Nephrotic syndrome caused by membranous nephropathy: Response to a short course of cyclophosphamide alternating with prednisolone

Internal Medicine

Volumn 43, Issue 1, 2004, Pages 30-34

  Fujimoto, Shouichi ^a   Hara, Seiichirou ^a   Sato, Yuji ^a   Yamada, Kazuhiro ^a   Hisanaga, Shuichi ^a   Eto, Tanenao ^a  

^a UNIVERSITY OF MIYAZAKI   (Japan)

Author keywords

Corticosteroid; Immunosuppressive therapy; Membranous glomerulonephritis; Selectivity index; Urinary IgG

Indexed keywords

ALBUMIN; CHOLESTEROL; CORTICOSTEROID; CREATININE; CYCLOPHOSPHAMIDE; CYTOTOXIC AGENT; IMMUNOGLOBULIN G; PREDNISOLONE;

ADULT; ALBUMIN BLOOD LEVEL; ARTICLE; CHOLESTEROL BLOOD LEVEL; CLINICAL ARTICLE; CLINICAL FEATURE; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DOSE RESPONSE; FEMALE; FOLLOW UP; HUMAN; IMMUNOGLOBULIN BLOOD LEVEL; IMMUNOSUPPRESSIVE TREATMENT; INCIDENCE; KIDNEY FUNCTION; MALE; MEMBRANOUS GLOMERULONEPHRITIS; NEPHROTIC SYNDROME; REMISSION; SHORT COURSE THERAPY; SIDE EFFECT;

BIOPSY, NEEDLE; COHORT STUDIES; CYCLOPHOSPHAMIDE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; DRUG THERAPY, COMBINATION; FEMALE; FOLLOW-UP STUDIES; GLOMERULONEPHRITIS, MEMBRANOUS; HUMANS; IMMUNOHISTOCHEMISTRY; KIDNEY FUNCTION TESTS; MALE; MIDDLE AGED; NEPHROTIC SYNDROME; PREDNISOLONE; PROBABILITY; RETROSPECTIVE STUDIES; RISK ASSESSMENT; SEVERITY OF ILLNESS INDEX; TREATMENT OUTCOME;

EID: 1142287409     PISSN: 09182918     EISSN: None     Source Type: Journal    
DOI: 10.2169/internalmedicine.43.30     Document Type: Article

References (20)

1. Austin HA, Falk RJ. Idiopathic membranous nephropathy. in: Therapy in Nephrology and Hypertension: a companion to Brenner and Rector's The Kidney. Brady HR, Wilcox CA, Eds. WB Saunders, Philadelphia, 1999: 189-198.
2. Muirhead N. Management of idiopathic membranous nephropathy. Evidence-based recommendations. Kidney Int 55 (suppl. 70): S47-S55, 1999.
3. Hogan SL, Muller KE, Jennette JC, Falk RJ. A review of therapeutic studies of idiopathic membranous glomerulopathy. Am J Kidney Dis 25: 862-875, 1995.
4. Imperiale TF, Goldfarb S, Berns JS. Are cytotoxic agents beneficial in idiopathic membranous nephropathy? A meta-analysis of the controlled trials. J Am Soc Nephrol 5: 1553-1558, 1995.
5. Ehrenreich T, Churg J. Pathology of membranous nephropathy. Sommer's Pathology Annual. Vol. II. Appleton-Century-Crofts, New York, 1968: 145-186.
6. Schieppati A, Mosconi L, Perna A, et al. Prognosis of untreated patients with idiopathic membranous nephropathy. N Engl J Med 329: 85-89, 1993.
7. Kibriya MG, Tishkov I, Nikolov D. Immunosuppresive therapy with cyclophosphamide and prednisolone in severe idiopathic membranous nephropathy. Nephrol Dial Transplant 9: 138-143, 1994.
8. Branten AJW, Wetzels JFM. Short- and long-term efficacy of oral cyclophosphamide and steroids in patients with membranous nephropathy and renal insufficiency. Clin Nephrol 56: 1-9, 2001.
9. Ponticelli C, Zucchelli P, Passerini P, et al. A 10-year follow-up of a randomized study with methylprednisolone and chlorambucil in membranous nephropathy. Kidney Int 48: 1600-1604, 1995.
10. Ponticelli C, Altieri P, Scolari F, et al. A randomized study comparing methylprednisolone plus chlorambucil versus methylprednisolone plus cyclophosphamide in idiopathic membranous nephropathy. J Am Soc Nephrol 9: 444-450, 1998.
11. Cattran DC, Appel GB, Hebert LA, et al. Cyclosporin in patients with steroid-resistant membranous nephropathy: A randomized trial. Kidney Int 59: 1484-1490, 2001.
12. Fritsche L, Budde K, Farber L, et al. Treatment of membranous glomerulopathy with cyclosporin A: how much patience is required? Nephrol Dial Transplant 14: 1036-1038, 1999.
13. Glassock RJ. The therapy of idiopathic membranous glomerulonephritis. Semin Nephrol 11: 138-147, 1991.
14. Laluck BJ Jr, Cattran DC. Prognosis after complete remission in adult patients with idiopathic membranous nephropathy. Am J Kidney Dis 33: 1026-1032, 1999.
15. Reichert LJM, Koene RAP, Wetzels JFM. Prognostic factors in idiopathic membranous nephropathy. Am J Kidney Dis 31: 1-11, 1998.
16. 1-microglobulin predicts clinical course better than extent of proteinuria in membranous nephropathy. Am J Kidney Dis 38: 240-248, 2001.
17. Bakoush O, Torffvit O, Rippe B, Tencer J. High proteinuria selectivity index based upon IgM is a strong predictor of poor renal survival in glomerular diseases. Nephrol Dial Transplant 16: 1357-1363, 2001.
18. Cattran DC, Pei Y, Greenwood CM, Ponticelli C, Passerini P, Honkanen E. Validation of a predictive model of idiopathic membranous nephropathy: its clinical and research implications. Kidney Int 51: 901-907, 1997.
19. Torres A, Dominguez-Gil B, Carreno A, et al. Conservative versus immunosuppressive treatment of patients with idiopathic membranous nephropathy. Kidney Int 61: 219-227, 2002.
20. Cattran DC. Idiopathic membranous glomerulonephritis. Kidney Int 59: 1983-1994, 2001.