PknH, a transmembrane Hank's type serine/threonine kinase from Mycobacterium tuberculosis is differentially expressed under stress conditions

FEMS Microbiology Letters

Volumn 233, Issue 1, 2004, Pages 107-113

  Sharma, Kirti ^a,b   Chandra, Harish ^a   Gupta, Pradeep K ^a,b   Pathak, Monika ^a   Narayan, Azeet ^a   Meena, Laxman S ^a   D'Souza, Rochelle C J ^a   Chopra, Puneet ^a   Ramachandran, S ^a   Singh, Yogendra ^a  

^a CSIR INSTITUTE OF GENOMICS AND INTEGRATIVE BIOLOGY   (India)

^b UNIVERSITY OF DELHI   (India)

Author keywords

Hank's type; Mycobacterium; PknH; Ser Thr kinase; Stress; Tuberculosis

Indexed keywords

1 (5 ISOQUINOLINESULFONYL) 2 METHYLPIPERAZINE; BACTERIAL ENZYME; GLUTATHIONE TRANSFERASE; HISTONE; MEMBRANE PROTEIN; MYELIN; PHOSPHOTRANSFERASE; PHOSPHOTRANSFERASE INHIBITOR; PROTEIN; PROTEIN PKNH; PROTEIN SERINE THREONINE KINASE; SERINE; STAUROSPORINE; THREONINE PROTEINASE; UNCLASSIFIED DRUG;

ADAPTATION; ALKALINITY; ARTICLE; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; ENZYME SUBSTRATE; ESCHERICHIA COLI; HEAT SHOCK; MOLECULAR CLONING; MYCOBACTERIUM; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; STRESS; TRANSCRIPTION INITIATION;

1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE; ACIDS; ADAPTATION, PHYSIOLOGICAL; BACTERIAL PROTEINS; CLONING, MOLECULAR; ENZYME INHIBITORS; ESCHERICHIA COLI; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, BACTERIAL; HEAT; HISTONES; MEMBRANE PROTEINS; MYCOBACTERIUM TUBERCULOSIS; MYELIN BASIC PROTEINS; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; RECOMBINANT FUSION PROTEINS; SIGNAL TRANSDUCTION; STAUROSPORINE;

BACTERIA (MICROORGANISMS); MYCOBACTERIUM; MYCOBACTERIUM TUBERCULOSIS; MYCOBACTERIUM TUBERCULOSIS COMPLEX; PROKARYOTA;

EID: 12144285650     PISSN: 03781097     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.femsle.2004.01.045     Document Type: Article

References (27)

1. Krebs E.G., Fischer E.H. The phosphorylase b to a converting enzyme of rabbit skeletal muscle, 1956. Biochim. Biophys. Acta. 1000:1989;302-309.
2. Matsumoto A., Hong S.K., Ishizuka H., Horinouchi S., Beppu T. Phosphorylation of the AfsR protein involved in secondary metabolism in Streptomyces species by a eukaryotic-type protein kinase. Gene. 146:1994;47-56.
3. Han G., Zhang C.C. On the origin of Ser/Thr kinases in a prokaryote. FEMS Microbiol Lett. 200:2001;79-84.
4. Madec E., Laszkiewicz A., Iwanicki A., Obuchowski M., Seror S. Characterization of a membrane-linked Ser/Thr protein kinase in Bacillus subtilis, implicated in developmental processes. Mol. Microbiol. 46:2002;571-586.
5. Inouye S., Jain R., Ueki T., Nariya H., Xu C.Y., Hsu M.Y., Fernandez-Luque B.A., Munoz-Dorado J., Farez-Vidal E., Inouye M. A large family of eukaryotic-like protein Ser/Thr kinases of Myxococcus xanthus, a developmental bacterium. Microb. Comp. Genomics. 5:2000;103-120.
6. Hanks S., Quinn A.M. Protein kinase catalytic domain sequence database: identification of conserved features of primary structure and classification of family members. Methods Enzymol. 200:1991;38-62.
7. Bakal C.J., Davies J.E. No longer an exclusive club: eukaryotic signalling domains in bacteria. Trends Cell Biol. 10:2000;32-38.
8. Av-Gay Y., Everett M. The eukaryotic-like Ser/Thr protein kinases of Mycobacterium tuberculosis. Trends Microbiol. 8:2000;238-244.
9. Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C., Harris D., Gordon S.V., Eiglmeier K., Gas S., Barry III C.E., Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T., Connor R., Davies R., Devlin K., Feltwell T.S., Gentles N., Hamlin S., Holroyd T., Hornsby K., Jagels, Krogh A., Mclean J., Moule J., Murphy L., Oliver K., Osborne J., Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton J., Squares R., Squares S., Sulston J.E., Taylor K., Whitehead S., Barrell B.G. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Nature. 393:1998;537-544.
10. Young T.A., Delagoutte B., Endrizzi J.A., Falick A.M., Alber T. Structure of Mycobacterium tuberculosis PknB supports a universal activation mechanism for Ser/Thr protein kinases. Nat. Struct. Biol. 10:2003;168-174.
11. Peirs P., De Wit L., Braibant M., Huygen K., Content J. A serine/threonine protein kinase from Mycobacterium tuberculosis. Eur. J. Biochem. 244:1997;604-612.
12. Av-Gay Y., Jamil S., Drews S.J. Expression and characterization of the Mycobacterium tuberculosis serine/threonine protein kinase PknB. Infect. Immun. 67:1999;5676-5682.
13. Koul A., Choidas A., Tyagi A.K., Drlica K., Singh Y., Ullrich A. Serine/threonine protein kinases PknF and PknG of Mycobacterium tuberculosis: characterization and localization. Microbiology. 147:2001;2307-2314.
14. Chaba R., Raje M., Chakraborti P.K. Evidence that a eukaryotic-type serine/threonine protein kinase from Mycobacterium tuberculosis regulates morphological changes associated with cell division. Eur. J. Biochem. 269:2002;1078-1085.
15. Molle V., Girard-Blanc C., Kremer L., Doublet P., Cozzone A.J., Prost J.F. Protein PknE, a novel transmembrane eukaryotic-like serine/threonine kinase from Mycobacterium tuberculosis. Biochem. Biophys. Res. Commun. 308:2003;820-825.
16. ′ motif in the interaction of mycobacterial RNA polymerase with a promoter of 'extended -10' class FEMS Microbiol. Lett. 225:2003;75-83.
17. Dahl J.L., Wei J., Moulder J.W., Laal S., Friedman R.L. Subcellular localization of the intracellular survival-enhancing Eis protein of Mycobacterium tuberculosis. Infect. Immun. 69:2001;4295-4302.
18. Drews S.J., Hung F., Av-Gay Y. A protein kinase inhibitor as an antimycobacterial agent. FEMS Microbiol Lett. 205:2001;369-374.
19. Hakansson S., Galyov E.E., Rosqvist R., Wolf-Watz H. The Yersinia YpkA Ser/Thr kinase is translocated and subsequently targeted to the inner surface of the HeLa cell plasma membrane. Mol. Microbiol. 20:1996;593-603.
20. Chow K., Ng D., Strokes R., Johnson P. Protein tyrosine phosphorylation in Mycobacterium smegmatis. FEMS Microbiol. Lett. 124:1994;203-208.
21. Lamichhane G., Zignol M., Blades N.J., Geiman D.E., Dougherty A., Grosset J., Broman K.W., Bishai W.R. A postgenomic method for predicting essential genes at subsaturation levels of mutagenesis: application to Mycobacterium tuberculosis. Proc. Natl. Acad. Sci. U S A. 100:2003;7213-7218.
22. Williamson M.P. The structure and function of proline-rich regions in proteins. Biochem. J. 297:1994;249-260.
23. Nadvornik R., Vomastek T., Janecek J., Technikova Z., Branny P. Pkg2, a novel transmembrane protein Ser/Thr kinase of Streptomyces granaticolor. J. Bacteriol. 181:1999;15-23.
24. Umeyama T., Lee P.C., Horinouchi S. Protein serine/threonine kinases in signal transduction for secondary metabolism and morphogenesis in Streptomyces. Appl. Microbiol. Biotechnol. 59:2002;419-425.
25. B in response to environmental stress J. Bacteriol. 178:1996;3846-3853.
26. Iordanov M.S., Magun B.E. Different mechanisms of c-Jun NH(2)-terminal kinase-1 (JNK1) activation by ultraviolet-B radiation and by oxidative stressors. J. Biol. Chem. 274:1999;25801-25806.
27. Cowley S.C., Av-Gay Y. Promoter activity and protein localization in Mycobacterium spp. using green fluorescent protein. Gene. 264:2001;225-231.