Interstitial pneumonia induced by imatinib mesylate: Pathologic study demonstrates alveolar destruction and fibrosis with eosinophilic infiltration [1]

Leukemia

Volumn 18, Issue 3, 2004, Pages 645-646

  Yokayama, T ^a   Miyazawa, K ^a   Kurakawa, E ^a   Nagate, A ^a   Shimamoto, T ^a   Iwaya, K ^a   Akata, S ^a   Aoshima, M ^a   Serizawa, H ^a   Ohyashiki, K ^a  

^a TOKYO MEDICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BCR ABL PROTEIN; HYDROXYUREA; IMATINIB; ANTINEOPLASTIC AGENT; PIPERAZINE DERIVATIVE; PROTEIN TYROSINE KINASE; PYRIMIDINE DERIVATIVE;

ADULT; CASE REPORT; CHRONIC MYELOID LEUKEMIA; COMPUTER ASSISTED TOMOGRAPHY; DIAGNOSTIC PROCEDURE; DRUG RESPONSE; DRUG WITHDRAWAL; DYSPNEA; EDEMA; EOSINOPHIL; FLUORESCENCE IN SITU HYBRIDIZATION; HUMAN; HUMAN CELL; HUMAN TISSUE; INTERSTITIAL PNEUMONIA; LETTER; LUNG ALVEOLUS; LUNG FIBROSIS; LUNG INFILTRATE; MALE; PATHOLOGY; PRIORITY JOURNAL; RASH; SYMPTOMATOLOGY; THORAX RADIOGRAPHY; TRANSBRONCHIAL BIOPSY; CHEMICALLY INDUCED DISORDER; DRUG ANTAGONISM; INTERSTITIAL LUNG DISEASE; LOEFFLER PNEUMONIA; MIDDLE AGED;

ANTINEOPLASTIC AGENTS; HUMANS; LUNG DISEASES, INTERSTITIAL; MALE; MIDDLE AGED; PIPERAZINES; PROTEIN-TYROSINE KINASES; PULMONARY ALVEOLI; PULMONARY EOSINOPHILIA; PULMONARY FIBROSIS; PYRIMIDINES;

EID: 12144288328     PISSN: 08876924     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.leu.2403251     Document Type: Letter

References (5)

1. O'Brien SG, Guilhot F, Larson RA, Gathmann I, Baccarani M, Cervantes F et al. IRIS investigators: Imatinib compared with interferon low-dose cytarabine for newly diagnosed chronic-phase chronic myeloid leukemia. N Engl J Med 2003; 348: 994-1004.
2. Hehlmann R. Current CML therapy: Progress and dilemma. Leukemia 2003; 17: 1010-1012.
3. Kantarjian H, Sawyers C, Hochhaus A, Guilhot F, Schiffer C, Gambacorti-Passerini C et al. International STI571 CML Study Group: hematologic and cytogenetic responses to imatinib mesylate in chronic myelogenous leukemia. N Engl J Med 2002; 346: 645-652.
4. Bergeron A, Bergot E, Vilela G, Ades L, Devergie A, Esperou H et al. Hypersensitivity pneumonitis related to imatinib mesylate. J Clin Oncol 2002; 20: 4271-4272.
5. Rosado MF, Donna E, Ahn YS. Challenging problems in advanced malignancy: Case 3. Imatinib mesylate-induced interstitial pneumonitis. J Clin Oncol 2003; 21: 3171-3173.