Quantitative determination of clavulanic acid in plasma by HPLC: Application to a pharmacokinetic study

Journal of Liquid Chromatography and Related Technologies

Volumn 28, Issue 1, 2005, Pages 97-107

  Matar, Kamal M ^a   Nazi, Esmail M ^b   El Sayed, Yousry M ^b   Al Yamani, Mohammed J ^b   Al Suwayeh, Saleh A ^b   Al Khamis, Khalil I ^b  

^a KUWAIT UNIVERSITY   (Kuwait)

^b KING SAUD UNIVERSITY   (Saudi Arabia)

Author keywords

Bioavailability bioequivalence studies; Clavulanic acid; Human plasma; Liquid chromatography; Pharmacokinetic study

Indexed keywords

CONCENTRATION (PROCESS); METHANOL; PHARMACOKINETICS; PHOSPHATES; PLASMAS; PROTEINS; STAINLESS STEEL; ULTRAVIOLET DETECTORS;

BIOEQUIVALENCE; FLOW RATES; HIGH PERFORMANCE LIQUID CHROMATOGRAPHIC (HPLC) METHODS; MOBILE PHASES;

LIQUID CHROMATOGRAPHY;

AMOXICILLIN; AMOXICILLIN PLUS CLAVULANIC ACID; BUFFER; CLAVULANIC ACID; IMIDAZOLE DERIVATIVE; KLAVOX; METRONIDAZOLE; PLASMA PROTEIN; POTASSIUM DIHYDROGEN PHOSPHATE; STAINLESS STEEL;

ACCURACY; ADULT; ARTICLE; BIOAVAILABILITY; BIOEQUIVALENCE; CLINICAL TRIAL; CONCENTRATION RESPONSE; CONVALESCENCE; CROSSOVER PROCEDURE; EFFLUENT; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN EXPERIMENT; MALE; MOLECULAR STABILITY; NORMAL HUMAN; PH MEASUREMENT; PRECIPITATION; QUANTITATIVE ANALYSIS; QUANTITATIVE DIAGNOSIS; RADIATION DETECTION; REPRODUCIBILITY; ROOM TEMPERATURE; SENSITIVITY ANALYSIS; ULTRAVIOLET RADIATION; VALIDATION PROCESS;

EID: 11244347658     PISSN: 10826076     EISSN: None     Source Type: Journal    
DOI: 10.1081/JLC-200038602     Document Type: Article

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