Effect of adrenomedullin on c-Met receptor expression after reserpine-induced gastric damage in the rat

European Journal of Pharmacology

Volumn 488, Issue 1-3, 2004, Pages 219-224

  Martinez, Giuseppa ^a   Cantarella, Giuseppina ^a   Cutuli, Vincenza Maria ^a   Loreto, Carla ^a   Prato, Agata ^a   Lempereur, Laurence ^a   Carnazza, Maria Luisa ^a   Amico Roxas, Matilde ^a   Bernardini, Renato ^a   Clementi, Giuseppe ^a  

^a UNIVERSITY OF CATANIA   (Italy)

Author keywords

Adrenomedullin; Gastroprotection; Hepatocyte growth factor; Receptor; Ulcer

Indexed keywords

ADRENOMEDULLIN; MITOGEN ACTIVATED PROTEIN KINASE; RECEPTOR PROTEIN; RESERPINE; SCATTER FACTOR RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; ENZYME PHOSPHORYLATION; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; RAT; STOMACH GLAND; STOMACH INJURY; TISSUE DISTRIBUTION;

ADRENOMEDULLIN; ANIMALS; ANTI-ULCER AGENTS; BLOTTING, WESTERN; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; MALE; MITOGEN-ACTIVATED PROTEIN KINASES; PEPTIDES; PHOSPHORYLATION; PROTEINS; PROTO-ONCOGENE PROTEINS C-MET; RATS; RATS, SPRAGUE-DAWLEY; RESERPINE; SIGNAL TRANSDUCTION; STOMACH ULCER; TUBULIN;

EID: 12144288484     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2004.01.001     Document Type: Article

References (23)

1. Baatar D., Jones M.K., Pai R., Kawanaka H., Szabo I.L., Moon W.S., Tamawski A.S. Selective cycloxygenase-2 blocker delays healing of esophageal, ulcers in rats and inhibits ulceration trigger c-Met hepatocyte growth factor receptor induction and extracellular signal-regulated kinase2 activation. Am. J. Pathol. 160:2002;963-971.
2. Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72:1976;248-254.
3. Clementi G., Caruso A., Cutuli V.M., Mangano N.G., Salomone S., Lempereur L., Prato A., Matera M., Amico-Roxas M. Gastroprotective effect of adrenomedullin administered subcutaneously in the rat. Peptides. 23:2002;1149-1153.
4. Comoglio P.M. Structure, biosynthesis and biochemical properties of the HGF receptor in normal and malignant cell. EXS. 65:1993;131-165.
5. Hori K., Shiota G., Kawasaki H. Expression of hepatocyte growth factor and c-met receptor in gastric mucosa during gastric ulcer healing. Scand. J. Gastroenterol. 35:2000;23-31.
6. Ichiki Y., Kitamura K., Kangawa K., Kawamoto M., Matsuo H., Eto T. Distributio and characterization of immunoreactive adrenomedullin in human tissue and plasma. FEBS Lett. 338:1994;6-10.
7. Kaneko H., Mitsuma T., Nagai H., Mori S., Iyo T., Kusugami K., Tackè Y. Central action of adrenomedullin to prevent ethanol-induced gastric injury through vagal pathways in rats. Am. J. Physiol. 274:1998;R1783-R1788.
8. Kermorgant S., Walker F., Hormi K., Dessirier V., Lewin M.J., Lehy T. Development expression and functionally of hepatocite growth factor and c_Met in human fetal digestive tissues. Gastroenterol. 112:1997;1635-1647.
9. Kitamura K., Kangawa K., Kawamoto M., Ichiki Y., Nakamura S., Matsuo H., Eto T. Adrenomedullin - a novel hypotensive peptide isolated from human pheochromocytoma. Biochem. Biophys. Res. Commun. 192:1993;553-560.
10. Lau H.K., Ogle C.W. The influence of cimetidine, a histamine H2-receptor antagonist, on the gastric effect of reserpine in rats. Eur. J. Pharmacol. 70:1981;139-141.
11. Martinez V., Cuttitta F., Tachè Y. Central action of adrenomedullin to inhibit gastric emptying in rats. Endocrinology. 13:1997;3749-3755.
12. Nishimura S., Takahashi M., Ota S., Hirano M., Hiraishi H. Hepatocyte growth factor accelerates restitution of intestinal epithelial cells. J. Gastroenterol. 33:1998;172-178.
13. Parameswaran N., Nambi P., Brooks D.P., Spielman W.S. Regulation of glomerular mesangial cell proliferation in culture by adrenomedullin. Eur. J. Pharmacol. 372:1999;85-95.
14. Salomone S., Caruso A., Cutuli V.M., Mangano N.G., Prato A., Amico-Roxas M., Bianchi A., Clementi G. Effects of adrenomedullin on the contraction of gastric arteries during reserpine-induced gastric ulcer. Peptides. 24:2003;117-122.
15. Salomone S., Caruso A., Martinez G., Cutuli V.M., Prato A., Bianchi A., Amico-Roxas M., Clementi G. Secretory and vascular effects of adrenomedullin in gastric ulcer: role of CGRP- and adrenomedullin-receptors. Peptides. 24:2003;1175-1180.
16. Sandor V., Cuparencu B. Analysis of the mechanism of the protective activity of some simphatomimetic amines in experimental ulcers. Pharmacology. 15:1977;208-217.
17. Schmassmann A., Stettler C., Poulsom R., Tarasova N., Hirschi C., Flogerzi B., Matsumoto K., Nakamura T., Halter F. Roles of hepatocyte growth factor and its receptor c-met during gastric ulcer healing in rats. Gastroenterology. 113:1997;1858-1872.
18. Tamawski A., Stachura J., Durbin T., Sarfeh I.J., Gergely H. Increased expression of epidermal growth factor receptor during gastric ulcer healing in rats. Gastroenterology. 102:1992;695-698.
19. Tandler C.J., Rios H., Pellegrino de Iraldi A. Differential staining of two subpopulations of Purkinje neurons in rat cerebellum with acid dyes. Biotech. Histochem. 72:1997;231-239.
20. Terano A., Sakata-Horie K., Shimata T., Hiraishi H., Yoshiura K., Yoneda M., Takahashi M., Fujimori T. The role of cellular migration in the repair process of gastric epithelial cells. Life Sci. 69:2001;3083-3089.
21. Wang H., Tomikawa M., Jones K., Pai R., Sarfeh I.J., Tarnawski A.S. Sequential expression of adrenomedullin and its receptor during gastric ulcer healing in rats. Dig. Dis. Sci. 45:2000;591-598.
22. Watanabe S., Hirose M., Wang X.E., Machiro K., Murai T., Kobayashi O., Nagahara A., Sato N. Hepatocyte growth factor accelerates the would repair cultured gastric mucosal cells. Biochem. Biophys. Res. Commun. 199:1994;1453-1460.
23. Wimalawansa S.J. Amylin, calcitonin gene-related peptide, calcitonin, and adrenomedullin: a peptide superfamily. Crit. Rev. Neurobiol. 11:1997;167-239.