Analysis of mutations and bone marrow micronuclei in Big Blue® rats fed leucomalachite green

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 547, Issue 1-2, 2004, Pages 5-18

  Manjanatha, M G ^a   Shelton, S D ^a   Bishop, M ^a   Shaddock, J G ^a   Dobrovolsky, V N ^a   Heflich, R H ^a   Webb, P J ^a   Blankenship, L R ^a   Beland, F A ^a   Greenlees, K J ^b   Culp, S J ^a  

^a NATIONAL CENTER FOR TOXICOLOGICAL RESEARCH   (United States)

^b CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

Author keywords

Big Blue rats; lacI; Leucomalachite green; Mutant frequency; Mutation frequency

Indexed keywords

CARCINOGEN; LEUCOMALACHITE GREEN; MALACHITE GREEN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW; CLONAL VARIATION; CONTROLLED STUDY; DNA ADDUCT; DOSE RESPONSE; EVALUATION; EXPERIMENTAL RAT; FEMALE; GENE MUTATION; GENOTOXICITY; LIVER; LYMPHOCYTE; MICRONUCLEUS; MUTATION RATE; NONHUMAN; PRIORITY JOURNAL; RAT; RISK; STATISTICAL SIGNIFICANCE;

ANILINE COMPOUNDS; ANIMALS; ANIMALS, GENETICALLY MODIFIED; BONE MARROW CELLS; CLONE CELLS; DNA MUTATIONAL ANALYSIS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; LAC OPERON; LIVER; LYMPHOCYTES; MICRONUCLEI, CHROMOSOME-DEFECTIVE; MICRONUCLEUS TESTS; MOLECULAR STRUCTURE; MUTAGENS; MUTATION; RATS; TOXICITY TESTS, CHRONIC;

RODENTIA; SIPROETA STELENES;

EID: 12144288878     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrfmmm.2003.11.009     Document Type: Article

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