High prevalence of immunoglobulin A antibody against Epstein-Barr virus capsid antigen in adult patients with lupus with disease flare: Case control studies

Journal of Rheumatology

Volumn 32, Issue 1, 2005, Pages 44-47

  Chen, Chung Jen ^a   Lin, Kuei Hsiang ^b   Lin, Shih Chang ^c   Tsai, Wen Chan ^b   Yen, Jeng Hsien ^b   Chang, Shun Jen ^b   Lu, Sheng Nan ^a   Liu, Hong Wen ^b,c  

^a CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

^b KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^c CATHAY GENERAL HOSPITAL   (Taiwan)

Author keywords

Epstein Barr virus; Flare; Reactivation; Systemic lupus erythematosus

Indexed keywords

IMMUNOGLOBULIN A ANTIBODY; IMMUNOGLOBULIN G ANTIBODY; VIRUS CAPSID ANTIGEN;

ADULT; ARTICLE; ASIA; CLINICAL ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; DISEASE ACTIVITY; DISEASE ASSOCIATION; DISEASE EXACERBATION; DISEASE MARKER; EPSTEIN BARR VIRUS; FEMALE; GENDER; HUMAN; IMMUNOGLOBULIN BLOOD LEVEL; MALE; PREVALENCE; PRIORITY JOURNAL; REMISSION; SYSTEMIC LUPUS ERYTHEMATOSUS; TAIWAN; UNITED STATES; VIRUS INFECTION; VIRUS REACTIVATION;

ADULT; ANTIBODIES, VIRAL; ANTIGENS, VIRAL; CAPSID; CAPSID PROTEINS; CASE-CONTROL STUDIES; EPSTEIN-BARR VIRUS INFECTIONS; FEMALE; HERPESVIRUS 4, HUMAN; HUMANS; IMMUNOGLOBULIN A; IMMUNOGLOBULIN M; LUPUS ERYTHEMATOSUS, SYSTEMIC; MALE; RECURRENCE; SEROEPIDEMIOLOGIC STUDIES; TAIWAN;

EID: 11844260072     PISSN: 0315162X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (19)

1. Ruiz-Irastorza G, Khamashta MA, Castellino G, Hughes GR. Systemic lupus erythematosus. Lancet 2001;357:1027-32.
2. Evans AS, Rothfield NF, Niederman JC. Raised antibody titers to EB virus in systemic lupus erythematosus. Lancet 1971;1:67-8.
3. Stephens DA, Stevens MB, Newell GR, Levine PH, Waggoner DE. Epstein-Barr virus (herpes-type virus) antibodies in connective tissue diseases. Arch Intern Med 1972;130:23-8.
4. Gergely L, Czegledy J, Vaczi L, Gonczol E, Szegedi G, Berenyi E. EBV antibodies in systemic lupus erythematosus. Lancet 1973;1:325-6.
5. Klippel JH, Decker JL, Grimley PM, Evans AS, Rothfield NF. Epstein-Barr virus antibody and lymphocyte tubuloreticular structures in systemic lupus erythematosus. Lancet 1973;2:1057-8.
6. Phillips PE, Hirshaut Y. Epstein-Barr virus antibody levels in systemic lupus erythematosus. Arthritis Rheum 1973;16:97-101.
7. James JA, Kaufman KM, Farris AD, Taylor-Albert E, Lehman TJA, Harley JB. An increased prevalence of Epstein-Barr virus infection in young patients suggests a possible etiology for systemic lupus erythematosus. J Clin Invest 1997;100:3019-26.
8. James JA, Neas BR, Moser KL, et al. Systemic lupus erythematosus in adults is associated with previous Epstein-Barr virus exposure. Arthritis Rheum 2001;44:1122-6.
9. Lynn TC, Tu SM, Kawamura A Jr. Long-term follow-up of IgG and IgA antibodies against viral capsid antigens of Epstein-Barr virus in nasopharyngeal carcinoma. J Laryngol Otol 1985;99:567-72.
10. Bombardier C, Gladman DD, Urowitz MB, Caron D, Chang CH. Derivation of the SLEDAI. A disease activity index for lupus patients. The Committee on Prognosis Studies in SLE. Arthritis Rheum 1992;35:630-40.
11. Gladman DD, Urowitz MB, Kagal A, Hallett D. Accurately describing changes in disease activity in systemic lupus erythematosus. J Rheumatol 2000;27:377-9.
12. Lau CS, Yuen KY, Chan KH, Wong RWS. Lack of evidence of active lytic replication of Epstein-Barr and cytomegaloviruses in patients with systemic lupus erythematosus. Chin Med J 1998;111:660-5.
13. Tsai YT, Chiang BL, Kao YF, Hsieh KH. Detection of Epstein-Barr virus and cytomegalovirus genome in white blood cells from patients with juvenile rheumatoid arthritis and childhood systemic lupus erythematosus. Int Arch Allergy Immunol 1995;106:235-40.
14. James JA, Scofield RH, Harley JB. Lupus humoral autoimmunity after short peptide immunization. Ann NY Acad Sci 1997;815:124-7.
15. James JA, Gross T, Scofield RH, Harley JB. PPPGMRPP immunization generates ant-Sm humoral autoimmunity and induces systemic lupus erythematosus in rabbits. J Exp Med 1995;181:453-61.
16. Sairenji T, Ohnishi E, Inouye S, Kurata T. Induction of interleukin-10 on activation of Epstein-Barr virus in EBV-infected B-cell lines. Viral Immunol 1998;11:221-31.
17. Llorente L, Zou W, Levy Y, et al. Role of interleukin 10 in the B lymphocyte hyperactivity and autoantibody production of human systemic lupus erythematosus. J Exp Med 1995;181:839-44.
18. Feederle R, Kost M, Baumann M, et al. The Epstein-Barr virus lytic program is controlled by the cooperative functions of two transactivators. EMBO J 2000;19:3080-9.
19. Kang I, Quan T, Nolasco H, et al. Defective control of latent Epstein-Barr virus infection in systemic lupus erythematosus. J Immunol 2004;172:1287-94.