Immunohistochemical study of skin nerve regeneration after toe-to-finger transplantation: Correlations with clinical, quantitative sensory, and electrophysiological evaluations

Acta Neurologica Taiwanica

Volumn 13, Issue 4, 2004, Pages 178-185

  Hsieh, Sung Tsang ^a   Chu, Nai Shin ^b,c  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

^c CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

Author keywords

Electrophysiology; Immunohistochemistry; Nerve regeneration; QST; Toe to finger transplantation

Indexed keywords

ANTIBODY; CELL MARKER; GENE PRODUCT; PROTEIN GENE PRODUCT 9.5; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CLINICAL ARTICLE; CLINICAL FEATURE; CONTROLLED STUDY; CONVALESCENCE; CORRELATION ANALYSIS; DERMIS; DISEASE SEVERITY; ELECTROPHYSIOLOGY; EPIDERMIS; FEMALE; FUNCTION TEST; HAND INJURY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; MEISSNER CORPUSCLE; NERVE REGENERATION; QUANTITATIVE DIAGNOSIS; QUANTITATIVE SENSORY TEST; SKIN; SKIN NERVE; TOE TO FINGER TRANSPLANTATION; TRANSPLANTATION;

ADOLESCENT; ADULT; FEMALE; FINGERS; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; NERVE REGENERATION; SKIN; TOES;

EID: 11244319598     PISSN: 10196099     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. Chu NS. Toe-to-finger transplantation: nerve regeneration, functional transformation, and central perception. Crit Rev Phys Rehabil Med 1998;10:303-17.
2. Chu NS. Perception of transplanted toes following toe-to-finger transplantation. J Clin Exp Neuropsychol 1998;20:599-602.
3. Chu NS. Phantom finger phenomena and the effects of toe-to-finger transplantation. Neurorehabil Neural Repair 2000;14:277-85.
4. Chu NS, Chu EC, Yu JM. Conduction study of digital nerve function recovery following toe-to-digit transplantation and a comparison with digit-to-digit replantation. Muscle Nerve 1995;18:1257-64.
5. Chu NS, Wei FC. Recovery of sensations and somatosensory evoked potentials following toe-to-digit transplantation in man. Muscle Nerve 1995;18:859-66.
6. Chu NS, Wei FC. The time course of recovery in somatosensory evoked potentials and sympathetic skin response after toe-to-finger transplantation. In: Hashimoto I, Kakigi R, eds. Recent Advances in Human Neurophysiology: The 6th International Evoked Potential Symposium in Okazaki. Amsterdam: Elsevier Science, 1998:163-8.
7. Chu NS. Recovery of sympathetic skin responses after digit-to-digit replantation and toe-to-digit transplantation in humans. Ann Neural 1996;40:67-74.
8. Chu NS, Wei FC, Lin CH, et al. Sensory recovery after toe-to-finger transplantation: a three-year observation with quantitative sensory and functional sensibility tests. Acta Neural Taiwan 2002;11:70-84.
9. Hsieh ST. Skin biopsy: a new window on small-fiber sensory neuropathy. Acta Neural Taiwan 2001;10:1-8.
10. Hsieh ST, Lin WM, Chiang HY, et al. Skin innervation and its effects on the epidermis. J Biomed Sci 1997;4:264-8.
11. Hsieh ST, Chiang HY, Lin WM. Pathology of nerve terminal degeneration in the skin. J Neuropathol Exp Neural 2000;59:297-307.
12. Hsieh ST, Choi S, Hauer P, et al. Increased epidermal PGP 9.5 mRNA levels in sensory neuropathies. Ann Neurol 1995;38:304-5.
13. Chiang MC, Lin YH, Pan CL, et al. Cutaneous innervation in chronic inflammatory demyelinating polyneuropathy. Neurology 2002;59:1094-8.
14. Pan CL, Tseng TJ, Lin YH, et al. Cutaneous innervation in Guillain-Barré syndrome: pathology and clinical correlations. Brain 2003;126(Pt 2):386-97.
15. Thomas PK. Clinical aspects of PNS regeneration. Adv Neurol 1988;47:9-29.
16. Gelberman R, Urbaniak JR, Bright DS, et al. Digital sensibility following replantation. J Hand Surg 1978;3:313-9.
17. Poppen NK, McCarroll HR JR, Doyle JR, et al. Recovery of sensibility after suture of digital nerves. J Hand Surg 1979;4:212-25.
18. Zelena J. The fate of Pacinian corpuscles after denervation and regeneration. In: Gorio A, Millesi H, Mingrino S, eds. Posttraumatic Peripheral Nerve Regeneration. New York: Raven Press, 1981:563-71.
19. Önne L. Recovery of sensibility and sudomotor activity in the hand after nerve suture. Acta Chir Scand 1962;Suppl 300:1-69.
20. Mackel R, Kunesch E, Waldhor F, et al. Reinnervation of mechanoreceptors in the human glabrous skin following peripheral nerve repair. Brain Res 1983;268:49-65.
21. Dellon AL. Sensory recovery in replanted digits and transplanted toes: a review. J Reconstr Microsurg 1986;2:123-9.