Role of the flocculus in mediating vestibular nucleus neuron plasticity during vestibular compensation in the rat

Journal of Physiology

Volumn 545, Issue 3, 2002, Pages 903-911

  Johnston, Alex R ^a   Seckl, Jonathan R ^b   Dutia, Mayank B ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b WESTERN GENERAL HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

1 (5 ISOQUINOLINESULFONYL) 2 METHYLPIPERAZINE; 1 AMINO 1,5 INDANDICARBOXYLIC ACID; 11BETA HYDROXYSTEROID DEHYDROGENASE; 4 AMINOBUTYRIC ACID RECEPTOR; BISINDOLYLMALEIMIDE; GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR; GLUCOCORTICOID RECEPTOR ANTAGONIST; METABOTROPIC RECEPTOR ANTAGONIST; MIFEPRISTONE; PROTEIN KINASE INHIBITOR; PROTEIN SERINE THREONINE KINASE; PROTEIN KINASE C INHIBITOR;

ADAPTATION; ANIMAL CELL; ANIMAL TISSUE; BRAIN SURGERY; CEREBELLUM FLOCCULUS; CONTROLLED STUDY; DEAFFERENTATION; EVOKED BRAIN STEM RESPONSE; LABYRINTHECTOMY; MICROINJECTION; NERVE CELL PLASTICITY; NERVE CELL STIMULATION; NERVE EXCITABILITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; RECEPTOR DOWN REGULATION; REVIEW; VESTIBULAR FUNCTION; VESTIBULAR NUCLEUS; ARTICLE; BRAIN NERVE CELL; CEREBELLUM CORTEX; DOWN REGULATION; MEDIAL VESTIBULAR NUCLEUS; NERVE CELL DIFFERENTIATION; NERVE CELL EXCITABILITY; VESTIBULAR NUCLEUS NERVE CELL;

1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE; ADAPTATION, PHYSIOLOGICAL; ANIMALS; CEREBELLUM; DENERVATION; DRUG ADMINISTRATION SCHEDULE; ENZYME INHIBITORS; INDANS; INDOLES; MALEIMIDES; NEURONAL PLASTICITY; NEURONS; NEURONS, AFFERENT; PROTEIN KINASE C; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, METABOTROPIC GLUTAMATE; VESTIBULAR NUCLEI;

EID: 12244281788     PISSN: 00223751     EISSN: None     Source Type: Journal    
DOI: 10.1113/jphysiol.2002.024281     Document Type: Review

References (45)

1. AIZENMAN, C. D. & LINDEN, D. J. (1999). Regulation of the rebound depolarization and spontaneous firing patterns of deep nuclear neurons in slices of rat cerebellum. Journal of Neurophysiology 82, 1697-1709.
2. AIZENMAN, C. D. & LINDEN, D. J. (2000). Rapid, synaptically driven increases in the intrinsic excitability of cerebellar deep nuclear neurons. Nature Neuroscience 3, 109-111.
3. AZZENA, G. B., MAMELI, O. & TOLU, E. (1979). Cerebellar contribution in compensating the vestibular function. Progress in Brain Research 50, 599-606.
4. BABALIAN, A. L. & VIDAL, P. P. (2000). Floccular modulation of vestibuloocular pathways and cerebellum-related plasticity: An in vitro whole brain study. Journal of Neurophysiology 84, 2514-2528.
5. BALABAN, C. D., FREILINO, M. & ROMERO, G. G. (1999). Protein kinase C inhibition blocks the early appearance of vestibular compensation. Brain Research 845, 97-101.
6. BARMACK, N. H., QIAN, Z. Y., KIM, H. J. & YOSHIMURA, J. (2001). Activity-dependent distribution of protein kinase C-delta within rat cerebellar Purkinje cells following unilateral labyrinthectomy. Experimental Brain Research 141, 6-20.
7. CAMERON, S. A. & DUTIA, M. B. (1997). Cellular basis of vestibular compensation: changes in intrinsic excitability of MVN neurons. NeuroReport 8, 2595-2599.
8. CAMERON, S. A. & DUTIA, M. B. (1999). Lesion-induced plasticity in rat vestibular nucleus neurons dependent on glucocorticoid receptor activation. Journal of Physiology 518, 151-158.
9. COURJON, J. H., FLANDRIN, J. M., JEANNEROD, M. & SCHMID, R (1982). The role of the flocculus in vestibular compensation after hemilabyrinthectomy. Brain Research 239, 251-257.
10. CURTHOYS, I. S. & HALMAGYI, G. M. (1995). Vestibular compensation: a review of the oculomotor, neural, and clinical consequences of unilateral vestibular loss. Journal of Vestibular Research 5, 67-107.
11. CZUBAYKO, U., SULTAN, F., THIER, P. & SCHWARZ, C. (2001). Two types of neurons in the rat cerebellar nuclei as distinguished by membrane potentials and intracellular fillings. Journal of Neurophysiology 85, 2017-2029.
12. DARLINGTON, C. L. & SMITH, P. F. (2000). Molecular mechanisms of recovery from vestibular damage in mammals: recent advances. Progress in Neurobiology 62, 313-325.
13. DE ZEEUW, C. I., HANSEL, C., BIAN, F., KOEKKOEK, S. K., VAN ALPHEN, A. M., LINDEN, D. J. & OBERDICK, J. (1998). Expression of a protein kinase C inhibitor in Purkinje cells blocks cerebellar LTD and adaptation of the vestibulo-ocular reflex. Neuron 20, 495-508.
14. DU LAC, S., RAYMOND, J. L., SEJNOWSKI, T. J. & LISBERGER, S. G. (1995). Learning and memory in the vestibulo-ocular reflex. Annual Review of Neuroscience 18, 409-441.
15. DUTIA, M. B., JOHNSTON, A. R. & McQUEEN, D. S. (1992). Tonic activity of rat medial vestibular nucleus neurons in vitro and its inhibition by GABA. Experimental Brain Research 88, 466-472.
16. DWIVEDI, Y. & PANDEY, G. N. (1999). Administration of dexamethasone up-regulates protein kinase C activity and the expression of gamma and epsilon protein kinase C isozymes in the rat brain. Journal of Neurochemistry 72, 380-387.
17. FFRENCH-MULLEN, J. M. (1995). Cortisol inhibition of calcium currents in guinea pig hippocampal CA1 neurons via G-protein-coupled activation of protein kinase C. Journal of Neuroscience 15, 903-911.
18. GOTO, M. M., ROMERO, G. G. & BALABAN, C. D. (1997). Transient changes in flocculonodular lobe protein kinase C expression during vestibular compensation. Journal of Neuroscience 17, 4367-4381.
19. GRAHAM, B. P. & DUTIA, M. B. (2001). Cellular basis of vestibular compensation: analysis and modelling of the role of the commissural inhibitory system. Experimental Brain Research 137, 387-396.
20. HIDAKA, H., INAGAKI, M., KAWAMOTO, S. & SASAKI, Y. (1984). Isoquinolinesulfonamides, novel and potent inhibitors of cyclic nucleotide dependent protein kinase and protein kinase C. Biochemistry 23, 5036-5041.
21. HIM, A. & DUTIA, M. B. (2001). Intrinsic excitability changes in vestibular nucleus neurons after unilateral deafferentation. Brain Research 908, 58-66.
22. JEANNEROD, M., COURJON, J. H., FLANDRIN, J. M. & SCHMID, R. (1981). Supravestibular control of vestibular compensation after hemilabyrinthectomy in the cat. In Lesion-Induced Neuronal Plasticity in Sensorimotor Systems, ed. FLOHR, H. & PRECHT, W., pp. 208-220. Springer, Berlin.
23. JOELS, M. (2001). Corticosteroid actions in the hippocampus. Journal of Neuroendocrinology 13, 657-669.
24. B receptors during vestibular compensation. NeuroReport 12, 597-600.
25. JOHNSTON, A. R., MACLEOD, N. K. & DUTIA, M. B. (1994). Ionic conductances contributing to spike repolarization and after-potentials in rat medial vestibular nucleus neurons. Journal of Physiology 481, 61-77.
26. KITAHARA, T., TAKEDA, N., SAIKA, T., KUBO, T. & KIYAMA, H. (1997). Role of the flocculus in the development of vestibular compensation: immunohistochemical studies with retrograde tracing and flocculectomy using Fos expression as a marker in the rat brainstem. Neuroscience 76, 571-580.
27. LLINAS, R., WALTON, K., HILLMAN, D. E. & SOTELO, C. (1975). Inferior olive: its role in motor learing. Science 190, 1230-1231.
28. MOISAN, M. P., SECKL, J. R., BRETT, L. P., MONDER, C., AGARWAL, A. K., WHITE, P. C. & EDWARDS, C. R. W. (1990a). 11β-hydroxysteroid dehydrogenase mRNA expression, bioactivity and immunoreactivity in rat cerebellum. Journal of Neuroendocrinology 2, 853-858.
29. MOISAN, M. P., SECKL, J. R. & EDWARDS, C. R. W. (1990b). 11 betahydroxysteroid dehydrogenase bioactivity and messenger RNA expression in rat forebrain: localization in hypothalamus, hippocampus, and cortex. Endocrinology 127, 1450-1455.
30. MORONI, F., LOMBARDI, G., THOMSEN, C., LEONARDI, P., ATTUCCI, S., PERUGINELLI, F., TORREGROSSA, S. A., PELLEGRINI-GIAMPIETRO, D. E., LUNEIA, R. & PELLICCIARI, R. (1997). Pharmacological characterization of 1-aminoindan-1,5-dicarboxylic acid, a potent mGluR1 antagonist. Journal of Pharmacology and Experimental Therapeutics 281, 721-729.
31. PAVLIDES, C., KIMURA, A., MAGARINOS, A. M. & MCEWEN, B. S. (1995). Hippocampal homosynaptic long-term depression/depotentiation induced by adrenal steroids. Neuroscience 68, 379-385.
32. RIS, L., CAPRON, B., VIBERT, N., VIDAL, P. P. & GODAUX, E. (2001). Modification of the pacemaker activity of vestibular neurons in brainstem slices during vestibular compensation in the guinea pig. European Journal of Neuroscience 13, 2234-2240.
33. RIS, L. & GODAUX, E. (1998). Neuronal activity in the vestibular nuclei after contralateral or bilateral labyrinthectomy in the alert guinea pig. Journal of Neurophysiology 80, 2352-2367.
34. SEEMUNGAL, B. M., GRESTY, M. A. & BRONSTEIN, A. M. (2001). The endocrine system, vertigo and balance. Current Opinion in Neurology 14, 27-34.
35. SHORS, T. J. (2001). Acute stress rapidly and persistently enhances memory formation in the male rat. Neurobiology of Learning and Memory 75, 10-29.
36. SMITH, P. F. & CURTHOYS I. S. (1989). Mechanisms of recovery following unilateral labyrinthectomy: a review. Brain Research Reviews 14, 155-180.
37. SOUSA, R. J., TANNERY, N. H. & LAFER, E. M. (1989). In situ hybridization mapping of glucocorticoid receptor messenger ribonucleic acid in rat brain. Molecular Endocrinology 3, 481-494.
38. TOULLEC, D., PIANETTI, P., COSTE, H., BELLEVERGUE, P., GRAND-PERRET, T., AJAKANE, M., BAUDET, V., BOISSIN, P., BOURSIER, E., LORIOLLE, F., DUHAMEL, L., CHARON, D. & KIRILOVSKY, J. (1991). The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C. Journal of Biological Chemistry 266, 15771-15781.
39. VIBERT, N., BERANECK, M., BANTIKYAN, A. & VIDAL, P. P. (2000). Vestibular compensation modifies the sensitivity of vestibular neurons to inhibitory amino acids. NeuroReport 11, 1921-1927.
40. XIA, J., CHUNG, H. J., WIHLER, C., HUGANIR, R. L. & LINDEN, D. J. (2000). Cerebellar long-term depression requires PKC-regulated interactions between GluR2/3 and PDZ domain-containing proteins. Neuron 28, 499-510.
41. XU, L., HOLSCHER, C., ANWYL, R. & ROWAN, M. J. (1998). Glucocorticoid receptor and protein/RNA synthesis-dependent mechanisms underlie the control of synaptic plasticity by stress. Proceedings of the National Academy of Sciences of the USA 95, 3204-3208.
42. YAMAMOTO, T., YAMANAKA, T. & MATSUNAGA, T. (2000). The effect of stress application on vestibular compensation. Acta Otolaryngologica 120, 504-507.
43. YAMANAKA, T., HIM, A., CAMERON, S. A. & DUTIA, M. B. (2000). Rapid compensatory changes in GABA receptor efficacy in rat vestibular neurons after unilateral labyrinthectomy. Journal of Physiology 523, 413-424.
44. YAMANAKA, T., SASA, M., AMANO, T., MIYAHARA, H. & MATSUNAGA, T. (1995). Role of glucocorticoid in vestibular compensation in relation to activation of vestibular nucleus neurons. Acta Otolaryngologica Suppl. 519, 168-172.
45. YAU, J. L., NOBLE, J., KENYON, C.J., HIBBERD, C., KOTELEVTSEV, Y., MULLINS, J. J. & SECKL, J. R. (2001). Lack of tissue glucocorticoid reactivation in 11beta -hydroxysteroid dehydrogenase type 1 knockout mice ameliorates age-related learning impairments. Proceedings of the National Academy of Sciences of the USA 98, 4716-4721.