Evaluation of the Effects of Sulfamethoxazole on Toxoplasma gondii Loads and Stage Conversion in IFN-γ Knockout Mice Using QC-PCR

Microbiology and Immunology

Volumn 48, Issue 3, 2004, Pages 185-193

  Belal, Usama S ^a   Norose, Kazumi ^a   Aosai, Fumie ^a   Mun, Hye Seong ^a   Ahmed, Azza K ^a   Chen, Mei ^a   Mohamed, Rabie M ^a   Piao, Lian Xun ^a   Iwakura, Yoichiro ^b   Yano, Akihiko ^a  

^a CHIBA UNIVERSITY   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

Chemotherapy; Immunocompromised hosts; Interferon gamma; Stage conversion; Sulfamethoxazole; Toxoplasma gondii

Indexed keywords

RECOMBINANT GAMMA INTERFERON; SULFAMETHOXAZOLE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRADYZOITE; BRAIN TISSUE; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DRUG EFFECT; EVALUATION; FEMALE; HEART; IMMUNE DEFICIENCY; KIDNEY; KNOCKOUT MOUSE; LIFE CYCLE; MESENTERY LYMPH NODE; MOUSE; MOUTH INFECTION; NONHUMAN; PARASITE DEVELOPMENT; POLYMERASE CHAIN REACTION; POPULATION ABUNDANCE; QUANTITATIVE ANALYSIS; QUANTITATIVE COMPETITIVE POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SKELETAL MUSCLE; SKIN CULTURE; SMALL INTESTINE; SPLEEN; TACHYZOITE; TONGUE; TOXOPLASMA GONDII;

ANIMALIA; PROTOZOA; TOXOPLASMA GONDII;

EID: 12144286431     PISSN: 03855600     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1348-0421.2004.tb03504.x     Document Type: Article

References (38)

1. Bergin, C., Murphy, M., Lyons, D., Gaffney, E., and Mulcahy, F.M. 1992. Toxoplasma pneumonitis: fatal presentation of disseminated toxoplasmosis in a patient with AIDS. Eur. Respir. J. 5: 1018-1020.
2. Bertoli, F., Espino, M., Arosemena, J.R., Fishback, J.L., and Frenkel, J.K. 1995. A spectrum in the pathology of toxoplasmosis in patients with acquired immunodeficiency syndrome. Arch. Pathol. Lab. Med. 119: 214-224.
3. Bohne, W., Gross, U., Ferguson, D.J., and Heesemann, J. 1995. Cloning and characterization of a bradyzoite specifically expressed gene (Hsp30/bag1) of Toxoplasma gondii related to genes encoding small heat-shock proteins of plants. Mol. Microbiol. 16: 1221-1230.
4. Burg, J.L., Perelman, D., Kasper, L.H., Ware, P.L., and Boothroyd, J.C. 1988. Molecular analysis of the gene encoding the major surface antigen of Toxoplasma gondii. J. Immunol. 141: 3584-3591.
5. Caramello, P., Brancale, T., Forno, B., Lucchini, A., Pollono, A.M., Ullio, A., Gioannini, P., Viano, I., and Tonso, E. 1995. Relapse of Toxoplasma encephalitis and susceptibility to pyrimethamine: lack of evidence of treatment-induced resistance. Antimicrob. Agents Chemother. 39: 2371-2372.
6. Dollfus, H., Dureau, P., Hennequin, C., Uteza, Y., Bron, A., and Dufier, J.L. 1998. Congenital toxoplasma chorioretinitis transmitted by preconceptionally immune women. Br. J. Ophthalmol. 82: 1444-1448.
7. Dubey, J.P. 1998. Advances in the life cycle of Toxoplasma gondii. Int. J. Parasitol. 28: 1019-1024.
8. Dumas, J.-L., Pizzolato, G., and Pechere, J.-C. 1999. Evaluation of trimethoprim and sulphamethoxazole as monotherapy or in combination in the management of toxoplasmosis in murine models. Int. J. Antimicrob. Agents 13: 35-39.
9. Gallino, A., Maggiorini, M., Kiowski, W., Martin, X., Wunderli, W., Schneider, J., Turina, M., and Follath, F. 1996. Toxoplasmosis in heart transplant recipients. Eur. J. Clin. Microbiol. Infect. Dis. 15: 389-393.
10. + T lymphocytes is required to reactivate chronic infection with Toxoplasma gondii. J. Immunol. 149: 175-180.
11. Giordano, L.F.C., Lasmar, E.P., Tavora, E.R.F., and Lasmar, M.F. 2002. Toxoplasmosis transmitted via kidney allograft: case report and review. Transplant. Proc. 34: 498-499.
12. Kamei, K., Sato, K., and Tsunematsu, Y. 1976. A strain of mouse highly susceptible to Toxoplasma. J. Parasitol. 62: 714.
13. Kang, H., and Suzuki, Y. 2001. Requirement of non-T cells that produce gamma interferon for prevention of reactivation of Toxoplasma gondii infection in the brain. Infect. Immun. 69: 2920-2927.
14. Kobayashi, M., Aosai, F., Hata, H., Mun, H.-S., Tarawa, Y., Iwakura, Y., and Yano, A. 1999. Toxoplasma gondii: difference of invasion into tissue of digestive organs between susceptible and resistant strain and influence of IFN-γ in mice inoculated with the cysts perorally. J. Parasitol. 85: 973-975.
15. Koppe, J.G., Loewer-Sieger, D.H., and De Roever-Bonnet, H. 1986. Results of 20-year follow-up of congenital toxoplasmosis. Lancet I: 254-255.
16. Luft, B.J., and Remington, J.S. 1988. Toxoplasmic encephalitis. J. Infect. Dis. 157: 1-5.
17. Luft, B.J., and Remington, J.S. 1992. Toxoplasmic encephalitis in AIDS. Clin. Infect. Dis. 15 Suppl. (1): 211-222.
18. Luft, B.J., Hafner, R., Korzun, A.H., Leport, C., Antoniskis, D., Bosler, E.M., Bourland, D.D., Uttamchandani, R., Fuhrer, J., Jacobson, J., Morlat, P., Vilde, J.-L., Remington, J.S., and Members of the ACTG 077p/ANRS 009 Study Team. 1993. Toxoplasmic encephalitis in patients with the acquired immunodeficiency syndrome. N. Engl. J. Med. 329: 995-1000.
19. Luo, W.-T., Seki, T., Yamashita, K., Aosai, F., Ueda, M., and Yano, A. 1995. Quantitative detection of Toxoplasma gondii by competitive polymerase chain reaction of the surface specific antigen gene-1. Jpn. J. Parasitol. 44: 183-190.
20. Luo, W., Aosai, F., Ueda, M., Yamashita, K., Shimizu, K., Sekiya, S., and Yano, A. 1997. Kinetics in parasite abundance in susceptible and resistant mice infected with an avirulent strain of Toxoplasma gondii by using quantitative competitive PCR. J. Parasitol. 83: 1070-1074.
21. Lyons, R.E., McLeod, R., and Roberts, C.W. 2002. Toxoplasma gondii tachyzoite-bradyzoite interconversion. TRENDS Parasitol. 18: 198-201.
22. Montoya, J.G., Jordan, R., Lingamneni, S., Berry, G.J., and Remington, J.S. 1997. Toxoplasmic myocarditis and polymyositis in patients with acute acquired toxoplasmosis diagnosed during life. Clin. Infect. Dis. 24: 676-683.
23. Moskowitz, L., Hensley, G.T., Chan, J.C., and Adams, K. 1985. Immediate causes of death in acquired immunodeficiency syndrome. Arch. Pathol. Lab. Med. 109: 35-738.
24. Mun, H.-S., Aosai, F., and Yano, A. 1999. Role of Toxoplasma gondii HSP70 and Toxoplasma gondii HSP 30/bag1 in antibody formation and prophylactic immunity in mice experimentally infected with Toxoplasma gondii. Microbiol. Immunol. 43: 471-479.
25. Mun, H.-S., Aosai, F., Norose, K., Chen, M., Hata, H., Tagawa, Y., Iwakura, Y., Byun, D.-S., and Yano, A. 2000. Toxoplasma gondii HSP70 as a danger signal in Toxoplasma gondii-infected mice. Cell Stress Chaperones 5: 328-335.
26. Norose, K., Mun, H.S., Aosai, F., Chen, M., Hata, H., Tagawa, Y., Iwakura, Y., and Yano, A. 2001. Organ infectivity of Toxoplasma gondii in interferon-γ knockout mice. J. Parasitol. 87: 447-452.
27. Oksanen, A., Gustafsson, K., Lunden, A., Dubey, J.P., Thulliez, P., and Uggla, A. 1996. Experimental Toxoplasma gondii infection leading to fatal enteritis in reindeer (Rangifer tarandus) J. Parasitol. 82: 843-845.
28. Orr, K.E., Gould, F.K., Short, G., Dark, J.H., Hilton, C.J., Corris, P.A., and Freeman, R. 1994. Outcome of Toxoplasma gondii mismatches in heart transplant recipients over a period of 8 years. J. Infect. 29: 249-253.
29. Piketty, C., Derouin, F., Rouveix, B., and Pocidalo, J.-J. 1990. In vivo assessment of antimicrobial agents against Toxoplasma gondii by quantification of parasites in the blood, lungs, and brain of infected mice. Antimicrob. Agents Chemother. 34: 1467-1472.
30. Pomeroy, C., and Filice, G.A. 1992. Pulmonary toxoplasmosis: a review. Clin. Infect. Dis. 14: 863-870.
31. Ryning, F.W., McLeod, R., Maddox, J.C., Hunt, S., and Remington, J.S. 1979. Probable transmission of Toxoplasma gondii by organ transplantation. Ann. Intern. Med. 90: 47-49.
32. Sluiters, J.F., Balk, A.H., Essed, C.E., Mochtar, B., Weimar, W., Simoons, M.L., and Jzerman, E.P. 1989. Indirect enzyme-linked immunosorbent assay for immunoglobulin G and our immunoassays for immunoglobulin M to Toxoplasma gondii in a series of heart transplant recipients. J. Clin. Microbiol. 27: 529-535.
33. Suzuki, Y., Conley, F.K., and Remington, J.S. 1989. Importance of endogenous IFN-γ for prevention of toxoplasmic encephalitis in mice. J. Immunol. 143: 2045-2050.
34. Suzuki, Y., Kang, H., Parmley, S., Lim, S., and Park, D. 2000. Induction of tumor necrosis factor-α and inducible nitric oxide synthase fails to prevent toxoplasmic encephalitis in the absence of interferon-γ in genetically resistant BALB/c mice. Microbes Infect. 2: 455-462.
35. -/- mice. J. Immunol. 159: 1418-1428.
36. Van de Ven, E.S., Galama, J., Vree, T., Camps, W., Baars, I., Eskes Meuwissen, J., and Melchers, W. 1995. Study of treatment of congenital Toxoplasma gondii infection in rhesus monkeys with pyrimethamine and Sulfadiazine. Antimicrob. Agents Chemother. 39: 137-144.
37. Wreghitt, T.G., Hakim, M., Gray, J.J., Balfour, A.H., Stovin, P.G., Stewart, S., Scott, J., English, T.A., and Wallwork, J. 1989. Toxoplasmosis in heart and heart and lung transplant recipients. J. Clin. Pathol. 42: 194-199.
38. Yano, A., Mun, H.-S., Chen, M., Norose, K., Hata, K., Kobayashi, M., Aosai, F., and Iwakura, Y. 2002. Roles of IFN-γ on stage conversion of an obligate intracellular protozoan parasite, Toxoplasma gondii. Int. Rev. Immunol. 21: 405-421.