Pretreatment with oral anticoagulants decreases platelet activation in patients before and after percutaneous coronary intervention

Thrombosis and Haemostasis

Volumn 88, Issue 6, 2002, Pages 924-930

  Ten Berg, Jurriën M ^a   Gerritsen, Wim B M ^a   Haas, Fred J L M ^a   Kelder, Johannes C ^a   Verheugt, Freek W A ^b   Thijs Plokker, H W ^a  

^a ST ANTONIUS HOSPITAL   (Netherlands)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Flow cytometry; Oral anticoagulants; Percutaneous coronary intervention; PFA 100 analyzer; Platelets

Indexed keywords

ACETYLSALICYLIC ACID; ANTICOAGULANT AGENT; ANTILIPEMIC AGENT; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM ANTAGONIST; CLOPIDOGREL; COUMARIN DERIVATIVE; GLYCERYL TRINITRATE; HEPARIN; IOPROMIDE; PADGEM PROTEIN;

ADULT; AGED; ANALYZER; ANGIOCARDIOGRAPHY; ARTICLE; BLEEDING; BLOOD CLOTTING PARAMETERS; CLINICAL OBSERVATION; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORONARY ARTERY DILATATION; CORONARY ARTERY THROMBOSIS; DRUG EFFECT; FEMALE; FLOW CYTOMETRY; HUMAN; INGUINAL REGION; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROTHROMBIN TIME; RANDOMIZED CONTROLLED TRIAL; STABLE ANGINA PECTORIS; THROMBOCYTE; THROMBOCYTE ACTIVATION; THROMBOCYTE COUNT; THROMBOCYTE FUNCTION; TRANSLUMINAL CORONARY ANGIOPLASTY;

EID: 12244288317     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0037-1613335     Document Type: Article

References (28)

1. Mruk JS, Chesebro JH, Webster MWI. Platelet aggregation and interaction with the coagulation system: Implications for antithrombotic therapy in arterial thrombosis. Coronary Artery Dis 1990; 1: 149-55.
2. Mizuno O, Hojo Y, Ikeda U, Katsuki T, Fakazawa H, Kirosaki K, Fujikawa H, Shimada K. Assessment of coagulation and platelet activation on coronary sinus blood induced by transcatheter coronary intervention for narrowing of the left anterior descending coronary artery. Am J Cardiol. 2000; 85: 154-60.
3. Serruys PW, Herrman JP, Simon R, Rutsch W, Bode C, Umans VAWM, Fox KAA, Close P, Deckers JW, for the Helvetica Investigators. A comparison of hirudin with heparin in the prevention of restenosis after coronary angioplasty. N Engl J Med 1995; 333: 757-63.
4. Bittl JA, Chaitman BR, Feit F. Bivalirudin versus heparin during coronary angioplasty for unstable or post-infarction angina: Final reanalysis of the Bivalirudin Angioplasty Study. Am Heart J 2001 (in press).
5. Ten Berg JM, Kelder JC, Suttorp MJ, Mast EG, Bal E, Ernst SMPG, Verheught FWA, Plokker HWM. Effect of coumarins started before coronary angioplasty on acute complications and long-term follow-up: A randomized trial. Circulation 2000; 102: 386-91.
6. Michelson AD. Flow cytometry: A clinical test of platelet function. Blood 1996; 87: 4925-36.
7. Mammen EF, Comp PC, Gosselin R, Greenberg C, Hoots WK, Kessler CM, Larkin EC, Liles D, Nugen DJ. PFA-100TM system: A new method for assessment of platelet dysfunction. Sem Thromb Hemost 1998; 24: 195-202.
8. Beaumont van W. Evaluation of hemoconcentration from hematocrit measurements. J Appl Physiol 1972; 32: 712-3.
9. Merten M, Thiagarajan P. P-selectin expression on platelets determines size and stability of platelet aggregates. Circulation 2000; 102: 1931-6.
10. Merten M, Chow T, Hellums D, Thiagarajan P. A new role for P-selectin in shear-induced platelet aggregation. Circulation 2000; 102: 2045-50.
11. Colman RW, Hirsh J, Marder VJ, Salzman EW. Hemostasis and Thrombosis. 3rd ed 1994.
12. Kolarov P, Tschoepe D, Nieuwenhuis, HK, Gries FA, Strauer B, Schultheiß HP. PTCA: Periprocedural platelet activation. Part II of the Duesseldorf PTCA Platelet Study (DPPS). Eur Heart J 1996; 17: 1216-22.
13. Tschoepe D, Schultheiß HP, Kolarov P, Schwippert B, Dannehl K, Volksw D, Nieuwenhuis HK, Kehrel B, Strauer B, Gries FA. Platelet membrane activation markers are predictive for increased risk of acute ischemic events after PTCA. Circulation 1993; 88: 37-42.
14. Kabbani SS, Watkins MW, Ashikaga T, Terrien EF, Holoch PA, Sobel BE, Schneider DJ. Platelet reactivity characterized prospectively. A determinant of outcome 90 days after percutaneous coronary intervention. Circulation 2001; 104: 181-6.
15. Taylor ML, Ilton MK, Misso NLA, Watkins DN, Hung J, Thompson PJ. The effect of aspirin on thrombin stimulated platelet adhesion receptor expression and the role of neutrophils. Br J Clin Pharmacol 1998; 46: 139-45.
16. Ortel TL, James AH, Thames EH, Moore KD, Greenberg CS. Assessment of primary hemostasis by PFA-100® analysis in a tertiary care center. Thromb Haemost 2000; 84: 93-7.
17. Gawaz M, Neumann FJ, Ott I, Rudiger S, Schömig A. Changes in membrane glycoproteins in circulating platelets after coronary stent implantation. Heart 1996; 76: 166-72.
18. Knight CJ, Panesar M, Wilson DJ, Patrineli A, Chronos N, Wright C, Clarke D, Patel D, Fox K, Goodall AH. Increased platelet responsiveness following coronary stenting. Heparin as a possible aetiological factor in stent thrombosis. Eur Heart J 1998; 19: 1239-48.
19. Michelson AD, Bernard MR, Hechtman HB, MacGregor H, Connolly R, Loscalzo J, Valeri CR. In vivo tracking of platelets: Circulating degranulated platelets rapidly lose surface P-selectin but continue to circulate and function. Proc Natl Acad Sci USA 1996; 93: 11877-82.
20. Gawaz, Neumann F-J, Ott I, May A, Schömig A. Platelet activation and coronary stent implantation. Effect of antithrombotic therapy. Circulation 1996; 94: 279-85.
21. Merlini PA, Ardissino D, Bauer KA, Oltrona L, Pezzano A, Bottasso B, Rosenberg RD, Mannucci PM. Persistent thrombin generation during heparin therapy in patients with acute coronary syndromes. Circulation 1997; 17: 1325-30.
22. Thompson C, Forbes CD, Prentice CRM. The potentiation of platelet aggregation and adhesion by heparin in vitro and in vivo. Clin Sci Mol Med 1973; 45: 485-94.
23. Xiao Z, Theroux P. Platelet activation with unfractionated heparin at therapeutic concentrations and comparisons with a low-molecular-weight heparin and with a direct thrombin inhibitor. Circulation 1999; 97: 251-6.
24. Mascelli MA, Kleiman NS, Marciniak SJ, Damaraju L, Weisman HF, Jordan RE. Therapeutic heparin concentrations augment platelet reactivity: Implications for the pharmacologic assessment of the glycoprotein IIb/IIIa antagonist abciximab. Am Heart J 2000; 139: 696-703.
25. Fluck DS, Chenu P, Mills P, Davies A, Street J, Paul E, Balcon R, Layton CA, for the Widest Trial Investigators' Group. Is provisional stenting the effective option? The WIDEST study (Wiktor in the novo stenosis). Heart 2000; 84: 522-28.
26. Di Mario C, Moses JW, Anderson TJ, Bonan R, Muramatsu T, Jain AC, Suarez De Lezo J, Cho SY, Kern M, Meredith IT, Cohen D, Moussa I, Colombo A, on behalf of the DESTINI Study Group. Randomized comparison of elective stent implantation and coronary balloon angioplasty guided by online quantitative angiography and intracoronary Doppler. Circulation 2000; 102: 2938-44.
27. Serruys PW, Unger F, Sousa JE, Jatene A, Bonnier HJRM, Schönberger J, Buller N, Bonser R, Van Den Brand MJB, Van Herwerden LA, Morel M-AM, Van Hout BA, for the Arterial revascularization therapies study group. N Engl J Med 2001; 344: 1117-24.
28. Müller I, Seyfarth M, Rudiger S, Wolf B, Pogatsa-Murray G, Schömig A, Gawaz M. Effect of a high loading dose of clopidogrel on platelet function in patients undergoing coronary stent placement. Heart 2001; 85: 92-3.