Efficacy of screening the intermediate cluster region of the bcl2 gene in follicular lymphomas by PCR

Journal of Clinical Pathology

Volumn 58, Issue 1, 2005, Pages 81-82

  Batstone, P J ^a   Goodlad, J R ^a  

^a RAIGMORE HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN BCL 2;

ARTICLE; B CELL LYMPHOMA; CHROMOSOME REARRANGEMENT; CONTROLLED STUDY; FOLLICULAR LYMPHOMA; GENE CLUSTER; GENE OVEREXPRESSION; HUMAN; HUMAN TISSUE; ONCOGENE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL;

CHROMOSOMES, HUMAN, PAIR 14; CHROMOSOMES, HUMAN, PAIR 18; GENE REARRANGEMENT; GENES, BCL-2; GENETIC SCREENING; HUMANS; LYMPHOMA, B-CELL; LYMPHOMA, FOLLICULAR; POLYMERASE CHAIN REACTION; TRANSLOCATION, GENETIC;

EID: 11244253754     PISSN: 00219746     EISSN: None     Source Type: Journal    
DOI: 10.1136/jcp.2004.018135     Document Type: Article

References (6)

1. Cleary ML, Sklar J. Nucleotide sequence of a t(14;18) chromosomal breakpoint in follicular lymphoma and demonstration of a breakpoint cluster region near a transcriptionally active locus on chromosome 18. Proc Natl Acad Sci U S A 1985;82:7439-43.
2. Cleary ML, Galili N, Sklar J. Detection of a second t(14;18) breakpoint cluster region in human follicular lymphomas. J Exp Med 1986;164:315-20.
3. Akasaka T, Akasaka H, Yonetani N, et al. Refinement of the BCL2/immunoglobulin heavy chain fusion gene in t(14;18)(q32;q21) by polymerase chain reaction amplification for long targets. Genes Chromosomes Cancer 1998;21:17-29.
4. Willis TG, Jadayel DM, Coignet LJ, et al. Rapid molecular cloning of rearrangements of IGHJ locus using long distance inverse polymerase chain reaction. Blood 1997;90:2456-64.
5. Albinger-Hegyi A, Hochreutener B, Abdou M-T, et al. High frequency of t(14;18]-translocation breakpoints outside of major breakpoint and minor cluster regions in follicular lymphoma. Am J Pathol 2002;160:823-32.
6. van-Dongen JJM, Langerak AW, Bruggermann M, et al. Design and standardization of PCR primers and protocols for detection of clonal immunoglobulin and T-cell receptor gene recombinations in suspect lymphoproliferations: Report of the BIOMED-2 Concerted Action BMH4-CT98-3936. Leukemia 2003;17:2257-317.