Validation and implementation of a method for determination of bryostatin 1 in human plasma by using liquid chromatography/tandem mass spectrometry

Analytical Biochemistry

Volumn 337, Issue 1, 2005, Pages 143-148

  Zhao, Ming ^a   Rudek, Michelle A ^a   He, Ping ^a   Smith, B Douglas ^a   Baker, Sharyn D ^a  

^a JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

Bryostatin 1; LC MS MS; Pharmacokinetics

Indexed keywords

ACETONITRILE; CHLORINE COMPOUNDS; ELECTROSPRAY IONIZATION; LIQUIDS; MASS SPECTROMETRY; PHARMACOKINETICS;

BRYOSTATIN 1; COEFFICIENT OF DETERMINATION; LC/MS/MS; LINEAR CALIBRATION CURVE; LIQUID CHROMATOGRAPHY/TANDEM MASS SPECTROMETRY; LIQUID-LIQUID EXTRACTION; SAMPLE PRETREATMENT; TANDEM MASS SPECTROMETRY;

LIQUID CHROMATOGRAPHY;

ACETONITRILE; BRYOSTATIN 1; CHLORIDE; FORMIC ACID; N BUTYL CHLORIDE; PACLITAXEL; UNCLASSIFIED DRUG; WATER;

ACCURACY; ARTICLE; CALIBRATION; COLUMN CHROMATOGRAPHY; DRUG DETERMINATION; DRUG STRUCTURE; ELECTROSPRAY; LIQUID CHROMATOGRAPHY; LIQUID LIQUID EXTRACTION; PLASMA; PRIORITY JOURNAL; TANDEM MASS SPECTROMETRY; VALIDATION PROCESS;

EID: 11844265981     PISSN: 00032697     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ab.2004.10.030     Document Type: Article

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