Development of a scalable process for CI-1034, an endothelin antagonist

Organic Process Research and Development

Volumn 8, Issue 2, 2004, Pages 201-212

  Jacks, Thomas E ^a,c   Belmont, Daniel T ^a,b   Briggs, Christopher A ^a   Horne, Nicole M ^a   Kanter, Gerald D ^b   Karrick, Greg L ^a   Krikke, James J ^a,f   McCabe, Richard J ^a   Mustakis, Jason G ^a   Nanninga, Thomas N ^a   Risedorph, Guy S ^a,d   Seamans, Ronald E ^a   Skeean, Richard ^b   Winkle, Derick D ^a,e   Zennie, Thomas M ^a,d  

^a PFIZER INC   (United States)

^b Ann Arbor VA HSR and D   (United States)

^c J Star Research Inc   (United States)

^d ELI LILLY AND COMPANY   (United States)

^e Pleotint LLC   (United States)

^f GRAND VALLEY STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 VANILLIN; BENZENE DERIVATIVE; BENZENESULFONYL CHLORIDE; BENZOTHIAZINE DERIVATIVE; BORONIC ACID DERIVATIVE; CI 1034; ENDOTHELIN RECEPTOR ANTAGONIST; ESTER DERIVATIVE; MAGNESIUM CHLORIDE; SULFONIC ACID DERIVATIVE; TITANIUM DERIVATIVE; TRIFLUOROMETHANESULFONIC ACID; UNCLASSIFIED DRUG; VANILLIN DERIVATIVE;

ARTICLE; CHROMATOGRAPHY; DIECKMANN REACTION; DRUG STRUCTURE; DRUG SYNTHESIS; QUANTITATIVE ANALYSIS; REACTION ANALYSIS; STRUCTURE ANALYSIS; SUZUKI REACTION; TECHNIQUE;

EID: 11144357278     PISSN: 10836160     EISSN: None     Source Type: Journal    
DOI: 10.1021/op034104g     Document Type: Article

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