Ruthenium-catalyzed addition reaction of alcohols across olefins

Synlett

Volumn , Issue 1, 2005, Pages 179-181

  Oe, Yohei ^a   Ohta, Tetsuo ^a   Ito, Yoshihiko ^a  

^a DOSHISHA UNIVERSITY   (Japan)

Author keywords

Addition reactions; Alcohols; Alkenes; Ethers; Ruthenium

Indexed keywords

ALCOHOL; ALKENE; PHENETHYL ALCOHOL; RUTHENIUM; TOLUENE;

ADDITION REACTION; AMINATION; ARTICLE; CATALYSIS; ELIMINATION REACTION; HYDROBORATION; HYDROSILYLATION; MARKOVNIKOV ADDITION; REPRODUCIBILITY; STEREOCHEMISTRY; TEMPERATURE DEPENDENCE;

EID: 11844288364     PISSN: 09365214     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2004-836058     Document Type: Article

References (13)

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13. 3P) (11 mg, 0.02 mmol) was dissolved in toluene (2 mL) and the solution was heated to 85 °C. After 15 min, AgOTf(11.5 mg, 0.045 mmol) was added and stirred at 85 °C for 3 h. The reaction mixture was cooled to r.t. 2-Phenylethanol (1, 122 mg, 1.0 mmol) and styrene (2a, 260 mg, 2.5 mmol) were added. The reaction mixture was heated to 70 °C and stirred for 48 h. The crude product was purified by silica gel chromatography (hexane-EtOAc = 10:1), yielding product 3a (187 mg, 83%).