Efficacy of albendazole against the whipworm Trichuris trichiura - A randomised, controlled trial

South African Medical Journal

Volumn 94, Issue 12, 2004, Pages 972-976

  Adams, V J ^a   Lombard, C J ^a   Dhansay, M A ^a   Markus, M B ^b,c   Fincham, J E ^a  

^a SOUTH AFRICAN MEDICAL RESEARCH COUNCIL   (South Africa)

^b UNIVERSITY OF THE WITWATERSRAND   (South Africa)

^c Biomedical Analysis International   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALBENDAZOLE; PLACEBO;

ADOLESCENT; ARTICLE; ASCARIS; CHILD; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOSE RESPONSE; DRUG DOSE REGIMEN; DRUG EFFICACY; DRUG RESPONSE; FECES ANALYSIS; FEMALE; GEOGRAPHIC DISTRIBUTION; GEOMETRY; HEALTH PROGRAM; HUMAN; MAJOR CLINICAL STUDY; MALE; PARASITE IDENTIFICATION; PARASITOSIS; PUBLIC HEALTH SERVICE; RANDOMIZED CONTROLLED TRIAL; RURAL AREA; SIDE EFFECT; SOUTH AFRICA; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE; TRICHURIS;

ADMINISTRATION, ORAL; ADOLESCENT; ALBENDAZOLE; ANTINEMATODAL AGENTS; CHILD; DOUBLE-BLIND METHOD; DRUG ADMINISTRATION SCHEDULE; DRUG AND NARCOTIC CONTROL; DRUG COSTS; FECES; FEMALE; HUMANS; INCIDENCE; MALE; NEEDS ASSESSMENT; PARASITE EGG COUNT; PRESCRIPTIONS, DRUG; PREVALENCE; SCHOOL HEALTH SERVICES; SOUTH AFRICA; TREATMENT OUTCOME; TRICHURIASIS;

EID: 11344284494     PISSN: 02569574     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

1. Fincham JE, Markus MB, Appleton CC, et al. Complications of worm infestation - serious, costly, predictable and preventable. S Afr Med J 1998; 88: 952-953.
2. Crompton DWT, Montresor A, Nesheim MC, Savioli L, eds. Controlling Disease due to Helminth Infections. Geneva: World Health Organization, 2003.
3. Bowley DMG, Parmar NK, Boffard KD. Burdens of disease in southern Africa. Lancet 2004; 363: 1508.
4. Govindasamy V, Thomson SR. Worms wanted, dead or alive. S Afr Med J 2004; 94: 524-525.
5. Kunii C. It All Started From Worms. The 45-year Record of Japan's Post-World War II National Health and Family Planning Movement Tokyo: The Hoken Kaikan Foundation, 1992.
6. Savioli L, Stansfield S, Bundy DAP, et al. Schistosomiasis and soil-transmitted helminth Infections: forging control efforts. Trans R Soc Trop Med Hyg 2002; 96: 577-579.
7. Awasthi S, Bundy DAP, Savioli L. Helminthic Infections. BMJ 2003; 327: 431-433.
8. Anonymous. The Khayelitsha Task Team - Building Health Partnerships that Work. Cape Town: Medical Research Council, 2001.
9. Fincham JE, Markus MB, Adams VJ, et al. Association of deworming with reduced eosinophilia: implications for HIV/AIDS and co-endemic diseases. S Afr J Sci 2003; 99: 182-184.
10. Jackson TFHG, Epstein SR, Gouws E, Cheetham RF. A comparison of mebendazole and albendazole in treating children with Trichuris trichiura infection in Durban, South Africa. S Afr Med J 1998; 88: 880-883.
11. Taylor M, Jinabhai CC, Couper I, Kleinschmidt I, Jogessar VB. The effect of different anthelmintic treatment regimens combined with iron supplementation on the nutritional status of schoolchildren in KwaZulu-Natal, South Africa: a randomized controlled trial. Trans R Soc Trop Med Hyg 2001; 95: 211-216.
12. Horton J. Albendazole: a broad spectrum anthelminthic for treatment of individuals and populations. Curr Opin Infect Dis 2002; 15: 599-608.
13. Montresor A, Awasthi S, Crompton DWT. Use of benzimidazoles in children younger than 24 months for the treatment of soil-transmitted helminthiasis. Acta Trop 2003; 86: 223-232.
14. Gibbon CJ, ed. South African Medicines Formulary. 6th ed. Cape Town: South African Medical Association, Health and Medical Publishing Group, 2003.
15. Arendse VJ. Treatment and prevention of trichuriasis: efficacy of albendazole in disadvantaged children at Rawsonville Primary School, Western Cape Province, South Africa. MScMedSc thesis, University of Stellenbosch, 2001.
16. Anonymous. Report of the WHO Informal Consultation on Monitoring of Drug Efficacy in the Control of Schistosomiasis and Intestinal Nematodes. Geneva: World Health Organization, 1998.
17. Dickson R, Awasthi S, Williamson P, Demellweek C, Garner P. Effects of treatment for intestinal helminth infection on growth and cognitive performance in children: systematic review of randomised trials. BMJ 2000; 320: 1697-1701.
18. Fincham JE, Markus MB, Adams VJ. Could control of soil-transmitted helminthic Infection influence the HIV/AIDS pandemic? Acta Trop 2003; 86: 315-333.
19. Markus MB. Public health and vaccines - immune responses in developed versus poor countries. S Afr Med J 2003; 93: 834-835.
20. Tristão-Sá R, Ribeiro-Rodrigues R, Johnson LT, Pereira FEL, Dietze R. Intestinal nematodes and pulmonary tuberculosis. Rev Soc Bras Med Trop 2002; 35: 533-535.
21. Elliott AM, Kyosiimire J, Quigley MA, et al. Eosinophilia and progression to active tuberculosis in HIV-1-infected Ugandans. Trans R Soc Trop Med Hyg 2003; 97: 477-480.
22. Robinson TM, Nelson RG, Boyer JD. Parasitic infection and the polarized Th2 immune response can alter a vaccine-induced immune response. DNA Cell Biol 2003; 22: 421-430.