Evaluation of in vitro/in vivo correlation for three kinds of self-designed sustained-release nitrendipine formulations using deconvolution method

Yaoxue Xuebao

Volumn 39, Issue 9, 2004, Pages 738-741

  Yang, Ming Shi ^a   You, Ben Gang ^a   Yang, Ming Hua ^b   Cun, Dong Mei ^a   Tao, An Jin ^a   Gui, Fu De ^a  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

^b CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Deconvolution method; in vitro in vivo correlation; Nitrendipine; Sustained release formulations

Indexed keywords

NITRENDIPINE;

ANIMAL EXPERIMENT; ARTICLE; BODY WEIGHT; CALCULATION; COMPARATIVE STUDY; CONTROLLED STUDY; CORRELATION ANALYSIS; DOG; DRUG BLOOD LEVEL; DRUG DESIGN; DRUG FORMULATION; DRUG SCREENING; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; SUSTAINED DRUG RELEASE;

ADMINISTRATION, ORAL; ANIMALS; DELAYED-ACTION PREPARATIONS; DOGS; METHYLCELLULOSE; MICROSPHERES; NITRENDIPINE; POWDERS; SILICONE GELS; TECHNOLOGY, PHARMACEUTICAL;

EID: 11444250963     PISSN: 05134870     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (6)

1. Balan G, Timmins P, Greene DS, et al. In vitro-in vivo correlation models for metformin after administration of modified-release oral dosage forms to healthy human volunteers [ J]. J Pharm Sci, 2001,90(8):1176-1185.
2. Yang MS, Cui FD, Yue P, et al. Pharmacokinetics and relative bioavailability of sustained-release nitrendipine capsules in healthy dogs [J]. J Shenyang Pharm Univ, 2003,20(2):84-87.
3. 14C-nitrendipine in healthy volunteers [J]. J Cardiovasc Pharmacol, 1987,9(Suppl 4):S122 -S128.
4. Langenbucher F, Mysicka J. In vitro and in vivo deconvolution assessment of drug release kinetics from oxprenolol oros preparations [J]. Br J Clin Pharmacol, 1985,19:151S-162S.
5. Wagner JG. Do you need a pharmacokinetic method, and if so, which one? [J] J Pharmacokin Biopharm, 1975,3 (6):457-478.
6. Vaughan DP, Nennis M. Mathematical basis of point-area deconvolution method for determining in vivo input functions [J]. J Pharm Sci, 1978,67(5):663-665.