Effects of perindopril-based blood pressure lowering and of patient characteristics on the progression of silent brain infarct: The perindopril protection against recurrent stroke study (PROGRESS) CT substudy in Japan

Hypertension Research

Volumn 27, Issue 3, 2004, Pages 147-156

  Hasegawa, Yasuhiro ^a   Yamaguchi, Takenori ^a   Omae, Teruo ^a   Woodward, Mark ^a   Chalmers, John ^a   Takasaki, M ^b   Iwamoto, T ^b   Tohgi, H ^c   Takahashi, H ^c   Konno, S ^c   Uchiyama, S ^d   Kimura, Y ^d   Hayakawa, I ^e   Miyamori, T ^e   Ishitsuka, T ^f   Shiokawa, O ^f   Nakano, M ^g   Takenoyama, T ^g   Fukiyama, K ^h   Muratani, H ^h   Hirose, G ⁱ   Kataoka, S ⁱ   Sakai, F ^j   Kanda, T ^j   Kitagawa, Y ^k   Yoshitoshi, M ^k   Shinohara, Y ^l   Takizawa, S ^l   Kazabari, S ^l   Mihara, B ^m   Kawagishi, Y ^m   Makishita, H ⁿ   Isomura, K ⁿ   Tabata, K ^o   Nakagawa, S ^o   Okada, H ^p   Takeda, A ^p   Nakajima, K ^q   Makino, M ^q   Hirata, Y ^r   Watahiki, Y ^r   Kawamura, J ^s   Yoshikawa, N ^s   Takastuka, K ^s   Akiguchi, I ^t   Wakita, H ^t   Tomimoto, H ^t   Nakamura, S ^u   Kohriyama, T ^u   Hiwada, K ^v   Shigematsu, Y ^v   Yanagihara, T ^w   Matsumoto, M ^w   Ueda, H ^w   Nishimaru, K ^x   Setsu, K ^x   Kobayashi, S ^y   Yamaguchi, S ^y   Hashimoto, S ^z   Nakamura, M ^z   Mitake, S ^aa   Uchida, M ^aa   Ishihara, N ^ab   Imai, N ^ac   Imaizumi, M ^ad   Hokezu, Y ^ae   Satake, M ^ae   more..

^a NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

^b TOKYO MEDICAL UNIVERSITY HOSPITAL   (Japan)

^c IWATE MEDICAL UNIVERSITY   (Japan)

^d TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

^e KAWASAKI MUNICIPAL HOSPITAL   (Japan)

^f KYUSHU ROSAI HOSPITAL   (Japan)

^g National Hospital Organization   (Japan)

^h UNIVERSITY OF THE RYUKYUS   (Japan)

ⁱ KANAZAWA MEDICAL UNIVERSITY   (Japan)

^j KITASATO UNIVERSITY   (Japan)

^k TOKAI UNIVERSITY OISO HOSPITAL   (Japan)

^l TOKAI UNIVERSITY   (Japan)

^m Mihara Memorial Hospital   (Japan)

ⁿ Hokushin General Hospital   (Japan)

^o Nagano Prefectural Federation of Agricultural Cooperative for Health and Welfare   (Japan)

^p SHIZUOKA MEDICAL CENTER   (Japan)

^q KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

^r RESEARCH INSTITUTE FOR BRAIN AND BLOOD VESSELS AKITA   (Japan)

^s KOBE CITY MEDICAL CENTER GENERAL HOSPITAL   (Japan)

^t KYOTO UNIVERSITY HOSPITAL   (Japan)

^u HIROSHIMA UNIVERSITY   (Japan)

^v EHIME UNIVERSITY HOSPITAL   (Japan)

^w OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

^x FUKUOKA UNIVERSITY   (Japan)

^y SHIMANE UNIVERSITY   (Japan)

^z TENRI HOSPITAL   (Japan)

^aa TOSEI GENERAL HOSPITAL   (Japan)

^ab KEIO UNIVERSITY   (Japan)

^ac Shimizu Municipal Hospital   (Japan)

^ad OSAKA NATIONAL HOSPITAL   (Japan)

^ae OITA PREFECTURAL HOSPITAL   (Japan)

more..

Author keywords

Cerebrovascular disease; Hypertension; Peridopril; Recurrent stroke; Stroke subtype

Indexed keywords

ACETYLSALICYLIC ACID; ANTICOAGULANT AGENT; CALCIUM CHANNEL BLOCKING AGENT; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DIURETIC AGENT; INDAPAMIDE; PERINDOPRIL; PLACEBO;

ADULT; ANTIHYPERTENSIVE ACTIVITY; ARTICLE; BRAIN ATROPHY; BRAIN INFARCTION; BRAIN SCINTISCANNING; CEREBROVASCULAR ACCIDENT; CLINICAL TRIAL; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; DISEASE COURSE; DOSE RESPONSE; DRUG EFFICACY; FEMALE; FOLLOW UP; HUMAN; HYPERTENSION; JAPAN; MAJOR CLINICAL STUDY; MALE; RANDOMIZED CONTROLLED TRIAL; RECURRENT DISEASE; RISK ASSESSMENT; STATISTICAL SIGNIFICANCE; STROKE; SYMPTOMATOLOGY; SYSTOLIC BLOOD PRESSURE;

AGED; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; ANTIHYPERTENSIVE AGENTS; BLOOD PRESSURE; BRAIN; CEREBRAL INFARCTION; CEREBROVASCULAR ACCIDENT; DIASTOLE; DISEASE PROGRESSION; DIURETICS; DOUBLE-BLIND METHOD; DRUG THERAPY, COMBINATION; FEMALE; FOLLOW-UP STUDIES; HUMANS; INDAPAMIDE; JAPAN; MALE; MIDDLE AGED; PERINDOPRIL; RECURRENCE; TOMOGRAPHY, X-RAY COMPUTED; TREATMENT OUTCOME;

EID: 11144354201     PISSN: 09169636     EISSN: None     Source Type: Journal    
DOI: 10.1291/hypres.27.147     Document Type: Article

References (45)

1. Longstreth WT Jr, Bernick C, Manolio TA, Byan N, Jungreis CA, Price TR, for the Cardiovascular Health Study Collaborative Research Group: Lacunnar infarcts defined by magnetic resonance imaging of 3660 elderly people. Arch Neurol 1998; 55: 1217-1225.
2. Bernick C, Kuller L, Dulberg C, et al, for the Cardiovascular Health Study Collaborative Research Group: Silent MRI infarcts and the risk of future stroke: the Cardiovascular Health Study. Neurology 2001; 57:1222-1229.
3. Vermeer SE, Prins ND, den Heijer T, Hofman A, Koudstaal PJ, Breteler MM: Silent brain infarcts and the risk of dementia and cognitive decline. N Engl J Med 2003; 348: 1215-1222.
4. Shintani S, Shiigai T, Arinami T: Subclinical cerebral lesion accumulation on serial magnetic resonance imaging (MRI) in patients with hypertension: risk factors. Acta Neurol Scand 1998; 97: 251-269.
5. Sugiyama T, Lee JD, Shimizu H, Abe S, Ueda T: Influence of treated blood pressure on progression of silent cerebral infarction. J Hypertens 1999; 17: 679-684.
6. Ezekowitz MD, James KE, Nazarian SM, et al, for the Veterans Affairs Stroke Prevention in Nonrheumatic Atrial Fibrillation Investigators: silent cerebral infarction in patients with nonrheumatic atrial fibrillation. Circulation 1995; 92: 2178-2182.
7. Prospective Studies Collaboration: Cholesterol, diastolic blood pressure, and stroke: 13,000 strokes in 450,000 people in 45 prospective cohorts. Lancet 1995; 346; 1647-1653.
8. Omae T, Ueda K: Hypertension and cerebrovascular disease - the Japanese experience. J Hypertens 1988; 6: 343-349.
9. Asia Pacific Cohort Studies Collaboration: Blood pressure and cardiovascular diseases in the Asia-Pacific region. J Hypertens 2003; 21: 707-716.
10. MacMahon S, Peto R, Cutler J, et al: Blood pressure, stroke, and coronary heart disease: part 1: prolonged differences in blood pressure: prospective observational studies correlated for the regression dilution bias. Lancet 1990; 335: 756-774.
11. UK-TIA Study Group: The United Kingdom transient ischemic attack (UK-TIA) aspirin trial: final results. J Neurol Neurosurg Psychiatry 1991; 54: 1044-1054.
12. Scheinberg P: Dementia due to vascular disease: a multifactorial disorder. Stroke 1988; 19: 1291-1299.
13. Tzourio C, Dufouil C, Ducimetiere P, Alperovitch A: Cognitive decline in individuals with high blood pressure: a longitudinal study in the elderly: EVA Study Group: Epidemiology of Vascular Aging. Neurology 1999; 53: 1948-1952.
14. Qiu C, von Strauss E, Fastbom J, Winblad B, Fratiglioni L: Low blood pressure and risk of dementia in the Kungsholmen project: a 6-year follow-up study. Arch Neurol 2003; 60: 223-228.
15. Watanabe N, Imai Y, Nagai K, et al: Nocturnal blood pressure and silent cerebrovascular lesions in elderly Japanese. Stroke 1996; 27: 1319-1327.
16. Kario K, Matsuo T, Kobayashi H, Imiya M, Matsuo M, Shimada K: Nocturnal fall of blood pressure and silent cerebrovascular damage in elderly hypertensive patients: advanced silent cerebrovascular damage in extreme dippers. Hypertension 1996: 27:130-135.
17. Bosch J, Yusuf S, Progue J, et al, on behalf of HOPE: Use of ramipril in preventing stroke: double blind randomized trial. BMJ 2002; 324: 699-702.
18. The Heart Outcome Prevention Evaluation Study Investigators: Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high risk patients. N Engl J Med 2000; 342: 145-153.
19. Gorelick PB: Stroke prevention therapy beyond antithrombotics: unifying mechanisms in ischemic stroke pathogenesis and implications for therapy. Stroke 2002; 33: 862-875.
20. Dahlöf B, Devereux RB, Kjeldsen SE, et al, the LIFE Study Group: Cardiovascular morbidity and mortality in the Losartan Intervention For Endpoint reduction in hypertension study (LIFE): a randomized trial against atenorol. Lancet 2002; 359: 995-1003.
21. Fennessy PA, Campbell JH, Campbell GR: An angiotensin converting enzyme inhibitor, perindopril, prevents progression of preformed atherosclerotic lesion in the cholesterol-fed rabbits. Clin Sci 1994; 87: 685-691.
22. Candido R, Jandeleit-Dahm KA, Cao Z, et al: Prevention of accelerated atherosclerosis by angiotensin-converting enzyme inhibition in diabetic apolipoprotein E-deficient mice. Circulation 2002; 106: 246-253.
23. PROGRESS Collaborative Group: Randomized trial of a perindopril-based blood-pressure-lowering regimen among 6105 individuals with previous stroke or transient ischemic attack. Lancet 2001; 358: 1033-1041.
24. PROGRESS Collaborative Group: Effects of a perindopril-based blood-pressure-lowering regimen on cardiac outcomes among patients with cerebrovascular disease. Eur Heart J 2003; 24: 475-484.
25. The PROGRESS Collaborative Group: Effects of blood pressure lowering with perindopril and indapamide therapy on dementia and cognitive decline in patients with cerebrovascular disease. Arch Intern Med 2003; 163: 1069-1075.
26. PROGRESS Management Committee: Blood pressure lowering for the secondary prevention of stroke: rationale and design for PROGRESS. J Hypertens 1996; 14 (Suppl 2): S41-S46.
27. PROGRESS Management Committee: PROGRESS - Perindopil Protection against Recurrent Stroke Study: characteristics of the study population at baseline. J Hypertens 1999; 17: 1647-1655.
28. Folstein MF, Folstein SE, McHuh PR: "Mini-mental state": practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 1975; 12: 189-198.
29. Mahoney FI, Barthel DW: Functional evaluation: the Barthel Index. Md State Med J 1965; 14: 61-65.
30. Lindley RI, Waddell F, Livingstone M, et al: Can simple questions assess outcome after stroke? Cerebrovasc Dis 1994; 4: 314-324.
31. Soininen H, Puranen M, Riekkinen PJ: Computed tomography findings in senile dementia and normal aging. J Neurol Neurosurg Psychiatry 1982; 45: 50-54.
32. Chalmers J, Neal B, MacMahon S, on behalf of the PROGRESS Management Committee: PROGRESS (Perindopril Protection against Recurrent Stroke Study): regional characteristics of the study population at baseline. J Hypertens 2000; 18 (Suppl 1): S13-S19.
33. Lechner H, Schmidt R, Bertha G, Justich E, Offenbacher H, Schneider G: Nuclear magnetic resonance image white matter lesions and risk factors for stroke in normal individuals. Stroke 1988; 19: 263-265.
34. Skoog I, Lernfelt B, Landahl S, et al: 15-year longitudinal study of blood pressure and dementia. Lancet 1996; 347: 1141-1145.
35. Dyker AG, Grosset DG, Lees K: Perindopril reduces blood pressure but not cerebral blood flow in patients with recent cerebral ischemic stroke. Stroke 1997; 28: 580-583.
36. Walters MR, Bolster A, Dyker AG, Lees KR: Effect of perindopril on cerebral and renal perfusion in stroke patients with carotid disease. Stroke 2001; 32: 473-478.
37. Lonn E, Yusuf S, Dzavik V, et al, SECURE Investigators: Effects of ramipril and vitamin E on atherosclerosis: the study to evaluate carotid ultrasound changes in patients treated with ramipil and vitamin E (SECURE). Circulation 2001; 103: 919-925.
38. MacMahon S, Sharpe N, Gamble G, et al: Randomized, placebo-controlled trial of the angiotensin-converting enzyme inhibitor, ramipril, in patients with coronary or other occlusive arterial disease: part-2: Collaborative Research Group: prevention of atherosclerosis with ramipril. J Am Coll Cardiol 2000; 36: 438-443.
39. Kivipelto M, Helkala E-L, Laakso MP, et al: Midlife vascular risk factors and Alzheimer's disease in late life: longitudinal, population based study. BMJ 2001; 322: 1447-1451.
40. Launer LJ, Ross GW, Petrovitch H, et al: Midlife blood pressure and dementia: the Honolulu-Asia Aging Study. Neurobiol Aging 2000; 21: 49-55.
41. Reinprecht F, Elmstahl S, Janzon L, et al: Hypertension and changes of cognitive function in 81-year-old men: a 13-year follow-up of the population study 'Men born in 1914,' Sweden. J Hypertens 2003; 21: 57-66.
42. Sparks DL, Scheff SW, Liu H, et al: Increased incidence of neurofibrillary tangles (NFT) in non-demented individuals with hypertension. J Neurol Sci 1995; 131: 162-169.
43. Petrovitch H, White LR, Izmirilian G, et al: Midlife blood pressure and neuritic plaques, neuro-fibrillary tangles, and brain weight at death: the HAAS. Neurobiol Aging 2000; 21: 57-62.
44. Snowdon D, Greiner L, Mortimer J, et al: Brain infarction and the clinical expression of Alzheimer's disease: the Nun Study. JAMA 1997; 227: 813-817.
45. Evans D, Funkenstein H, Albert M, et al: Prevalence of Alzheimer's disease in a community population of older persons: higher than previously reported. JAMA 1989; 262: 2551-2556.