Cross-linking vasomotor tone and vascular remodeling: A novel function for tissue transglutaminase?

Circulation Research

Volumn 96, Issue 1, 2005, Pages 9-11

  Langille, B Lowell ^a,b   Dajnowiec, Dorota ^a  

^a UNIVERSITY OF TORONTO   (Canada)

^b TORONTO GENERAL HOSPITAL   (Canada)

Author keywords

Extracellular matrix; Fibronectin; G protein; Nitric oxide

Indexed keywords

BETA INTEGRIN; GELATINASE A; MATRIX METALLOPROTEINASE 14; MATRIX PROTEIN; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE;

ARTERY CONSTRICTION; BLOOD FLOW VELOCITY; BLOOD VESSEL DIAMETER; EDITORIAL; ENZYME ACTIVITY; HEART MUSCLE TENSION; HEART VENTRICLE REMODELING; MUSCLE CONTRACTILITY; MUSCLE FORCE; PRIORITY JOURNAL; PROTEIN CROSS LINKING; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; SHEAR STRESS;

ANIMALS; CELL SIZE; CROSS-LINKING REAGENTS; CYTOSKELETON; ENZYME INDUCTION; EXTRACELLULAR MATRIX; EXTRACELLULAR MATRIX PROTEINS; GENE EXPRESSION REGULATION; GTP-BINDING PROTEINS; HEMORHEOLOGY; HUMANS; NITRIC OXIDE; NOREPINEPHRINE; PROTEIN TRANSPORT; STRESS, MECHANICAL; TRANSGLUTAMINASES; VASCULAR RESISTANCE; VASOCONSTRICTION; VASOCONSTRICTOR AGENTS; VASOMOTOR SYSTEM;

EID: 11844268643     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.0000153883.55971.81     Document Type: Editorial

References (26)

1. Langille BL. Remodelling of developing and mature arteries: endothelium, smooth muscle and matrix. J Cardiovasc Pharmacol. 1993;21:S11-S17.
2. Fleming I, Busse R. Molecular mechanisms involved in the regulation of the endothelial nitric oxide synthase. Am J Physiol. 2003;284:R1-R12.
3. Langille BL, Bendeck MP, Keeley FW. Adaptations of carotid arteries of young and mature rabbits to reduced carotid blood flow. Am J Physiol. 1989;256:H931-H939.
4. Martinez-Lemus LA, Hill MA, Bolz SS, Pohl U, Meininger GA. Acute mechanoadaptation of vascular smooth muscle cells in response to continuous arteriolar vasoconstriction: implications for functional remodeling. FASEB J. 2004;18:708-710.
5. Bakker ENTP, Buus CL, Spaan JAE, Perree J, Ganga A, Rolf TM, Sorop O, Bramsen LH, Mulvany MJ, VanBavel E. Small artery remodeling depends on tissue-type transglutaminase. Circ Res. 2005;96:119-126.
6. Bakker ENTP, Van der Meulen ET, Van den Berg BM, Everts V, Spaan JAE. VanBavel E. Inward remodeling follows chronic vasoconstriction in isolated resistance arteries. J Vasc Res. 2002;39:12-20.
7. Fesus L, Piacentini M. Transglutaminase 2: an enigmatic enzyme with diverse functions. Trends Biochem Sci. 2002;27:534-539.
8. Thomazy V, Fesus L. Differential expression of tissue transglutaminase in human cells. An immunohistochemical study. Cell Tissue Res. 1989; 255:215-224.
9. Haroon ZA, Hettasch JM, Lai TS, Dewhirst MW, Greenberg CS. Tissue transglutaminase is expressed, active, and directly involved in rat dermal wound healing and angiogenesis. FASEB J. 1999;13:1787-1795.
10. Aeschlimann D, Paulsson M. Transglutaminases: protein cross-linking enzymes in tissues and body fluids. Thromb Haemost. 1994;71:402-415.
11. Fesus L, Thomazy V, Autuori F, Ceru MP, Tarcsa E, Piacentini M. Apoptotic hepatocytes become insoluble in detergents and chaotropic agents as a result of transglutaminase action. FEBS Lett. 1989;245:150-154.
12. Langille BL, Brownlee RD. Arterial adaptations to altered blood flow. Can J Physiol Pharmacol. 1991;69:978-983.
13. Keeley FW. Dynamic responses of collagen and elastin to vessel wall perturbation. In: Gotlieb AI, Langille BL, Fedoroff S, eds. Atherosclerosis: Cellular and Molecular Interactions in the Artery Wall. Plenum Press, New York; 1991:101-114.
14. h: a GTP-binding protein with transglutaminase activity and receptor signaling function. Science. 1994;264:1593-1596.
15. Somlyo AP, Somlyo AV. Signal transduction by G-proteins, Rho-kinase and protein phosphatase to smooth muscle and non-muscle myosin II. J Physiol. 2000;522.2:177-185.
16. Peng X, Zhang Y, Zhang H, Graner S, Williams JF, Levitt ML, Lokshin A. Interaction of tissue transglutaminase with nuclear transport protein importin-alpha3. FEBS Lett. 1999;446:35-39.
17. Ballestar E, Boix-Chornet M, Franco L. Conformational changes in the nucleosome followed by the selective accessibility of histone glutamines in the transglutaminase reaction: effects of ionic strength. Biochemistry. 2001;40:1922-1929.
18. Akimov SS, Belkin AM. Cell-surface transglutaminase promotes fibronectin assembly via interaction with the gelatin-binding domain of fibronectin: a role in TGF beta-dependent matrix deposition. J Cell Sci. 2001;114:2989-3000.
19. Balklava Z, Verderio E, Collighan R, Gross S, Adams J, Griffin M. Analysis of tissue transglutaminase function in the migration of swiss 3T3 fibroblasts: the active-state conformation of the enzyme does not affect cell motility but is important for its secretion. J Biol Chem. 2002;277:16567-16575.
20. Deleted in proof.
21. Cho A, Courtman DW, Langille BL. Apoptosis (programmed cell death) in arteries of the neonatal lamb. Circ Res. 1995;76:168-175.
22. Rudic RD, Shesely EG, Maeda N, Smithies O, Segal SS, Sessa WC. Direct evidence for the importance of endothelium-derived nitric oxide in vascular remodeling. J Clin Invest. 1998;101:731-736.
23. Lai TS, Hausladen A, Slaughter TF, Eu JP, Stamler JS, Greenberg CS, Calcium regulates S-nitrosylation, denitrosylation, and activity of tissue transglutaminase. Biochemistry. 2001;40:4904-4910.
24. Bernassola F, Rossi A, Melino G. Regulation of transglutaminases by nitric oxide. Ann N Y Acad Sci. 1999;887:83-91.
25. Bassiouny HS, Song RH, Hong XF, Singh A, Kocharyan H, Glagov S. Flow regulation of 72-kD collagenase IV (MMP-2) after experimental arterial injury. Circulation. 1998;98:157-163.
26. Belkin AM, Zemskov EA, Hang J, Akimov SS, Sikora S, Strongin AY. Cell-surface-associated tissue transglutaminase is a target of MMP-2 proteolysis. Biochemistry. 2004;43:11760-11769.