russell DH. Putrescine and spermidine biosynthesis in the development of normal and anucleolate mutants of Xenopus laevis. Proc Natl Acad Sci USA 1971; 68: 523-8.
2. Russell DH, Levy CC. Polyamine accumulation and biosynthesis in a mouse L1210 leukemia. Cancer Res 1971; 31: 248-51.
3. Russell DH. Increased polyamine concentrations in the urine of human cancer patients. Nature New Biol 1971; 233: 144-5.
4. Russell DH, Levy CC, Schimpff SC, Hawk IA. Urinary polyamines in cancer patients. Cancer Res 1971; 31: 1555-8.
5. Löser C, Fölsch UR, Paprotny C, Creutzfeldt W. Polyamines in colorectal cancer, evaluation of polyamine concentrations in colon tissue, serum and urine of 50 patients with colorectal cancer. Cancer 1990; 65: 958-66.
6. Bachrach U. Polyamines as markers of malignancy. Prog Drug Res 1992; 39: 9-33.
7. Hiramatsu K, Kamei S, Sugimoto M, Kinoshita K, Iwasaki K, Kawakita M. An improved method of determining free and acetylated polyamines by HPLC involving an enzyme reactor and an electrochemical detector. J Biochem 1994; 115: 584-9.
8. 12-diacetylspermine as components commonly occurring in normal human urine. J Biochem 1995; 117: 107-12.
9. 12-diacetylspermine as indicators of neoplastic diseases. J Cancer Res Clin Oncol 1995; 121: 317-9.
10. 12-diacetylspermine in urine as novel markers of malignancy. J Cancer Res Clin Oncol 1997; 123: 539-45.
11. 8-diacetylspermidine and development of an enzyme-linked immunosorbent assay (ELISA) system for its sensitive and specific detection. J Biochem 1997; 121: 1134-8.
12. 12-diacetylspermidine in human urine. J Biochem (Tokyo) 1998; 124: 231-6.
13. 12-diacetylspermine using monoclonal antibodies. J Cancer Res Clin Oncol 1997; 123: 539-45.
14. Liver Cancer Study Group of Japan. Classification of primary liver cancer, 1st English ed. Tokyo: Kanehara Press, 1997; 28-40.
15. Heby O, Marton LJ, Wilson CB, Martinez HM. Polyamine metabolism in a rat brain tumor cell line: its relationship to the growth rate. J Cell Physiol 1982; 86: 511-22.
16. McCann PP, Tardif C, Mamont PS, Schuber F. Biphasic induction of ornithine decarboxylase and putrescine levels in growing HTC cells. Biochem Biophys Res Commun 1975; 64: 336-41.
17. Sunkara PS, Ramakrishna S, Nishioka K, Rao PN. The relationship between levels and rates of synthesis of polyamines during mammalian cell cycle. Life Sci 1981; 28: 1497-506.
18. Tomori A, Nishiguchi S, Kuroki T, et al. Point mutation of ornithine decarboxylase gene in human hepatocellular carcinoma. Cancer Res 1995; 55: 3500-3.
19. 1-acetyltransferase? the turning point in polyamine metabolism. FASEB J 1993; 7: 653-61.
20. 1-acetyltransferase on polyamine pool dynamics, cell growth, and sensitivity to polyamine analogs. J Biol Chem 2000; 275: 38319-28.
21. Heby O. Role of polyamines in the control of cell proliferation and differentiation. Differentiation 1981; 14: 1-20.
22. Pösö H, Pegg AE. Effect of α-difluoromethylornithine on polyamine and DNA synthesis in regenerating rat liver: reversal of inhibition of DNA synthesis by putrescine. Biochim Biophys Acta 1982; 696: 179-86.