HPLC- How necessary is it for haemoglobinopathy diagnosis in India?

Indian Journal of Pathology and Microbiology

Volumn 46, Issue 3, 2003, Pages 390-393

  Tyagi, Seema ^a   Saxena, Renu ^a,b   Choudhry, V P ^a  

^a ALL INDIA INSTITUTE OF MEDICAL SCIENCES   (India)

^b INSTITUTE ROTARY CANCER HOSPITAL   (India)

Author keywords

Electrophoresis; Haemoglobinopathies; HPLC; Thalassemia

Indexed keywords

HEMOGLOBIN; HEMOGLOBIN A; HEMOGLOBIN A2; HEMOGLOBIN DELTA CHAIN; HEMOGLOBIN E; HEMOGLOBIN F; HEMOGLOBIN Q; HEMOGLOBIN S; UNCLASSIFIED DRUG;

ADOLESCENT; ADULT; ARTICLE; CATION EXCHANGE; CHILD; FEMALE; GEL ELECTROPHORESIS; HBD IRAN SYNDROME; HBD PUNJAB SYNDROME; HBE SYNDROME; HBQ INDIA SYNDROME; HBS SYNDROME; HEMOGLOBINOPATHY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; INDIA; MAJOR CLINICAL STUDY; MALE; SENSITIVITY AND SPECIFICITY; THALASSEMIA; THALASSEMIA MAJOR;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HEMATOLOGIC TESTS; HEMOGLOBINOPATHIES; HEMOGLOBINS, ABNORMAL; HUMANS; INDIA; THALASSEMIA;

EID: 1142286667     PISSN: 03774929     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (11)

1. Rao VB, Banerjee MK, Shewale LH. Detection of haemoglobin variants for the diagnosis of beta-thalassemia and other haemoglobinopathies using anion exchange high performance liquid chromatography. Indian J Med Res 1996; 104:365-73.
2. Clarke GM, Higgins TN. Laboratory investigation of haemoglobinopathies and thalassemias. Review and update. Clin Chem 2000; 46:1284-90.
3. Cawin MJ, Lappat EJ, Brangle RW. Haemoglobin S-D disease. Ann Intern Med 1966; 64:1.
4. th ed. Edinburgh: Churchill Livingstone, 1995.
5. Bio-Rad VARIANTTM thalassemia short program. Instruction manual, 1999;10.
6. Fucharoen S, Winichagoon P, Wisedpancihkij R. Prenatal and postnatal diagnosis of thalassemias and haemoglobinopathies by HPLC. Clin Chem 1998; 44(4):740-8.
7. Rogers BB, Wessels RA, Ou CN. High-performance liquid chromatography in the diagnosis of hemoglobinopathies and thalassemia. Am J Clin Pathol 1985; 84:5.
8. Ou CN, Regnerud CL. Diagnosis of haemoglobinopathies: Electorphoresis vs HPLC. Clin Chim Acta 2001; 313 (1-2):187-94.
9. Abnormal Haemoglobn candidates. An aid to interpretation. Bio-Rad VARIANTTM Library of abnormal haemoglobins. Catalog No. 270-0259.
10. Kulozik AE, Thein SL, Wainscoat JS. Thalassemia intermedia: interaction of triple- globin gene rearrangement and heterozygous beta thalassemia. Br J Haematol 1987; 66:109-12.
11. Camaschella C, Bertero MT, Serra A. A benign form of thalassemia intermedia may be determined by the interaction of triplicated alpha locus and heterozygous beta thalassemia. Br J Haematol 1987; 66:103-7.