Pharmacokinetics, Methionine Depletion, and Antigenicity of Recombinant Methioninase in Primates

Clinical Cancer Research

Volumn 10, Issue 6, 2004, Pages 2131-2138

  Yang, Zhijian ^a   Wang, Junhua ^b   Yoshioka, Takayuki ^c   Li, Baoqiu ^d   Lu, Quan ^b   Li, Shukuan ^a   Sun, Xinghua ^a   Tan, Yuying ^a   Yagi, Shigeo ^a   Frenkel, Eugene P ^e   Hoffman, Robert M ^a,f  

^a ANTICANCER INC   (United States)

^b Kingsley Pharmaceutical Inc   (China)

^c SHIONOGI AND CO LTD   (Japan)

^d J P Pharmaceut Technol Co Ltd   (China)

^e UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^f NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DRUG ANTIBODY; HYDROCORTISONE; IMMUNOGLOBULIN G; METHIONINE; NEUTRALIZING ANTIBODY; RECOMBINANT METHIONINE GAMMA LYASE; RECOMBINANT METHIONINE GAMMA LYASE ANTIBODY; UNCLASSIFIED DRUG;

ADOLESCENT; ALBUMIN BLOOD LEVEL; AMINO ACID BLOOD LEVEL; ANAPHYLACTIC SHOCK; ANIMAL TISSUE; ANTIGENICITY; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DOSE CALCULATION; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG EFFECT; DRUG ELIMINATION; DRUG HALF LIFE; ENZYME ACTIVITY; ERYTHROCYTE COUNT; FOOD INTAKE; HEMOGLOBIN DETERMINATION; LEUKOCYTE COUNT; MACACA; MALE; NONHUMAN; PRIORITY JOURNAL; PROVOCATION TEST; VOMITING; WEIGHT REDUCTION;

ANIMALS; CARBON-SULFUR LYASES; HALF-LIFE; HUMANS; KINETICS; MACACA FASCICULARIS; MALE; METHIONINE; PRIMATES; RECOMBINANT PROTEINS;

EID: 12144288046     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-03-0068     Document Type: Article

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