Apolipoprotein e in idiopathic nephrotic syndrome and focal segmental glomerulosclerosis

Kidney International

Volumn 63, Issue 2, 2003, Pages 686-695

  Bruschi, Maurizio ^a,b,c,d,e   Catarsi, Paolo ^a,b,c,d,e   Candiano, Giovanni ^a,b,c,d,e   Rastaldi, Maria Pia ^a,b,c,d,e   Musante, Luca ^a,b,c,d,e   Scolari, Francesco ^a,b,c,d,e   Artero, Mary ^a,b,c,d,e   Carraro, Michele ^a,b,c,d,e   Carrea, Alba ^a,b,c,d,e   Caridi, Gianluca ^a,b,c,d,e   Zennaro, Cristina ^a,b,c,d,e   Sanna Cherchi, Simone ^a,b,c,d,e   Viola, Fabio Battista ^a,b,c,d,e   Ferrario, Franco ^a,b,c,d,e   Perfumo, Francesco ^a,b,c,d,e   Ghiggeri, Gian Marco ^a,b,c,d,e  

^a G GASLINI INSTITUTE   (Italy)

^b SAN CARLO BORROMEO HOSPITAL   (Italy)

^c SPEDALI CIVILI   (Italy)

^d UNIVERSITY OF TRIESTE   (Italy)

^e UNIVERSITY OF PARMA   (Italy)

Author keywords

ApoE genotype; Cell matrix; Cholesterol absorption; Hyperlipidemia; Lipid metabolism; Mesangial cell proliferation; Progressive renal disease

Indexed keywords

APOLIPOPROTEIN E;

ALLELE; ARTICLE; BLOOD LEVEL; CONTROLLED STUDY; CORRELATION ANALYSIS; DOWN REGULATION; FEMALE; GENETIC VARIABILITY; GENOTYPE; GLOMERULOSCLEROSIS; HAPLOTYPE; HISTOLOGY; HOMOZYGOSITY; HUMAN; HUMAN TISSUE; HYPERCHOLESTEROLEMIA; IMMUNOFLUORESCENCE; LIPID METABOLISM; MAJOR CLINICAL STUDY; MALE; MEMBRANOUS GLOMERULONEPHRITIS; NEPHROTIC SYNDROME; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEINURIA; URINE LEVEL;

EID: 12244279083     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1755.2003.00777.x     Document Type: Article

References (30)

1. JOVEN J, VILLABONA C, VILELLA E, et al: Abnormalities of lipoprotein metabolism in patients with the nephrotic syndrome. N Engl J Med 323:579-584, 1990
2. WHEELER DC, BERNARD DB: Lipid abnormalities in the nephrotic syndrome: Causes, consequences, and treatment. Am J Kidney Dis 23:331-346, 1994
3. SHORT CD, DURRINGTON PN, MALLICK NP, et al: Serum and urinary high density lipoproteins in glomerular disease with proteinuria. Kidney Int 29:1224-1228, 1986
4. MUNTNER P, CORESH J, SMITH JC, et al: Plasma lipids and risk of developing renal dysfunction: The atherosclerosis risk in communities study. Kidney Int 58:293-301, 2000
5. AALTO-SETALA K, BENLIAN P, BOWYER D, et al: European Lipoprotein Club: Report of the 20th annual conference, Tutzing, 8-11 September 1997. Atherosclerosis 137:223-229, 1998
6. WEISGRABER KH: Apolipoprotein E distribution among human plasma lipoproteins: Role of the cysteine-arginine interchange at residue 112. J Lipid Res 31:1503-1511, 1990
7. CHEN G, PAKA L, KAKO Y, et al: A protective role for kidney apolipoprotein E. Regulation of mesangial cell proliferation and matrix expansion. J Biol Chem 276:49142-49147, 2001
8. ZHANG SH, REDDICK RL, PIEDRAHITA JA, MAEDA N: Spontaneous hypercholesterolemia and arterial lesions in mice lacking apolipoprotein E. Science 258:468-471, 1992
9. KNOWLES JW, REDDICK RL, JENNETTE JC, et al: Enhanced atherosclerosis and kidney dysfunction in eNOS(-/-)Apoe(-/-) mice are ameliorated by enalapril treatment. J Clin Invest 105:451-458, 2000
10. WEISGRABER KH, RALL SC JR, MAHLEY RW: Human E apoprotein heterogeneity. Cysteine-arginine interchanges in the amino acid sequence of the apo-E isoforms. J Biol Chem 256:9077-9083, 1981
11. ASAMI T, CIOMARTAN T, HAYAKAWA H, et al: Apolipoprotein E epsilon 4 allele and nephrotic glomerular diseases in children. Pediatr Nephrol 13:233-236, 1999
12. ATTILA G, NOYAN A, KARABAY BAYAZIT A, et al: Apolipoprotein E polymorphism in childhood nephrotic syndrome. Pediatr Nephrol 17:359-362, 2002
13. ODA H, YORIOKA N, UEDA C, et al: Apolipoprotein E polymorphism and renal disease. Kidney Int 56(Suppl 71):S25-S27, 1999
14. OIKAWA S, MATSUNAGA A, SAITO T, et al: Apolipoprotein E Sendai (arginine 145→proline): A new variant associated with lipoprotein glomerulopathy. J Am Soc Nephrol 8:820-823, 1997
15. MORIYAMA K, SASAKI J, TAKADA Y, et al: Characterization of a novel variant of apolipoprotein E, E2 Fukuoka (Arg-224 → Gln) in a hyperlipidemic patient with xanthomatosis. Biochim Biophys Acta 1301:185-190, 1996
16. ANDO M, SASAKI J, HUA H, et al: A novel 18-amino acid deletion in apolipoprotein E associated with lipoprotein glomerulopathy. Kidney Int 56:1317-1323, 1999
17. MATSUNAGA A, SASAKI J, KOMATSU T, et al: A novel apolipoprotein E mutation, E2 (Arg25Cys), in lipoprotein glomerulopathy. Kidney Int 56:421-427, 1999
18. SAKATSUME M, KADOMURA M, SAKATA I, et al: Novel glomerular lipoprotein deposits associated with apolipoprotein E2 homozygosity. Kidney Int 59:1911-1918, 2001
19. MARGAGLIONE M, SERIPA D, GRAVINA C, et al: Prevalence of apolipoprotein E alleles in healthy subjects and survivors of ischemic stroke: An Italian Case-Control Study. Stroke 29:399-403, 1998
20. DONOHOE GG, SALOMAKI A, LEHTIMAKI T, et al: Rapid identification of apolipoprotein E genotypes by multiplex amplification refractory mutation system PCR and capillary gel electrophoresis. Clin Chem 45:143-146, 1999
21. CANDIANO G, MUSANTE L, CARRARO M, et al: Apolipoproteins prevent glomerular albumin permeability induced in vitro by serum from patients with focal segmental glomerulosclerosis. J Am Soc Nephrol 12:143-150, 2001
22. BJELLQVIST B, PASQUALI C, RAVIER F, et al: A nonlinear wide-range immobilized pH gradient for two-dimensional electrophoresis and its definition in a relevant pH scale. Electrophoresis 14:1357-1365, 1993
23. OHSAWA H, YAMABE H, OZAWA K, et al: Intraglomerular lipid deposition in experimental focal glomerular sclerosis in the rat [letter]. Nephron 50:66, 1988
24. WHEELER DC, NAIR DR, PERSAUD JW, et al: Effects of dietary fatty acids in an animal model of focal glomerulosclerosis. Kidney Int 39:930-937, 1991
25. HIRANO T, MOROHOSHI T: Treatment of hyperlipidemia with probucol suppresses the development of focal and segmental glomerulo-sclerosis in chronic aminonucleoside nephrosis. Nephron 60:443-447, 1992
26. KASISKE BL, O'DONNELL MP, GARVIS WJ, KEANE WF: Pharmacologic treatment of hyperlipidemia reduces glomerular injury in rat 5/6 nephrectomy model of chronic renal failure. Circ Res 62:367-374, 1988
27. DIAMOND JR, KARNOVSKY MJ: Exacerbation of chronic amino-nucleoside nephrosis by dietary cholesterol supplementation. Kidney Int 32:671-677, 1987
28. MUSO E, MUNE M, FUJII Y, et al: Low density lipoprotein apheresis therapy for steroid-resistant nephrotic syndrome. Kansai-FGS-Apheresis Treatment (K-FLAT) Study Group. Kidney Int 56 (Suppl 71):S122-125, 1999
29. BLUE ML, WILLIAMS DL, ZUCKER S, et al: Apolipoprotein E synthesis in human kidney, adrenal gland, and liver. Proc Natl Acad Sci USA 80:283-287, 1983
30. WALLIS SC, ROGNE S, GILL L, et al: The isolation of cDNA clones for human apolipoprotein E and the detection of apoE RNA in hepatic and extrahepatic tissues. EMBO J 2:2369-2373, 1983