Lack of association between the interleukin-1 alpha (-889) polymorphism and early-onset Parkinson's disease

Neuroscience Letters

Volumn 359, Issue 3, 2004, Pages 195-197

  Möller, Jens Carsten ^a   Depboylu, Candan ^b   Kölsch, Heike ^b   Lohmüller, Frank ^a   Bandmann, Oliver ^a   Gocke, Petra ^a   Du, Yansheng ^c   Paus, Sebastian ^b   Wüllner, Ullrich ^b   Gasser, Thomas ^d   Oertel, Wolfgang H ^a   Klockgether, Thomas ^b   Dodel, Richard C ^b  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

^b UNIVERSITY OF BONN   (Germany)

^c INDIANA UNIVERSITY   (United States)

^d UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

Genes; Inflammation; Interleukins; Parkinson's disease

Indexed keywords

INTERLEUKIN 1ALPHA;

ADULT; ALLELE; ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; DNA POLYMORPHISM; FEMALE; GENETIC ASSOCIATION; GENETIC RISK; HUMAN; MAJOR CLINICAL STUDY; MALE; ONSET AGE; PARKINSON DISEASE; PRIORITY JOURNAL; PROMOTER REGION;

ADULT; CASE-CONTROL STUDIES; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENETIC SCREENING; GERMANY; HUMANS; INTERLEUKIN-1; MALE; MIDDLE AGED; PARKINSON DISEASE; POLYMORPHISM, GENETIC; RISK ASSESSMENT; STATISTICS;

EID: 11144358419     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2004.01.058     Document Type: Article

References (12)

1. Bonifati V., Rizzu P., Van Baren M.J., Schaap O., Breedveld G.J., Krieger E., Dekker M.C., Squitieri F., Ibanez P., Joosse M., Van Dongen J.W., Vanacore N., Van Swieten J.C., Brice A., Meco G., Van Duijn C.M., Oostra B.A., Heutink P. Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism. Science. 299:2003;256-259.
2. Dodel R.C., Lohmuller F., Du Y., Eastwood B., Gocke P., Oertel W.H., Gasser T. A polymorphism in the intronic region of the IL-1alpha gene and the risk for Parkinson's disease. Neurology. 56:2001;982-983.
3. Du Y., Dodel R.C., Eastwood B.J., Bales K.R., Gao F., Lohmuller F., Muller U., Kurz A., Zimmer R., Evans R.M., Hake A., Gasser T., Oertel W.H., Griffin W.S., Paul S.M., Farlow M.R. Association of an interleukin 1 alpha polymorphism with Alzheimer's disease. Neurology. 55:2000;480-483.
4. Gibb W.R., Lee A.J. The relevance of the Lewy body to the pathogenesis of idiopathic Parkinson's disease. J. Neurol. Neursurg Psychiatry. 51:1988;745-752.
5. Kruger R., Kuhn W., Muller T., Woitalla D., Graeber M., Kosel S., Przuntek H., Epplen J.T., Schols L., Riess O. Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease. Nat. Genet. 18:1998;106-108.
6. Mattila K.M., Rinne J.O., Lehtimaki T., Roytta M., Ahonen J.P., Hurmey M. Association of an interleukin 1B gene polymorphism (-511) with Parkinson's disease in Finnish patients. J. Med. Genet. 39:2002;400-402.
7. McGeer P.L., Yasojima K., McGeer E.G. Association of interleukin-1 beta polymorphisms with idiopathic Parkinson's disease. Neurosci. Lett. 326:2002;67-69.
8. Nishimura M., Mizuta I., Mizuta E., Yamasaki S., Ohta M., Kuno S. Influence of interleukin-1beta gene polymorphisms on age-at-onset of sporadic Parkinson's disease. Neurosci. Lett. 284:2000;73-76.
9. Polymeropoulos M.H., Lavedan C., Leroy E., Die S.E., Dehejia A., Dutra A., Pike B., Root H., Rubenstein J., Boyer R., Stenroos E.S., Chandrasekharappa S., Athanassiadou A., Papapetropoulos T., Johnson W.G., Lazzarini A.M., Duvoisin R.C., Di Iorio G., Golbe L.I., Nussbaum R.L. Mutation in the synuclein gene identified in families with Parkinson's disease. Science. 276:1997;2045-2047.
10. Schulte T., Schols L., Müller T., Woitalla D., Berger K., Krüger R. Polymorphisms in the interleukin-1 alpha and beta genes and the risk for Parkinson's disease. Neurosci. Lett. 326:2002;70-72.
11. Wüllner U., Klockgether T. Inflammation in Parkinson's disease. J. Neurol. 250:(Suppl. 1):2003;I35-I38.
12. Zimprich A., Muller-Myhsok B., Farrer M., Leitner P., Sharma M., Hulihan M., Lockhart P., Strongosky A., Kachergus J., Calne D.B., Stoessl J., Uitti R.J., Pfeiffer R.F., Trenkwalder C., Homann N., Ott E., Wenzel K., Asmus F., Hardy J., Wszolek Z., Gasser T. The PARK8 locus in autosomal dominant Parkinsonism: confirmation of linkage and further delineation of the disease-containing interval. Am. J. Hum. Genet. 74:2004;11-19.