Is topical antifungal therapy effective in the treatment of chronic rhinosinusitis?

Journal of Allergy and Clinical Immunology

Volumn 115, Issue 1, 2005, Pages 123-124

  Bush, Robert K ^a,b  

^a William S Middleton VA Hospital   (United States)

^b WILLIAM S MIDDLETON MEMORIAL VETERANS HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMPHOTERICIN B; ANTIFUNGAL AGENT;

ALTERNARIA; ALTERNARIA ALTERNATA; CHRONIC DISEASE; CHRONIC RHINOSINUSITIS; CLINICAL TRIAL; DOSE RESPONSE; DRUG EFFICACY; EDITORIAL; EOSINOPHILIA; FUNGUS; HUMAN; IMMUNE RESPONSE; PATHOGENESIS; PRIORITY JOURNAL; RHINOSINUSITIS; STATISTICAL SIGNIFICANCE; TREATMENT OUTCOME;

ADMINISTRATION, INTRANASAL; ANTIFUNGAL AGENTS; CHRONIC DISEASE; CLINICAL TRIALS; HUMANS; RHINITIS; SINUSITIS;

EID: 11344284140     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jaci.2004.10.025     Document Type: Editorial

References (13)

1. M.A. Kaliner, J.D. Osguthorpe, P. Fireman, J. Anon, J. Georgitis, and M.L. Davis Sinusitis: bench to bedside: current findings, future directions Otolaryngol Head Neck Surg 116 1997 S1 S20
2. M.S. Benninger, B.J. Ferguson, J.A. Hadley, D.L. Hamilos, M. Jacobs, and D.W. Kennedy Adult chronic rhinosinusitis: definitions, diagnosis, epidemiology, and pathophysiology Otolaryngol Head Neck Surg 129 2003 S1 S32
3. J.U. Ponikau, D.A. Sherris, G.M. Kephart, E.B. Kern, T.A. Gaffey, and J.E. Tarara Features of airway remodeling and eosinophilic inflammation in chronic rhinosinusitis: is the histopathology similar to asthma? J Allergy Clin Immunol 112 2003 877 882
4. D.L. Hamilos, D.Y. Leung, D.P. Huston, A. Kamil, R. Wood, and Q. Hamid GM-CSF, IL-5 and RANTES immunoreactivity and mRNA expression in chronic hyperplastic sinusitis with nasal polyposis (NP) Clin Exp Allergy 28 1998 1145 1152
5. J.U. Ponikau, D.A. Sherris, E.B. Kern, H.A. Homburger, E. Frigas, and T.A. Gaffey The diagnosis and incidence of allergic fungal sinusitis Mayo Clin Proc 74 1999 877 884
6. H. Braun, W. Buzina, K. Freudenschuss, A. Beham, and H. Stammberger "Eosinophilic fungal rhinosinusitis": a common disorder in Europe? Laryngoscope 113 2003 264 269
7. M.J. Taylor, J.U. Ponikau, D.A. Sherris, E.B. Kern, T.A. Gaffey, and G. Kephart Detection of fungal organisms in eosinophilic mucin using a fluorescein-labeled chitin-specific binding protein Otolaryngol Head Neck Surg 127 2002 377 383
8. S. Shin, J.U. Ponikau, D.A. Sherris, D. Kongdon, E. Frigas, and H. Homburger Chronic rhinosinusitis: an enhanced immune response to ubiquitous airborne fungi J Allergy Clin Immunol 114 2004 1369 1375
9. J.U. Ponikau, D.A. Sherris, H. Kita, and E.B. Kern Intranasal antifungal treatment in 51 patients with chronic rhinosinusitis J Allergy Clin Immunol 110 2002 862 866
10. A. Ricchetti, B.N. Landis, A. Maffioli, R. Giger, C. Zeng, and J.S. Lacroix Effect of anti-fungal nasal lavage with amphotericin B on nasal polyposis J Laryngol Otol 116 2002 261 263
11. M. Weschta, D. Rimek, M. Formanek, D. Polzehl, A. Podbielski, and H. Riechelmann Topical antifungal treatment of chronic rhinosinusitis with nasal polyps: a randomized, double-blind clinical trial J Allergy Clin Immunol 113 2004 1122 1128
12. J.U. Ponikau, D.A. Sherris, A. Weaver, and H. Kita Treatment of chronic rhinosinusitis with intranasal amphotericin B: a randomized, placebo-controlled, double-blinded pilot trial J Allergy Clin Immunol 115 2005 125 131
13. S.B. Fritz, J.E. Terrell, E.R. Conner, J.F. Kukowska-Latallo, and J.R. Baker Nasal mucosal gene expression in patients with allergic rhinitis with and without nasal polyps J Allergy Clin Immunol 112 2003 1057 1063