Bilateral increase of perforated synapses after unilateral dopamine depletion

International Journal of Neuroscience

Volumn 115, Issue 1, 2005, Pages 79-86

  Avila Costa, Marí Rosaa ^a,c   Colín Barenque, Laura ^a   Aley Medina, Patricia ^a   Gutíerrez Valdez, Ana Luisa ^a   Ordoñes Librado, José Luis ^a   Flores Martinez, Erick ^a   Fortoul, Teresa I ^b  

^a UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

^b UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

^c NONE   (Mexico)

Author keywords

6 OHDA; Parkinson disease model; Perforated synapses; Ultrastructure

Indexed keywords

APOMORPHINE; DOPAMINE; OXIDOPAMINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN INJURY; CONTROLLED STUDY; CONVALESCENCE; CORPUS STRIATUM; DOPAMINE RELEASE; LEARNING; MALE; MEMBRANE DAMAGE; MEMORY; NERVE CELL PLASTICITY; NERVOUS SYSTEM; NONHUMAN; RAT; STRUCTURE ANALYSIS; SYNAPTIC MEMBRANE; SYNAPTIC PERFORATION;

ANIMALS; APOMORPHINE; BEHAVIOR, ANIMAL; CORPUS STRIATUM; DOPAMINE; DOPAMINE AGONISTS; FUNCTIONAL LATERALITY; MALE; MICROSCOPY, ELECTRON, TRANSMISSION; NEURONAL PLASTICITY; OXIDOPAMINE; PRESYNAPTIC TERMINALS; RATS; RATS, WISTAR; STEREOTYPED BEHAVIOR; SYMPATHOLYTICS; SYNAPSES;

EID: 11244272103     PISSN: 00207454     EISSN: None     Source Type: Journal    
DOI: 10.1080/00207450490512669     Document Type: Article

References (20)

1. Avila-Costa, M. R., Colín-Barenque, L., Espinosa-Villanueva, J., & Machado-Salas, J. (1998). Degeneración del neuropilo del núcleo caudado en la enfermedad de Parkinson y en el modelo experimental provocado con 6-OHDA: Análisis ultraestructural comparativo. Patología, 36, 297-301.
2. Calverley, R. K. S., & Jones, D. G. A. (1987). Serial-section study of perforated synapses in rat neocortex. Cell Tissue Research, 247, 565-572.
3. Carlin, R. K., & Siekevitz, P. (1983). Plasticity in the central nervous system: Do synapses divide? Proceedings of the National Academy of Sciences, 803517-803521.
4. Fass, B., & Butcher, L. L. (1981). Evidence for a crossed nigrostriatal pathway in rats. Neuroscience Letters, 22. 109-113.
5. Geinisnian, Y., de Toledo-Morrell, L., & Morrell F. (1986). Aged rats need a preserved complement of perforated axospinous synapses per hippocampal neuron to maintain good spatial memory. Brain Research, 398, 266-275.
6. Geinisman, Y., Morrell, F., & de Toledo-Morrell, L. (1987). Axospinous synapses with segmented postsynaptic densities: A morphologically distinct synaptic subtype contributing to the number of profiles of "perforated" synapses visualized in random sections. Brain Research, 423, 179-188.
7. Geinisman, Y., Morrell, F., & de Toledo-Morrell, L. (1992). Increase in the number of axospinous synapses with segmented postsynaptic densities following hippocampal kindling. Brain Research, 569, 341-347.
8. Hatton, J. D., & Ellisman, M. H. (1982). A restructuring of hypothalamic synapses is associated with motherhood. Journal of Neuroscience, 2, 704-707.
9. Hornykiewicz, O., & Kish, S. J. (1986). Biochemical pathophysiology of Parkinson's disease. Advances in Nenrology, 45, 19-34.
10. Itarat, W., & Jones, D. G. (1992). Perforated synapses are present during synaptogenesis in rat neocortex. Synapse, 11, 279-286.
11. Jedrzejewska, A., Wierzba-Bobrowicz, T., Olejniczak, P., Poszwinska, Z., & Dymecky, J. (1990). Ultrastructure and immunocytochemistry of left and right nigrostriatal system after lesion of right side of substantia nigra of rat. Advances in Neurology, 53, 41-49.
12. Kitai, S. T., Kocsis, J. D., & Wood, J. (1976). Origin and characteristics of the corticocaudate afferents: An anatomical and electrophysiological study. Brain Research, 118, 137-141.
13. Nieto-Sampedro, M., Hoff, S. F., & Cotman, C. W. (1982). Perforated postsynaptic densities: Probable intermediates in synapse turnover. Proceedings of the National Academy of Sciences, 79, 5718-5722.
14. Paxinos, G., & Watson, C. (1986). The rat brain in Stereotaxic Coordinates (2nd ed.). New York: Academic Press.
15. Petit, T. L. (1988). Synaptic plasticity and the structural basis of learning and memory. In T. L. Petit, & G. O. Ivy (Eds.), Neurology and neurobiology. Neural plasticity: A life time approach (vol 36, pp. 201-234). New York: Liss.
16. See, R. E., Chapman, M. A., & Menshul, C. K. (1992). Comparison of chronic intermittent haloperidol and raclopride effects on striatal dopamine release and synaptic ultrastructure in rats. Synapse, 12, 147-154.
17. Sirevaag, A. M., & Greenough, W. T. (1985). Differential rearing effects on rat visual cortax synapses. II. Synaptic morphometry. Developmenlal Brain Research, 19, 215-226.
18. Ungerstedt, U. (1968). 6-Hydroxydopamine induced degeneration of central monoaminergic neurons. European Journal of Pharmacology, 5, 107-110.
19. Ungerstedt, U. (1971). Postsynaptic supersensilivity after 6-OHDA induced degeneration of the nigro-striatal dopamine system. Acta Physiologica Scandinavia (Suppl.), 367, 69-93.
20. Vrensen, G., & Nunez, J. (1981). Changes in size and shape of synaptic connections after visual training: An ultrastructural approach of synaptic plasticity. Brain Research, 218, 79-97.