Effect of nano-hydroxyapatite/collagen composite and bone morphogenetic protein-2 on lumbar intertransverse fusion in rabbits

Chinese Journal of Traumatology - English Edition

Volumn 7, Issue 1, 2004, Pages 18-24

  Sun, Tian Sheng ^a   Guan, Kai ^a   Shi, Shi Shan ^a   Zhu, Bing ^a   Zheng, Yong Jun ^a   Cui, Fu Zhai ^b   Zang, Wei ^b   Liao, Su San ^b  

^a CHINESE PLA GENERAL HOSPITAL   (China)

^b TSINGHUA UNIVERSITY   (China)

Author keywords

Bone morphogenetic protein 2; Lumbar vertebrae; Nano hydroxyapatite collagen composite; Spinal fusion

Indexed keywords

BONE MORPHOGENETIC PROTEIN; BONE MORPHOGENETIC PROTEIN 2; COLLAGEN; HYDROXYAPATITE; RECOMBINANT BONE MORPHOGENETIC PROTEIN 2;

ANALYSIS OF VARIANCE; ANIMAL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTHRODESIS; ARTICLE; AUTOGRAFT; BIODEGRADABILITY; BIOMECHANICS; BODY WEIGHT; BONE CONDUCTION; BONE DEVELOPMENT; BONE GRAFT; BONE MATRIX; BONE PROSTHESIS; BONE REGENERATION; CANCELLOUS BONE; CLINICAL OBSERVATION; COMPARATIVE STUDY; COMPOSITE MATERIAL; CONTROLLED STUDY; DISEASE MODEL; DRUG EFFECT; FEMALE; HISTOLOGY; LUMBAR SPINE; LUMBAR VERTEBRA; MEDICAL ASSESSMENT; METHODOLOGY; NEWBORN; NONHUMAN; PALPATION; POSTOPERATIVE PERIOD; PROBABILITY; RABBIT; SENSITIVITY AND SPECIFICITY; SPINE FUSION; SPINE RADIOGRAPHY; STRUCTURE ANALYSIS; TENSILE STRENGTH; TREATMENT OUTCOME;

EID: 1142311629     PISSN: 10081275     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (15)

1. Laurie SW, Kaban LB, Mulliken JB, et al. Donor-site morbidity after harvesting rib and iliac bone. Plast Reconstr Surg 1984;73:933-938.
2. Younger EM, Chapman MW. Morbidity at bone graft donor sites. J Orthop Truama 1989;3:192-195.
3. Lowenstam HA, Weiner S. On biomineralization. 1st ed. New York: Oxford University Press, 1989:35-40.
4. Landis WJ, Song MJ, Leith A, et al. Mineral and organic matrix interaction in normally calcifying tendon visualized in three dimensions by high-voltage electron microscopic tomography and graphic image reconstruction. J Struct Biol 1993;110:39-54.
5. Du C, Cui FZ, Zhang W, et al. Formation of calcium phosphate/collagen composite through mineralization of collagen matrix. J Biomed Mater Res 2000;50:518-527.
6. Wang RZ, Cui FZ, Lu HB, et al. Synthesis of nanophase hydroxyapatite/collagen composite. J Mater Sci Lett 1995;14:490-492.
7. Boden SD, Schimandle JH, Hutton WC, et al. 1995 Volvo Award in basic science: the use of an osteoinductive growth factor for lumbar spinal fusion. Spine 1995; 20: 2626-2644.
8. Tenhuisen KS, Martin RI, Klimkiewicz M, et al. Formation and properties of a synthetic bone composite: hydroxyapatite-collagen. J Biomed Mater Res 1995; 29: 803-810.
9. Flautre B, Pasquier G, Blary MC, et al. Evaluation of hydroxyapatite powder coated with collagen as an injectable bone substitute: microscopic study in rabbit. J Mater Sci Mater Med 1996;7:63-67.
10. Hemmerle J, Leize M, Voegel JC. Long term behaviour of a hydroxyapatite collagen-glycosaminoglycan biomaterial used for oral surgery: a case report. J Mater Sci Mater Med 1995;6:360-366.
11. Hodge AJ, Petruska JA. Recent studies with the electron microscope on ordered aggregates of he tropocollagen molecule. In: Ramachandran GN, ed. Aspects of protein structure. New York: Academic Press, 1989:219-226.
12. Spiro RC, Thompson AY, Poser JW. Spinal fusion with recombinant human growth and differentiation factor-5 combined with a mineralized collagen matrix. Anat Rec 2001; 263:388-395.
13. Emery SE, Fuller DA, Stevenson S. Ceramic anterior spinal fusion. Biologic and biomechanical comparison. Spine 1996;21:2713-2719.
14. Sandhu HS, Kanim LE, Toth JM, et al. Experimental spinal fusion with recombinant human bone morphogenetic protein-2 without decortication of osseous elements. Spine 1997; 22:1171-1180.
15. Sandhu HS, Kanim LE, Kabo JM. Evaluation of rhBMP-2 with an OPLA carrier in a canine posterolateral (transverse process) spinal fusion model. Spine 1995;20:2669-2682.