Resolution of (±)-ibuprofen using (-)-brucine as a chiral selector by thin layer chromatography

Biomedical Chromatography

Volumn 18, Issue 10, 2004, Pages 838-840

  Bhushan, R ^a   Gupta, Deepak ^a  

^a INDIAN INSTITUTE OF TECHNOLOGY ROORKEE   (India)

Author keywords

( ) brucine; ( ) ibuprofen; Enantiomeric separation; Normal phase TLC

Indexed keywords

ENANTIOMERS; ORGANIC SOLVENTS; SILICA GEL;

(-)-BRUCINE; (±)-IBUPROFEN; CHIRAL SELECTOR; ENANTIOMERIC RESOLUTION; ENANTIOMERIC SEPARATION; NORMAL PHASE; NORMAL PHASE TLC; SILICA GEL PLATES; SOLVENT SYSTEM; THIN-LAYER CHROMATOGRAPHY;

THIN LAYER CHROMATOGRAPHY;

ACETONITRILE; BRUCINE; IBUPROFEN; IODINE; METHANOL; SILICA GEL; SOLVENT; ACETONITRILE DERIVATIVE; DRUG DERIVATIVE; DYES, REAGENTS, INDICATORS, MARKERS AND BUFFERS; NONSTEROID ANTIINFLAMMATORY AGENT; STRYCHNINE;

ARTICLE; CHIRALITY; COLUMN CHROMATOGRAPHY; CONCENTRATION (PARAMETERS); CONCENTRATION RESPONSE; CONTROLLED STUDY; DIASTEREOISOMER; DRUG PURITY; ENANTIOMER; OPTICAL ROTATION; PH; RACEMIC MIXTURE; SEPARATION TECHNIQUE; TEMPERATURE; THIN LAYER CHROMATOGRAPHY; CHEMISTRY; ISOLATION AND PURIFICATION; METHODOLOGY; STEREOISOMERISM;

ACETONITRILES; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CHROMATOGRAPHY, THIN LAYER; HYDROGEN-ION CONCENTRATION; IBUPROFEN; INDICATORS AND REAGENTS; METHANOL; SOLVENTS; STEREOISOMERISM; STRYCHNINE; TEMPERATURE;

EID: 11844254422     PISSN: 02693879     EISSN: None     Source Type: Journal    
DOI: 10.1002/bmc.398     Document Type: Article

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