Impact of Menopause on Lipid and Bone Metabolism and Effect of Hormone Replacement Therapy

Tokai Journal of Experimental and Clinical Medicine

Volumn 28, Issue 3, 2003, Pages 109-119

  Murano, Takayo ^a   Izumi, Shun Ichiro ^a   Kika, Goh ^a   Haque, Shanta Fahmida ^a   Okuwaki, Shinji ^a   Mori, Akira ^a   Suzuki, Takahiro ^a   Matsubayashi, Hidehiko ^a   Ikeda, Masae ^a   Goya, Kenichi ^a   Makino, Tsunehisa ^a  

^a TOKAI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Aging; Atherogenic index; HRT; Lipids; Menopause; Osteoporosis; Sex hormones

Indexed keywords

ACID PHOSPHATASE TARTRATE RESISTANT ISOENZYME; ALKALINE PHOSPHATASE BONE ISOENZYME; APOLIPOPROTEIN; APOLIPOPROTEIN A1; APOLIPOPROTEIN B; ASPARTIC ACID; CALCITRIOL; CALCIUM ION; CONJUGATED ESTROGEN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MEDROXYPROGESTERONE ACETATE; OSTEOCALCIN; PARATHYROID HORMONE; PHOSPHATE; SEX HORMONE; TRIACYLGLYCEROL;

ADULT; AGING; ARTICLE; ATHEROGENESIS; BONE DENSITY; BONE METABOLISM; BONE MINERAL; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DUAL ENERGY X RAY ABSORPTIOMETRY; FEMALE; HORMONE SUBSTITUTION; HUMAN; HYPERLIPIDEMIA; LIPID METABOLISM; LUMBAR SPINE; MAJOR CLINICAL STUDY; MENOPAUSE; POSTMENOPAUSE OSTEOPOROSIS; QUALITY OF LIFE; TRIACYLGLYCEROL BLOOD LEVEL;

ADULT; ANALYSIS OF VARIANCE; ANIMALS; BONE AND BONES; BONE DENSITY; ESTROGEN REPLACEMENT THERAPY; ESTROGENS; FEMALE; HUMANS; LIPID METABOLISM; MENOPAUSE; MIDDLE AGED; POSTMENOPAUSE;

EID: 12144288827     PISSN: 03850005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (12)

1. Cummings SR, Melton LJ.: Epidemiology and outcomes of osteoporotic fractures. Lancet 359: 1761-7, 2002.
2. Bugliosi R, Caratozzolo V, Caratozzolo A.: Hyperlipidemia, hypertension and atherosclerosis in women. Reality and perspectives. Clin Ter 146: 503-18, 1995.
3. McClung MR.: The menopause and HRT. Prevention and management of osteoporosis. Best Pract Res Clin Endocrinol Metah 17: 53-71, 2003.
4. Dalal D, Rohhins JA.: Management of hyperlipidemia in the elderly population: an evidence-hased approach. South Med J. 2002, 95: 1255-61.
5. Willeit J, Kiechl S.: Biology of arterial atheroma. Cerehrovasc Dis 10 Suppl 5: 1-8, 2000.
6. Despres JP, Lemieux I, Dagenais GR, Cantin B, Lamarche B.: HDL-cholesterol as a marker of coronary heart disease risk: the Quebec cardiovascular study. Atherosclerosis 153: 263-72, 2000.
7. Mukherjee TK, Nathan L, Dinh H, Reddy ST, Chaudhuri G.: 17-epiestriol, an estrogen metabolite, is more potent than estradiol in inhihiting vascular cell adhesion molecule 1 (VCAM-1) mRNA expression. J Biol Chem 278: 11746-52, 2003.
8. Grumhach MM, Auchus RJ.: Estrogen: consequences and implications of human mutations in synthesis and action. J Clin Endocrinol Metah 84: 4677-94, 1999.
9. Sprecher DL.: Targeting triglycerides as prognostic indicators and determining lowest values for patient benefit. Curr Cardiol Rep 3: 424-32, 2001.
10. Williams DB, Moley KH.: Progestin replacement in the menopause: effects on the endometrium and serum lipids. Curr Opin Ohstet Gynecol 6: 284-92, 1994.
11. Sitruk-Ware R.: Progestins in the menopause. J Steroid Biochem Mol Biol 69: 185-93, 1999.
12. Ohmori S, Kanda K, Kawano S, Kambe F, Seo H.: Changes in calcium, PTH and 1,25(OH)2 vitamin D3 during tail-suspension in ovariectomized rats: effects of estrogen administration. Environ Med 44: 75-8, 2000.