A neurological and hematological syndrome associated with zinc excess and copper deficiency [6]

Journal of Neurology

Volumn 251, Issue 1, 2004, Pages 111-114

  Greenberg, Steven A ^a   Briemberg, Hannah R ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CERULOPLASMIN; COPPER; CYANOCOBALAMIN; GLUTEN; IRON; ZINC;

ADULT; ATAXIA; BLOOD TRANSFUSION; BONE MARROW BIOPSY; CASE REPORT; CELIAC DISEASE; CERULOPLASMIN BLOOD LEVEL; CONSULTATION; COPPER BLOOD LEVEL; COPPER DEFICIENCY; COPPER METABOLISM; DISABILITY; DISEASE ASSOCIATION; ELECTRODIAGNOSIS; FEMALE; FOLLOW UP; GLUTEN FREE DIET; HAND MUSCLE; HEMATOLOGY; HUMAN; IRON THERAPY; LETTER; MICROCYTIC ANEMIA; MOTOR NEURON DISEASE; MUSCLE WEAKNESS; NEUROLOGIC DISEASE; NEUROLOGIC EXAMINATION; NEUTROPENIA; NUCLEAR MAGNETIC RESONANCE IMAGING; PARESTHESIA; PRIORITY JOURNAL; RETICULOCYTOSIS; SPASTIC PARAPLEGIA; SPINAL CORD DISEASE; SPINE; ZINC BLOOD LEVEL; ZINC URINE LEVEL;

ANEMIA; CERULOPLASMIN; COPPER; FEMALE; FOLLOW-UP STUDIES; HEMATOLOGIC DISEASES; HUMANS; MAGNETIC RESONANCE IMAGING; METABOLIC DISEASES; MIDDLE AGED; NERVOUS SYSTEM DISEASES; NEURAL CONDUCTION; NEUTROPENIA; PERIPHERAL NERVES; SPINAL CORD; VITAMIN B 12; ZINC;

EID: 1142273171     PISSN: 03405354     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00415-004-0263-0     Document Type: Letter

References (14)

1. Buchman AL, Keen CL, Vinters HV et al. (1994) Copper deficiency secondary to a copper transport defect: a new copper metabolic disturbance. Metabolism 43:1462-1469
2. Fuji T, Okuno T, Ito M, Kaji M, Mutoh K, Mikawa H, Saida K (1991) Non-Menkes-type copper deficiency with regression, lactic acidosis, and granulocytopenia. Neurology 41:1263-1266
3. Krebs NF (2000) Overview of zinc absorption and excretion in the human gastrointestinal tract. J Nutr 130(5S Suppl):1374S-1377S
4. Kumar A, Jazieh AR (2001) Case report of sideroblastic anemia caused by ingestion of coins. Am J Hematol 66: 126-129
5. Kumar N, Gross JB, Ahlskog E (2003) Myelopathy due to copper deficiency. Neurology 61:273-274
6. Matsushima GK, Morell P (2001) The neurotoxicant, cuprizone, as a model to study demyelination and remyelination in the central nervous system. Brain Pathol 11:107-116
7. Prodan CI, Holland NR, Wisdom PJ, Burstein SA, Bottomley S (2002) CNS demyelination associated with copper deficiency and hyperzincemia. Neurology 59:1453-1456
8. Prodan CI, Holland MB (2000) CNS demyelination from zinc toxicity? Neurology 54:1705-1706
9. Schleper B, Stuerenburg HJ (2001) Copper deficiency-associated myelopathy in a 46-year-old woman. J Neurol 248:705-706
10. Simon SR, Branda RF, Tindle BH, Burns SL (1988) Copper deficiency and sideroblastic anemia associated with zinc ingestion. Am J Hematol 28: 181-183
11. Tamura H, Hirose S, Watanabe O, Arai K, Murakawa M, Matsumura O, Isoda K (1994) Anemia and neutropenia due to copper deficiency in enterai nutrition. J Parenteral Enteral Nutr 18: 185-189
12. Wasa M, Satani M, Tanano H, Nezu R, Takagi Y, Okada (1994) Copper deficiency with pancytopenia during parenteral nutrition. J Parenteral Enterai Nutr 18:190-192
13. Wu ZT, Lin MT, Murong SX, Wang N (2003) Molecular diagnosis and prophylactic therapy for presymptomatic Chinese patients with Wilson disease. Arch Neurol 60:737-741
14. Zidar B, Shadduck R, Zeigler Z, Winkelstein A (1977) Observations on the anemia and neutropenia of human copper deficiency. Am J Hematol 3: 177-185