Analysis of the milling rate of pharmaceutical powders using the Distinct Element Method (DEM)

Chemical Engineering Science

Volumn 60, Issue 5, 2005, Pages 1441-1448

  Kwan, Chih Chi ^a   Mio, Hiroshi ^b,c   Chen, Yong Qi ^a   Ding, Yu Long ^a   Saito, Fumio ^b   Papadopoulos, Dimitris G ^d   Bentham, A Craig ^d   Ghadiri, Mojtaba ^a  

^a UNIVERSITY OF LEEDS   (United Kingdom)

^b TOHOKU UNIVERSITY   (Japan)

^c KFPT   (Japan)

^d PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United Kingdom)

Author keywords

lactose monohydrate; DEM simulation; Media mill; Microcrystalline cellulose

Indexed keywords

BALL MILLING; COMPUTER SIMULATION; DRUG PRODUCTS; HYDRATES; POWDERS;

DISTINCT ELEMENT METHOD (DEM); MACHINE DYNAMICS; MICROCRYSTALLINE CELLULOSE (MCC);

CELLULOSE;

MILLING;

CELLULOSE; DRUGS; GRINDING; HYDRATES; POWDER; SIMULATION;

EID: 11244326214     PISSN: 00092509     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ces.2004.10.002     Document Type: Article

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