IRS-4 mediated mitogenic signalling by insulin and growth hormone in LB cells, a murine T-cell lymphoma devoid of IGF-I receptors

Cellular Signalling

Volumn 15, Issue 4, 2003, Pages 385-394

  Ursø, Birgitte ^a,e   Ilondo, M Mapoko ^a,e   Holst, Patricia A ^a   Christoffersen, Claus T ^a,f   Ouwens, Margriet ^b   Giorgetti, Sophie ^c   Van Obberghen, E ^c   Naor, David ^d   Tornqvist, Hans ^a   De Meyts, Pierre ^a  

^a HAGEDORN RESEARCH INSTITUTE   (Denmark)

^b LEIDEN UNIVERSITY   (Netherlands)

^c INSERM   (France)

^d Tissue Typing Unit and Lautenberg Center for General and Tumor Immunology   (Israel)

^e NOVO NORDISK A S   (Denmark)

^f H LUNDBECK A S   (Denmark)

Author keywords

Bell shaped; ERK; Growth hormone; Insulin; IRS 4; Mitogenesis; PI3 kinase; Ras; STAT5

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; GROWTH HORMONE; GROWTH HORMONE RECEPTOR; INSULIN; INSULIN RECEPTOR; INSULIN RECEPTOR SUBSTRATE 4; MITOGEN ACTIVATED PROTEIN KINASE; PD 980594; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOTRANSFERASE INHIBITOR; PROTEIN P70; RAPAMYCIN; RAS PROTEIN; SOMATOMEDIN C RECEPTOR; STAT5 PROTEIN; THYMIDINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DNA SYNTHESIS; DOSE RESPONSE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME ASSAY; HORMONE BINDING; MITOGENESIS; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; T CELL LYMPHOMA;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; CATTLE; ENZYME ACTIVATION; FEMALE; GROWTH HORMONE; HUMANS; INSULIN; LYMPHOMA, T-CELL; MICE; MICE, INBRED BALB C; MITOGENS; PHOSPHOPROTEINS; PHOSPHORYLATION; RECEPTOR, IGF TYPE 1; SIGNAL TRANSDUCTION; TUMOR CELLS, CULTURED; TYROSINE;

MURINAE;

EID: 12244268682     PISSN: 08986568     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0898-6568(02)00113-4     Document Type: Article

References (55)

1. Hofmann C., Goldfine I.D., Whittaker J. J. Biol. Chem. 264:1989;8606-8611.
2. Baserga R., Hongo A., Rubini M., Prisco M., Valentinis B. Biochim. Biophys. Acta. 1332:1997;105-126.
3. Conover A., Hintz R.L., Rosenfeld R.G. Horm. Metab. Res. 21:1989;59-63.
4. Flier J.S., Usher P., Moses A.C. Proc. Natl. Acad. Sci. U. S. A. 83:1986;664-668.
5. Ebina Y., Ellis L., Jarnagin K., Edery M., Graf L., Clauser E.et al. Cell. 40:1985;747-758.
6. Ullrich A., Bell J.R., Chen E.Y., Herrera R., Petruzzelli L.M., Dull T.J.et al. Nature. 313:1985;756-761.
7. Ullrich A., Gray A., Tam A.W., Yang-Feng T., Tsubokawa M., Collins C.et al. EMBO J. 5:1986;2503-2512.
8. De Meyts P. Diabetalogia. 37:1994;135-148.
9. Soos M.A., Whittaker J., Lammers R., Ullrich A., Siddle K. Biochem. J. 270:1990;383-390.
10. White M.F. Mol. Cell. Biochem. 182:1998;3-11.
11. Seger R., Krebs E.G. FASEB J. 9:1995;726-735.
12. King W.G., Mattaliano M.D., Chan T.O., Tsichlis P.N., Brugge J.S. Mol. Cell. Biol. 17:1997;4406-4418.
13. Kilgour E., Gout I., Anderson N.G. Biochem. J. 315:1996;517-522.
14. Ridderstrale M., Tornqvist H. Biochem. Biophys. Res. Commun. 203:1994;306-310.
15. Lavan B.E., Fantin V.R., Chang E.T., Lane W.S., Keller S.R., Leinhard G.E. J. Biol. Chem. 272:1997;21403-21407.
16. Fantin V.R., Keller S.R., Lienhard G.E., Wang L.M. Biochem. Biophys. Res. Commun. 260:1999;718-723.
17. Qu B.-H., Karas M., Koval A., LeRoith D. J. Biol. Chem. 274:2000;31179-31184.
18. Wells J.A. Proc. Natl. Acad. Sci. U. S. A. 93:1996;1-6.
19. Ridderstrale M., Degerman E., Tornqvist H. J. Biol. Chem. 270:1995;3471-3474.
20. Chow J.C., Ling P.R., Qu Z., Laviola L., Ciccarone A., Bistrian B.R.et al. Endocrinology. 137:1996;2880-2886.
21. Teglund S., McKay C., Schuetz E., van Deursen J.M., Stravopodis D., Wang D.et al. Cell. 93:1998;841-850.
22. Yamauchi T., Kaburagi Y., Ueki K., Tsuji Y., Stark G.R., Kerr I.M.et al. J. Biol. Chem. 273:1998;15719-15726.
23. Tornqvist H., Ridderstrale M., Eriksson H., Degerman E. Ann. N.Y. Acad. Sci. 766:1995;469-471.
24. Nickel B.E., Kardami E., Cattini P.A. Endocrinology. 126:1990;971-976.
25. Bulanova E.G., Budagyan A.M., Balura A.V., Agranat V.Z., Yarilin A. Endocrinol. Metab. 4:1997;185-191.
26. Salmon W.D., Daughaday W.H. J. Lab. Clin. Med. 49:1957;825-836.
27. Berneis K., Keller U. Bailliere's Clin. Endocrinol. Metab. 10:1996;337-352.
28. Ruggiero R.A., Bustuoabad O.D., Bonfil R.D., Meiss R.P., Pasqualini C.D. Br. J. Cancer. 51:1985;37-48.
29. Pillemer G., Lugasi-Evgi H., Scharovsky G., Naor D. Int. J. Cancer. 50:1992;80-85.
30. Ish-Shalom D., Christoffersen C.T., Vorwerk P., Sacerdoti-Sierra N., Shymko R.M., Naor D.et al. Diabetologia. 40(Suppl. 2):1997;S25-S31.
31. Fantin V.R., Sparling J.D., Slot J.W., Keller S.R., Leinhard G.E., Lavan B.E. J. Biol. Chem. 273:1998;10726-10732.
32. Lugasi H., Hajos S., Murphy J.R., Strom T.B., Nichols J., Penarroja C.et al. Int. J. Cancer. 45:1990;163-167.
33. Van den Berghe N., Ouwens D.M., Maassen J.A., van Mackelenbergh M.G., Sips H.C., Krans H.M. Mol. Cell. Biol. 14:1994;2372-2377.
34. Ahn J., Rosen O.M., Donner D.B. J. Biol. Chem. 268:1993;16839-16844.
35. Frodin M., Peraldi P., Van Obberghen E. J. Biol. Chem. 269:1994;6207-6214.
36. Whitman M., Downes C.P., Keeler M., Keller T., Cantley L. Nature. 332:1988;644-646.
37. Terada N., Franklin R.A., Lucas J.J., Blenis J., Gelfand E.W. J. Biol. Chem. 268:1993;12062-12068.
38. Hansen J.A., Hansen L.H., Wang X., Kopchick J.J., Gouilleux F., Groner B.et al. J. Mol. Endocrinol. 18:1997;213-221.
39. Ish-Shalom D., Tzivion G., Christoffersen C.T., Urso B., De Meyts P., Naor D. Ann. N.Y. Acad. Sci. 766:1995;409-415.
40. Hansen L.H., Wang X., Kopchick J.J., Bouchelouche P., Nielsen J.H., Galsgaard E.D.et al. J. Biol. Chem. 271:1996;12669-12673.
41. Shahabi N.A., Daaka Y., McAllen K., Sharp B.M. J. Neuroimmunol. 94:1999;48-57.
42. Ueda Y., Hirai Si, Osada Si, Suzuki A., Mizuno K., Ohno S. J. Biol. Chem. 271:1996;23512-23519.
43. Xu S., Khoo S., Dang A., Witt S., Do V., Zhen E.et al. Mol. Endocrinol. 11:1997;1618-1625.
44. Moses A.C., Tsuzaki S., LeRoith D. Insulin-like growth factors: molecular and cellular aspects: is insulin a growth factor? 1999:245-270.
45. Fuh G., Cunningham B.C., Fukunaga R., Nagata S., Goeddel D.V., Wells J.A. J. Sci. 256:1992;1677-1680.
46. Ilondo M.M., Damholt A.B., Cunningham B.A., Wells J.A., De Meyts P., Shymko R.M. Endocrinology. 134:1993;2397-2403.
47. Argetsinger L.S., Campbell G.S., Yang X., Witthuhn B.A., Silvennoinen O., Ihle J.N.et al. Cell. 74:1993;237-244.
48. De Meyts P., Urso B., Christoffersen C.T., Shymko R.M. Ann. N.Y. Acad. Sci. 766:1995;388-401.
49. Schaffer L. Eur. J. Biochem. 221:1994;1127-1132.
50. Fantin V.R., Wang Q., Lienhard G.E., Keller S.R. Am. J. Physiol: Endocrinol. Metab. 278:2000;E127-E133.
51. Fantin V.R., Lavan B.E., Wang Q., Jenkins N.A., Gilbert D.J., Copeland N.G.et al. Endocrinology. 140:1999;1329-1337.
52. Neuman S., Russel D.S. Mol. Brain Res. 72:1999;97-102.
53. Sun H., Tonks N.K., Bar-Sagi D. Science. 266:1994;285-288.
54. Jhun B., Haruta T., Meinkoth J.L., Leitner J.W., Draznin B., Saltiel A.R.et al. Biochemistry. 34:1995;7996-8004.
55. Campbell G.S. J. Pediatr. 131:1997;S42-S44.