Diffuse luminance flicker increases blood flow in major retinal arteries and veins

Vision Research

Volumn 44, Issue 8, 2004, Pages 833-838

  Garhofer G ^a,b   Zawinka, C ^a   Resch, H ^a   Huemer, K H ^a,b   Dorner, G T ^a,b   Schmetterer, L ^a,c  

^a UNIVERSITY OF VIENNA   (Austria)

^b UNIVERSITY OF VIENNA   (Austria)

^c Christian Doppler Laboratory for Innovative Optical Imaging and its Translation to Medicine   (Austria)

Author keywords

Flicker stimulation; Human; Neuro vascular coupling; Retinal blood flow

Indexed keywords

ADULT; ANALYZER; ARTICLE; BLOOD FLOW VELOCITY; BLOOD VESSEL DIAMETER; CONTROLLED STUDY; ERYTHROCYTE; FEMALE; HUMAN; HUMAN EXPERIMENT; LASER DOPPLER FLOWMETRY; LUMINANCE; MALE; NORMAL HUMAN; PRIORITY JOURNAL; RETINA ARTERY; RETINA BLOOD FLOW; RETINA BLOOD VESSEL; RETINA VEIN; VELOCITY; VISUAL STIMULATION;

EID: 1142297499     PISSN: 00426989     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.visres.2003.11.013     Document Type: Article

References (23)

1. Ben-nun J. Comparative flow velocity of erythrocytes and leukocytes in feline retinal capillaries. Investigative Ophthalmology and Visual Science. 37(9):1996;1854-1859.
2. Bill A., Sperber G. Control of retinal and choroidal blood flow. Eye. 4:1990;319-325.
3. Buerk D.G., Riva C.E., Cranstoun S.D. Frequency and luminance-dependent blood flow and K+ ion changes during flicker stimuli in cat optic nerve head. Investigative Ophthalmology and Visual Science. 36(11):1995;2216-2227.
4. Buerk D.G., Riva C.E., Cranstoun S.D. Nitric oxide has a vasodilatory role in cat optic nerve head during flicker stimuli. Microvascular Research. 52(1):1996;13-26.
5. Damon D.N., Duling B.R. A comparison between mean blood velocities and center-line red cell velocities as measured with a mechanical image streaking velocitometer. Microvascular Research. 17(3Pt1):1979;330-332.
6. Falsini B., Riva C.E., Logean E. Flicker-evoked changes in human optic nerve blood flow: Relationship with retinal neural activity. Investigative Ophthalmology and Visual Science. 43(7):2002;2309-2316.
7. Formaz F., Riva C., Geiser M. Diffuse luminance flicker increases retinal vessel diameter in humans. Current Eye Research. 16:1997;1252-1257.
8. Fuchsjager-Mayrl G., Malec M., Polska E., Jilma B., Wolzt M., Schmetterer L. Effects of granulocyte colony stimulating factor on retinal leukocyte and erythrocyte flux in the human retina. Investigative Ophthalmology and Visual Science. 43(5):2002;1520-1524.
9. Garhofer G., Huemer K.H., Zawinka C., Schmetterer L., Dorner G.T. Influence of diffuse luminance flicker on choroidal and optic nerve head blood flow. Current Eye Research. 24(2):2002;109-113.
10. Ito H., Takahashi K., Hatazawa J., Kim S.G., Kanno I. Changes in human regional cerebral blood flow and cerebral blood volume during visual stimulation measured by positron emission tomography. Journal of Cerebral Blood Flow and Metabolism. 21(5):2001;608-612.
11. Kiryu J., Asrani S., Shahidi M., Mori M., Zeimer R. Local response of the primate retinal microcirculation to increased metabolic demand induced by flicker. Investigative Ophthalmology and Visual Science. 36(7):1995;1240-1246.
12. Michelson G., Patzelt A., Harazny J. Flickering light increases retinal blood flow. Retina. 22(3):2002;336-343.
13. Polak K., Dorner G.T., Kiss B., Polska E., Findl O., Rainer G., Eichler H.G., Schmetterer L. Evaluation of the Zeiss retinal vessel analyser. British Journal of Ophthalmology. 84(11):2000;1285-1290.
14. Polak K., Schmetterer L., Riva C.E. Influence of flicker frequency on flicker induced changes of retinal vessel diameters. Investigative Ophthalmology and Visual Science. 43(8):2002;2721-2726.
15. Riva C.E., Falsini B., Geiser M., Petrig B.L. Optic nerve head blood flow response to flicker-Characteristics and possible mechanisms. Pillunat L., Harris A., Anderson D., Greve E. Current concepts on ocular blood flow in glaucoma. 1999;Kugler Publications, The Hague, Netherlands.
16. Riva C.E., Falsini B., Logean E. Flicker-evoked responses of human optic nerve head blood flow: Luminance versus chromatic modulation. Investigative Ophthalmology and Visual Science. 42(3):2001;756-762.
17. Riva C.E., Grunwald J.E., Sinclair S.H., Petrig B.L. Blood velocity and volumetric flow rate in human retinal vessels. Investigative Ophthalmology and Visual Science. 26(8):1985;1124-1132.
18. Riva C.E., Harino S., Shonat R.D., Petrig B.L. Flicker evoked increase in optic nerve head blood flow in anesthetized cats. Neuroscience Letters. 128(2):1991;291-296.
19. Roy C., Sherington C. On the regulation of the blood supply of the brain. Journal of Physiology. 11:1890;85-108.
20. Scheiner A., Riva C., Kazahaya K., Petrig B. Effect of flicker on macular blood flow assessed by the blue field simulation technique. Investigative Ophthalmology and Visual Science. 35(9):1994;3436-3441.
21. Strenn K., Menapace R., Rainer G., Findl O., Wolzt M., Schmetterer L. Reproducibility and sensitivity of scanning laser Doppler flowmetry during graded changes in PO2. British Journal of Ophthalmology. 81(5):1997;360-364.
22. Wang L., Bill A. Effects of constant and flickering light on retinal metabolism in rabbits. Acta Ophthalmologica Scandinavica. 75(3):1997;227-231.
23. Wang L., Kondo M., Bill A. Glucose metabolism in cat outer retina. Effects of light and hyperoxia. Investigative Ophthalmology and Visual Science. 38:1997;48-55.