Antineoplastic Agents 491.1 Synthetic Conversion of Aaptamine to Isoaaptamine, 9-Demethylaaptamine, and 4-Methylaaptamine

Journal of Organic Chemistry

Volumn 69, Issue 7, 2004, Pages 2251-2256

  Pettit, George R ^a   Hoffmann, Holger ^a   Herald, Delbert L ^a   McNulty, James ^a   Murphy, Alison ^a   Higgs, Kerianne C ^a   Hamel, Ernest ^b   Lewin, Nancy E ^c   Pearce, Larry V ^c   Blumberg, Peter M ^c   Pettit, Robin K ^a   Knight, John C ^a  

^a ARIZONA STATE UNIVERSITY   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALKYLATION; AMINES; CELL CULTURE; DERIVATIVES; TUMORS; X RAY ANALYSIS;

CELL GROWTH; CELL LINES;

SYNTHESIS (CHEMICAL);

1H BENZO[DE][1,6] NAPHTHYRIDINE; 4 METHYLAAPTAMINE; 8,9 DIHYDROXY 1H BENZO[DE][1,6]NAPHTHYRIDINE HYDROBROMIDE; 9 NORAAPTAMINE; 9 NORAAPTAMINE HYDROBROMIDE; AAPTAMINE; ANTINEOPLASTIC AGENT; HYDROBROMIC ACID; ISOAAPTAMINE; NAPHTHYRIDINE DERIVATIVE; NATURAL PRODUCT; PROTEIN KINASE C INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIMICROBIAL ACTIVITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CRYSTAL STRUCTURE; DEMETHYLATION; DRUG SYNTHESIS; HUMAN; HUMAN CELL; LYMPHOMA CELL P388F; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; SIGNAL TRANSDUCTION; SPONGE (PORIFERA); X RAY ANALYSIS;

ANIMALS; ANTINEOPLASTIC AGENTS; BACTERIA; CANDIDA ALBICANS; CRYPTOCOCCUS NEOFORMANS; DRUG SCREENING ASSAYS, ANTITUMOR; LEUKEMIA P388; MICE; MICROBIAL SENSITIVITY TESTS; MOLECULAR STRUCTURE; NAPHTHYRIDINES; PORIFERA; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED;

EID: 12144288011     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo0300486     Document Type: Article

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