A new bifunctional chelating agent conjugated with monoclonal antibody and labelled with technetium-99m for targeted scintigraphy: 6-(4-isothiocyanatobenzyl)-5,7-dioxo-1,11-(carboxymethyl)- 1,4,8,11-tetraazacyclotridecane

Journal of Drug Targeting

Volumn 12, Issue 9-10, 2004, Pages 559-567

  Mishra, Anil Kumar ^a   Panwar, Puja ^a,b   Hosono, Makoto ^c   Chuttani, Krishna ^a   Mishra, Pushpa ^a   Sharma, Rakesh Kumar ^a   Chatal, Jean Francois ^d  

^a INSTITUTE OF NUCLEAR MEDICINE AND ALLIED SCIENCES   (India)

^b UNIVERSITY OF DELHI   (India)

^c KINKI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^d INSERM   (France)

Author keywords

Bifunctional chelating agent; CEA; EGF receptor; Radioimmunoconjugate; Technetium 99m

Indexed keywords

6 (4 ISOTHIOCYANATOBENZYL) 5,7 DIOXO 1,11 (CARBOXYMETHYL) 1,4,8,11 TETRAAZACYCLOTRIDECANE CARCINOEMBRYONIC ANTIBODY TC 99M CONJUGATE; 6 (4 ISOTHIOCYANATOBENZYL) 5,7 DIOXO 1,11 (CARBOXYMETHYL) 1,4,8,11 TETRAAZACYCLOTRIDECANE EPIDERMAL GROWTH FACTOR RECEPTOR ANTIBODY TC 99M CONJUGATE; BROMOACETIC ACID; MALONIC ACID DERIVATIVE; RADIOPHARMACEUTICAL AGENT; SODIUM DIHYDROGEN PHOSPHATE; TRIENTINE; UNCLASSIFIED DRUG;

ALKYLATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY LABELING; ARTICLE; BREAST CARCINOMA; CONTROLLED STUDY; DRUG BINDING; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG CONJUGATION; DRUG DISTRIBUTION; DRUG PURIFICATION; DRUG SYNTHESIS; DRUG TARGETING; DRUG TISSUE LEVEL; DRUG UPTAKE; EHRLICH ASCITES TUMOR; GEL PERMEATION CHROMATOGRAPHY; GLIOBLASTOMA; HUMAN; IMMUNOREACTIVITY; IMMUNOSCINTIGRAPHY; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; NUDE MOUSE; PH; PRIORITY JOURNAL; RABBIT; RAT; TUMOR LOCALIZATION; TUMOR XENOGRAFT;

ALKANES; ANIMALS; ANTIBODIES, MONOCLONAL; CHELATING AGENTS; DRUG DELIVERY SYSTEMS; HUMANS; MICE; MICE, INBRED BALB C; MICE, NUDE; RADIONUCLIDE IMAGING; RATS; RATS, SPRAGUE-DAWLEY; STAINING AND LABELING; TECHNETIUM; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 11944270959     PISSN: 1061186X     EISSN: None     Source Type: Journal    
DOI: 10.1080/10611860400010671     Document Type: Article

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