메뉴 건너뛰기




Volumn 10, Issue 12, 2004, Pages 1307-1320

An innately interesting decade of research in immunology

Author keywords

[No Author keywords available]

Indexed keywords

CYTIDINE DEAMINASE; NATURAL KILLER CELL RECEPTOR NKG2D; TOLL LIKE RECEPTOR; TUMOR NECROSIS FACTOR;

EID: 11144340471     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/nm1159     Document Type: Review
Times cited : (123)

References (298)
  • 3
    • 2442700490 scopus 로고
    • Partial Cell Functions (lecture, 1908)
    • Elsevier Publishing Company, Amsterdam
    • Ehrlich, P. Partial Cell Functions (lecture, 1908). in Nobel Lectures, Physiology or Medicine 1901-1921. (Elsevier Publishing Company, Amsterdam, 1967).
    • (1967) Nobel Lectures, Physiology or Medicine 1901-1921
    • Ehrlich, P.1
  • 4
    • 0014513216 scopus 로고
    • The covalent structure of an entire γG immunoglobulin molecule
    • Edelman, G.M. et al. The covalent structure of an entire γG immunoglobulin molecule. Proc. Natl. Acad. Sci. USA 63, 78-85 (1969).
    • (1969) Proc. Natl. Acad. Sci. USA , vol.63 , pp. 78-85
    • Edelman, G.M.1
  • 5
  • 6
    • 0018654090 scopus 로고
    • Three-dimensional structure of immunoglobulins
    • Amzel, L.M. & Poljak, R.J. Three-dimensional structure of immunoglobulins. Annu. Rev. Biochem. 48, 961-997 (1979).
    • (1979) Annu. Rev. Biochem. , vol.48 , pp. 961-997
    • Amzel, L.M.1    Poljak, R.J.2
  • 7
    • 0023176346 scopus 로고
    • Structure of the human class I histocompatibility antigen, HLA-A2
    • Bjorkman, P.J. et al. Structure of the human class I histocompatibility antigen, HLA-A2. Nature 329, 506-512 (1987).
    • (1987) Nature , vol.329 , pp. 506-512
    • Bjorkman, P.J.1
  • 8
    • 0018093829 scopus 로고
    • A complete immunoglobulin gene is created by somatic recombination
    • Brack, C., Hirama, M., Lenhard-Schuller, R. & Tonegawa, S. A complete immunoglobulin gene is created by somatic recombination. Cell 15, 1-14 (1978).
    • (1978) Cell , vol.15 , pp. 1-14
    • Brack, C.1    Hirama, M.2    Lenhard-Schuller, R.3    Tonegawa, S.4
  • 9
    • 0021215865 scopus 로고
    • Isolation of cDNA clones encoding T cell-specific membrane-associated proteins
    • Hedrick, S.M., Cohen, D.I., Nielsen, E.A. & Davis, M.M. Isolation of cDNA clones encoding T cell-specific membrane-associated proteins. Nature 308, 149-153 (1984).
    • (1984) Nature , vol.308 , pp. 149-153
    • Hedrick, S.M.1    Cohen, D.I.2    Nielsen, E.A.3    Davis, M.M.4
  • 10
    • 0021196170 scopus 로고
    • A human T cell-specific cDNA clone encodes a protein having extensive homology to immunoglobulin chains
    • Yanagi, Y. et al. A human T cell-specific cDNA clone encodes a protein having extensive homology to immunoglobulin chains. Nature 308, 145-149 (1984).
    • (1984) Nature , vol.308 , pp. 145-149
    • Yanagi, Y.1
  • 11
    • 0015518021 scopus 로고
    • Histocompatibility-linked immune response genes
    • Benacerraf, B. & McDevitt, H.O. Histocompatibility-linked immune response genes. Science 175, 273-279 (1972).
    • (1972) Science , vol.175 , pp. 273-279
    • Benacerraf, B.1    McDevitt, H.O.2
  • 12
    • 0015898251 scopus 로고
    • Function of macrophages in antigen recognition by guinea pig T lymphocytes. I. Requirement for histocompatible macrophages and lymphocytes
    • Rosenthal, A.S. & Shevach, E.M. Function of macrophages in antigen recognition by guinea pig T lymphocytes. I. Requirement for histocompatible macrophages and lymphocytes. J. Exp. Med. 138, 1194-1212 (1973).
    • (1973) J. Exp. Med. , vol.138 , pp. 1194-1212
    • Rosenthal, A.S.1    Shevach, E.M.2
  • 13
    • 0016345568 scopus 로고
    • Restriction of in vitro T cell-mediated cytotoxicity in lymphocytic choriomeningitis within a syngeneic or semiallogeneic system
    • Zinkernagel, R.M. & Doherty, P.C. Restriction of in vitro T cell-mediated cytotoxicity in lymphocytic choriomeningitis within a syngeneic or semiallogeneic system. Nature 248, 701-702 (1974).
    • (1974) Nature , vol.248 , pp. 701-702
    • Zinkernagel, R.M.1    Doherty, P.C.2
  • 14
    • 0022129512 scopus 로고
    • Cytotoxic T cells recognize fragments of the influenza nucleoprotein
    • Townsend, A.R., Gotch, F.M. & Davey, J. Cytotoxic T cells recognize fragments of the influenza nucleoprotein. Cell 42, 457-467 (1985).
    • (1985) Cell , vol.42 , pp. 457-467
    • Townsend, A.R.1    Gotch, F.M.2    Davey, J.3
  • 15
    • 0021968677 scopus 로고
    • Binding of immunogenic peptides to Ia histocompatibility molecules
    • Babbitt, B.P., Allen, P.M., Matsueda, G., Haber, E. & Unanue, E.R. Binding of immunogenic peptides to Ia histocompatibility molecules. Nature 317, 359-361 (1985).
    • (1985) Nature , vol.317 , pp. 359-361
    • Babbitt, B.P.1    Allen, P.M.2    Matsueda, G.3    Haber, E.4    Unanue, E.R.5
  • 16
    • 0021051781 scopus 로고
    • The Ia molecule of the antigen-presenting cell plays a critical role in immune response gene regulation of T cell activation
    • Heber-Katz, E., Hansburg, D. & Schwartz, R.H. The Ia molecule of the antigen-presenting cell plays a critical role in immune response gene regulation of T cell activation. J. Mol. Cell. Immunol. 1, 3-18 (1983).
    • (1983) J. Mol. Cell. Immunol. , vol.1 , pp. 3-18
    • Heber-Katz, E.1    Hansburg, D.2    Schwartz, R.H.3
  • 17
    • 0023115557 scopus 로고
    • The relation between major histocompatibility complex (MHC) restriction and the capacity of Ia to bind immunogenic peptides
    • Buus, S., Sette, A., Colon, S.M., Miles, C. & Grey, H.M. The relation between major histocompatibility complex (MHC) restriction and the capacity of Ia to bind immunogenic peptides. Science 235, 1353-1358 (1987).
    • (1987) Science , vol.235 , pp. 1353-1358
    • Buus, S.1    Sette, A.2    Colon, S.M.3    Miles, C.4    Grey, H.M.5
  • 18
    • 0028773294 scopus 로고
    • Antigenic peptide binding by class I and class II histocompatibility proteins
    • Stern, L.J. & Wiley, D.C. Antigenic peptide binding by class I and class II histocompatibility proteins. Structure 2, 245-251 (1994).
    • (1994) Structure , vol.2 , pp. 245-251
    • Stern, L.J.1    Wiley, D.C.2
  • 19
    • 0028038426 scopus 로고
    • MHC-dependent antigen processing and peptide presentation: Providing ligands for T lymphocyte activation
    • Germain, R.N. MHC-dependent antigen processing and peptide presentation: providing ligands for T lymphocyte activation. Cell 76, 287-299 (1994).
    • (1994) Cell , vol.76 , pp. 287-299
    • Germain, R.N.1
  • 20
    • 0034969086 scopus 로고    scopus 로고
    • Factors and forces controlling V(D)J recombination
    • Hesslein, D.G. & Schatz, D.G. Factors and forces controlling V(D)J recombination. Adv. Immunol. 78, 169-232 (2001).
    • (2001) Adv. Immunol. , vol.78 , pp. 169-232
    • Hesslein, D.G.1    Schatz, D.G.2
  • 21
    • 0842303307 scopus 로고    scopus 로고
    • Unraveling V(D)J recombination; insights into gene regulation
    • Jung, D. & Alt, F.W. Unraveling V(D)J recombination; insights into gene regulation. Cell 116, 299-311 (2004).
    • (2004) Cell , vol.116 , pp. 299-311
    • Jung, D.1    Alt, F.W.2
  • 22
    • 2942613670 scopus 로고    scopus 로고
    • AID: How does it aid antibody diversity?
    • Honjo, T., Muramatsu, M. & Fagarasan, S. AID: how does it aid antibody diversity? Immunity 20, 659-668 (2004).
    • (2004) Immunity , vol.20 , pp. 659-668
    • Honjo, T.1    Muramatsu, M.2    Fagarasan, S.3
  • 23
    • 0036226836 scopus 로고    scopus 로고
    • MHC-dependent survival of naive T cells? A complicated answer to a simple question
    • Dorfman, J.R. & Germain, R.N. MHC-dependent survival of naive T cells? A complicated answer to a simple question. Microbes Infect. 4, 547-554 (2002).
    • (2002) Microbes Infect. , vol.4 , pp. 547-554
    • Dorfman, J.R.1    Germain, R.N.2
  • 24
    • 0036141994 scopus 로고    scopus 로고
    • Costimulation and endogenous MHC ligands contribute to T cell recognition
    • Wulfing, C. et al. Costimulation and endogenous MHC ligands contribute to T cell recognition. Nat. Immunol. 3, 42-47 (2002).
    • (2002) Nat. Immunol. , vol.3 , pp. 42-47
    • Wulfing, C.1
  • 25
    • 0037191792 scopus 로고    scopus 로고
    • Self-recognition promotes the foreign antigen sensitivity of naive T lymphocytes
    • Stefanova, I., Dorfman, J.R. & Germain, R.N. Self-recognition promotes the foreign antigen sensitivity of naive T lymphocytes. Nature 420, 429-434 (2002).
    • (2002) Nature , vol.420 , pp. 429-434
    • Stefanova, I.1    Dorfman, J.R.2    Germain, R.N.3
  • 26
    • 0032968708 scopus 로고    scopus 로고
    • The dynamics of T cell receptor signaling: Complex orchestration and the key roles of tempo and cooperation
    • Germain, R.N. & Stefanova, I. The dynamics of T cell receptor signaling: complex orchestration and the key roles of tempo and cooperation. Annu. Rev. Immunol. 17, 467-522 (1999).
    • (1999) Annu. Rev. Immunol. , vol.17 , pp. 467-522
    • Germain, R.N.1    Stefanova, I.2
  • 28
    • 0024955886 scopus 로고
    • Approaching the asymptote? Evolution and revolution in immunology
    • Janeway, C.A., Jr. Approaching the asymptote? Evolution and revolution in immunology. Cold Spring Harb. Symp. Quant. Biol. 1, 1-13 (1989).
    • (1989) Cold Spring Harb. Symp. Quant. Biol. , vol.1 , pp. 1-13
    • Janeway Jr., C.A.1
  • 29
    • 0028201732 scopus 로고
    • Tolerance, danger, and the extended family
    • Matzinger, P. Tolerance, danger, and the extended family. Annu. Rev. Immunol. 12, 991-1045 (1994).
    • (1994) Annu. Rev. Immunol. , vol.12 , pp. 991-1045
    • Matzinger, P.1
  • 30
    • 0030831210 scopus 로고    scopus 로고
    • A human homologue of the Drosophila Toll protein signals activation of adaptive immunity
    • Medzhitov, R., Preston-Hurlburt, P. & Janeway, C.A., Jr. A human homologue of the Drosophila Toll protein signals activation of adaptive immunity. Nature 388, 394-397 (1997).
    • (1997) Nature , vol.388 , pp. 394-397
    • Medzhitov, R.1    Preston-Hurlburt, P.2    Janeway Jr., C.A.3
  • 31
    • 0032509295 scopus 로고    scopus 로고
    • Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: Mutations in Tlr4 gene
    • Poltorak, A. et al. Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene. Science 282, 2085-2088 (1998).
    • (1998) Science , vol.282 , pp. 2085-2088
    • Poltorak, A.1
  • 32
    • 0242581687 scopus 로고    scopus 로고
    • The immune response of Drosophila
    • Hoffmann, J.A. The immune response of Drosophila. Nature 426, 33-38 (2003).
    • (2003) Nature , vol.426 , pp. 33-38
    • Hoffmann, J.A.1
  • 33
    • 0742272506 scopus 로고    scopus 로고
    • Sensing infection in Drosophila: Toll and beyond
    • Ferrandon, D., Imler, J.L. & Hoffmann, J.A. Sensing infection in Drosophila: Toll and beyond. Semin. Immunol. 16, 43-53 (2004).
    • (2004) Semin. Immunol. , vol.16 , pp. 43-53
    • Ferrandon, D.1    Imler, J.L.2    Hoffmann, J.A.3
  • 34
    • 0141799911 scopus 로고    scopus 로고
    • Defensins: Antimicrobial peptides of innate immunity
    • Ganz, T. Defensins: antimicrobial peptides of innate immunity. Nat. Rev. Immunol. 3, 710-720 (2003).
    • (2003) Nat. Rev. Immunol. , vol.3 , pp. 710-720
    • Ganz, T.1
  • 36
    • 4644330955 scopus 로고    scopus 로고
    • Toll-like receptor 9 binds single-stranded CpG-DNA in a sequence- And pH-dependent manner
    • Rutz, M. et al. Toll-like receptor 9 binds single-stranded CpG-DNA in a sequence- and pH-dependent manner. Eur. J. Immunol. 34, 2541-2550 (2004).
    • (2004) Eur. J. Immunol. , vol.34 , pp. 2541-2550
    • Rutz, M.1
  • 37
    • 0346731246 scopus 로고    scopus 로고
    • How we detect microbes and respond to them: The Toll-like receptors and their transducers
    • Beutler, B., Hoebe, K., Du, X. & Ulevitch, R.J. How we detect microbes and respond to them: the Toll-like receptors and their transducers. J. Leukoc. Biol. 74, 479-485 (2003).
    • (2003) J. Leukoc. Biol. , vol.74 , pp. 479-485
    • Beutler, B.1    Hoebe, K.2    Du, X.3    Ulevitch, R.J.4
  • 38
    • 0142031430 scopus 로고    scopus 로고
    • Role of Toll-like receptors in pathogen recognition
    • Janssens, S. & Beyaert, R. Role of Toll-like receptors in pathogen recognition. Clin. Microbiol. Rev. 16, 637-646 (2003).
    • (2003) Clin. Microbiol. Rev. , vol.16 , pp. 637-646
    • Janssens, S.1    Beyaert, R.2
  • 39
    • 0348135024 scopus 로고    scopus 로고
    • Dendritic-cell control of pathogen-driven T-cell polarization
    • Kapsenberg, M.L. Dendritic-cell control of pathogen-driven T-cell polarization. Nat. Rev. Immunol. 3, 984-993 (2003).
    • (2003) Nat. Rev. Immunol. , vol.3 , pp. 984-993
    • Kapsenberg, M.L.1
  • 40
    • 0742272509 scopus 로고    scopus 로고
    • Toll-like receptors and dendritic cells: For whom the bug tolls
    • Reis e Sousa, C. Toll-like receptors and dendritic cells: for whom the bug tolls. Semin. Immunol. 16, 27-34 (2004).
    • (2004) Semin. Immunol. , vol.16 , pp. 27-34
    • Reis E Sousa, C.1
  • 41
    • 5444262511 scopus 로고    scopus 로고
    • Toll-like receptor control of the adaptive immune responses
    • Iwasaki, A. & Medzhitov, R. Toll-like receptor control of the adaptive immune responses. Nat. Immunol. 5, 987-995 (2004).
    • (2004) Nat. Immunol. , vol.5 , pp. 987-995
    • Iwasaki, A.1    Medzhitov, R.2
  • 42
    • 0041931079 scopus 로고    scopus 로고
    • Not "molecular patterns" but molecules
    • Beutler, B. Not "molecular patterns" but molecules. Immunity 19, 155-156 (2003).
    • (2003) Immunity , vol.19 , pp. 155-156
    • Beutler, B.1
  • 44
    • 0038242875 scopus 로고    scopus 로고
    • Toll-like receptor signaling pathways
    • Barton, G.M. & Medzhitov, R. Toll-like receptor signaling pathways. Science 300, 1524-1525 (2003).
    • (2003) Science , vol.300 , pp. 1524-1525
    • Barton, G.M.1    Medzhitov, R.2
  • 45
    • 3142654210 scopus 로고    scopus 로고
    • Inferences, questions and possibilities in Toll-like receptor signalling
    • Beutler, B. Inferences, questions and possibilities in Toll-like receptor signalling. Nature 430, 257-263 (2004).
    • (2004) Nature , vol.430 , pp. 257-263
    • Beutler, B.1
  • 46
    • 2142762520 scopus 로고    scopus 로고
    • TLRs: Differential adapter utilization by toll-like receptors mediates TLR-specific patterns of gene expression
    • Vogel, S.N., Fitzgerald, K.A. & Fenton, M.J. TLRs: differential adapter utilization by toll-like receptors mediates TLR-specific patterns of gene expression. Mol. Interv. 3, 466-477 (2003).
    • (2003) Mol. Interv. , vol.3 , pp. 466-477
    • Vogel, S.N.1    Fitzgerald, K.A.2    Fenton, M.J.3
  • 47
    • 3242798925 scopus 로고    scopus 로고
    • Forward genetic dissection of afferent immunity: The role of TIR adapter proteins in innate and adaptive immune responses
    • Beutler, B., Hoebe, K. & Shamel, L. Forward genetic dissection of afferent immunity: the role of TIR adapter proteins in innate and adaptive immune responses. C. R. Biol. 327, 571-580 (2004).
    • (2004) C. R. Biol. , vol.327 , pp. 571-580
    • Beutler, B.1    Hoebe, K.2    Shamel, L.3
  • 48
    • 1642278750 scopus 로고    scopus 로고
    • Identification of a TLR4- and TRIF-dependent activation program of dendritic cells
    • Weighardt, H. et al. Identification of a TLR4- and TRIF-dependent activation program of dendritic cells. Eur. J. Immunol. 34, 558-564 (2004).
    • (2004) Eur. J. Immunol. , vol.34 , pp. 558-564
    • Weighardt, H.1
  • 49
    • 0034927826 scopus 로고    scopus 로고
    • Sepsis and evolution of the innate immune response
    • discussion S6-7
    • Beutler, B. & Poltorak, A. Sepsis and evolution of the innate immune response. Crit. Care Med. 29, S2-6; discussion S6-7 (2001).
    • (2001) Crit. Care Med. , vol.29
    • Beutler, B.1    Poltorak, A.2
  • 50
    • 0141927167 scopus 로고    scopus 로고
    • The Toll-like receptors and their role in septic shock
    • Cristofaro, P. & Opal, S.M. The Toll-like receptors and their role in septic shock. Expert Opin. Ther. Targets 7, 603-612 (2003).
    • (2003) Expert Opin. Ther. Targets , vol.7 , pp. 603-612
    • Cristofaro, P.1    Opal, S.M.2
  • 51
    • 0015619335 scopus 로고
    • Identification of a novel cell type in peripheral lymphoid organs of mice. I. Morphology, quantitation, tissue distribution
    • Steinman, R.M. & Cohn, Z.A. Identification of a novel cell type in peripheral lymphoid organs of mice. I. Morphology, quantitation, tissue distribution. J. Exp. Med. 137, 1142-1162 (1973).
    • (1973) J. Exp. Med. , vol.137 , pp. 1142-1162
    • Steinman, R.M.1    Cohn, Z.A.2
  • 52
    • 0032546352 scopus 로고    scopus 로고
    • Dendritic cells and the control of immunity
    • Banchereau, J. & Steinman, R.M. Dendritic cells and the control of immunity. Nature 392, 245-252 (1998).
    • (1998) Nature , vol.392 , pp. 245-252
    • Banchereau, J.1    Steinman, R.M.2
  • 53
    • 0035838979 scopus 로고    scopus 로고
    • Dendritic cell subsets and lineages, and their functions in innate and adaptive immunity
    • Liu, Y.J. Dendritic cell subsets and lineages, and their functions in innate and adaptive immunity. Cell 106, 259-262 (2001).
    • (2001) Cell , vol.106 , pp. 259-262
    • Liu, Y.J.1
  • 54
    • 0036378114 scopus 로고    scopus 로고
    • Experimental models linking dendritic cell lineage, phenotype and function
    • Fazekas De St Groth, B. et al. Experimental models linking dendritic cell lineage, phenotype and function. Immunol. Cell Biol. 80, 469-476 (2002).
    • (2002) Immunol. Cell Biol. , vol.80 , pp. 469-476
    • De Fazekas St Groth, B.1
  • 55
    • 0142166682 scopus 로고    scopus 로고
    • Origin, precursors and differentiation of mouse dendritic cells
    • Ardavin, C. Origin, precursors and differentiation of mouse dendritic cells. Nat. Rev. Immunol. 3, 582-590 (2003).
    • (2003) Nat. Rev. Immunol. , vol.3 , pp. 582-590
    • Ardavin, C.1
  • 56
    • 0041846758 scopus 로고    scopus 로고
    • Murine dendritic cell development: Difficulties associated with subset analysis
    • Wilson, H.L. & O'Neill, H.C. Murine dendritic cell development: difficulties associated with subset analysis. Immunol. Cell Biol. 81, 239-246 (2003).
    • (2003) Immunol. Cell Biol. , vol.81 , pp. 239-246
    • Wilson, H.L.1    O'Neill, H.C.2
  • 57
    • 0035903288 scopus 로고    scopus 로고
    • Subsets of human dendritic cell precursors express different toll-like receptors and respond to different microbial antigens
    • Kadowaki, N. et al. Subsets of human dendritic cell precursors express different toll-like receptors and respond to different microbial antigens. J. Exp. Med. 194, 863-869 (2001).
    • (2001) J. Exp. Med. , vol.194 , pp. 863-869
    • Kadowaki, N.1
  • 58
    • 0035179882 scopus 로고    scopus 로고
    • Specialization and complementarity in microbial molecule recognition by human myeloid and plasmacytoid dendritic cells
    • Jarrossay, D., Napolitani, G., Colonna, M., Sallusto, F. & Lanzavecchia, A. Specialization and complementarity in microbial molecule recognition by human myeloid and plasmacytoid dendritic cells. Eur. J. Immunol. 31, 3388-3393 (2001).
    • (2001) Eur. J. Immunol. , vol.31 , pp. 3388-3393
    • Jarrossay, D.1    Napolitani, G.2    Colonna, M.3    Sallusto, F.4    Lanzavecchia, A.5
  • 59
    • 0037738569 scopus 로고    scopus 로고
    • + DC correlates with unresponsiveness to imidazoquinolines
    • + DC correlates with unresponsiveness to imidazoquinolines. Eur. J. Immunol. 33, 827-833 (2003).
    • (2003) Eur. J. Immunol. , vol.33 , pp. 827-833
    • Edwards, A.D.1
  • 60
    • 0022640843 scopus 로고
    • Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins
    • Mosmann, T.R., Cherwinski, H., Bond, M.W., Giedlin, M.A. & Coffman, R.L. Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins. J. Immunol. 136, 2348-2357 (1986).
    • (1986) J. Immunol. , vol.136 , pp. 2348-2357
    • Mosmann, T.R.1    Cherwinski, H.2    Bond, M.W.3    Giedlin, M.A.4    Coffman, R.L.5
  • 61
    • 0024325070 scopus 로고
    • Heterogeneity of cytokine secretion patterns and functions of helper T cells
    • Mosmann, T.R. & Coffman, R.L. Heterogeneity of cytokine secretion patterns and functions of helper T cells. Adv. Immunol. 46, 111-147 (1989).
    • (1989) Adv. Immunol. , vol.46 , pp. 111-147
    • Mosmann, T.R.1    Coffman, R.L.2
  • 63
    • 0036831673 scopus 로고    scopus 로고
    • The immunology of susceptibility and resistance to Leishmania major in mice
    • Sacks, D. & Noben-Trauth, N. The immunology of susceptibility and resistance to Leishmania major in mice. Nat. Rev. Immunol. 2, 845-858 (2002).
    • (2002) Nat. Rev. Immunol. , vol.2 , pp. 845-858
    • Sacks, D.1    Noben-Trauth, N.2
  • 65
    • 0034677646 scopus 로고    scopus 로고
    • H1 lineage commitment
    • H1 lineage commitment. Cell 100, 655-669 (2000).
    • (2000) Cell , vol.100 , pp. 655-669
    • Szabo, S.J.1
  • 66
    • 0030810155 scopus 로고    scopus 로고
    • H2 cytokine gene expression in CD4 T cells
    • H2 cytokine gene expression in CD4 T cells. Cell 89, 587-596 (1997).
    • (1997) Cell , vol.89 , pp. 587-596
    • Zheng, W.1    Flavell, R.A.2
  • 67
    • 0032212793 scopus 로고    scopus 로고
    • H1 development mediated by GATA-3 through an IL-4-independent mechanism
    • H1 development mediated by GATA-3 through an IL-4-independent mechanism. Immunity 9, 745-755 (1998).
    • (1998) Immunity , vol.9 , pp. 745-755
    • Ouyang, W.1
  • 68
    • 0035500862 scopus 로고    scopus 로고
    • Lipopolysaccharides from distinct pathogens induce different classes of immune responses in vivo
    • Pulendran, B. et al. Lipopolysaccharides from distinct pathogens induce different classes of immune responses in vivo. J. Immunol. 167, 5067-5076 (2001).
    • (2001) J. Immunol. , vol.167 , pp. 5067-5076
    • Pulendran, B.1
  • 69
    • 2942516628 scopus 로고    scopus 로고
    • Modulating vaccine responses with dendritic cells and Toll-like receptors
    • Pulendran, B. Modulating vaccine responses with dendritic cells and Toll-like receptors. Immunol. Rev. 199, 227-250 (2004).
    • (2004) Immunol. Rev. , vol.199 , pp. 227-250
    • Pulendran, B.1
  • 70
    • 0037061453 scopus 로고    scopus 로고
    • Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors
    • Leadbetter, E.A. et al. Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors. Nature 416, 603-607 (2002).
    • (2002) Nature , vol.416 , pp. 603-607
    • Leadbetter, E.A.1
  • 71
    • 3142676434 scopus 로고    scopus 로고
    • The stimulation of Toll-like receptors by nuclear antigens: A link between apoptosis and autoimmunity
    • Marshak-Rothstein, A., Busconi, L., Rifkin, I.R. & Viglianti, G.A. The stimulation of Toll-like receptors by nuclear antigens: a link between apoptosis and autoimmunity. Rheum. Dis. Clin. North Am. 30, 559-74, ix (2004).
    • (2004) Rheum. Dis. Clin. North Am. , vol.30 , pp. 559-574
    • Marshak-Rothstein, A.1    Busconi, L.2    Rifkin, I.R.3    Viglianti, G.A.4
  • 72
    • 0036318851 scopus 로고    scopus 로고
    • Bacterial CpG-DNA and lipopolysaccharides activate Toll-like receptors at distinct cellular compartments
    • Ahmad-Nejad, P. et al. Bacterial CpG-DNA and lipopolysaccharides activate Toll-like receptors at distinct cellular compartments. Eur. J. Immunol. 32, 1958-1968 (2002).
    • (2002) Eur. J. Immunol. , vol.32 , pp. 1958-1968
    • Ahmad-Nejad, P.1
  • 73
    • 4344627821 scopus 로고    scopus 로고
    • Endogenous ligands of Toll-like receptors
    • Tsan, M.F. & Gao, B. Endogenous ligands of Toll-like receptors. J. Leukoc. Biol. 76, 514-519 (2004).
    • (2004) J. Leukoc. Biol. , vol.76 , pp. 514-519
    • Tsan, M.F.1    Gao, B.2
  • 74
    • 0036623112 scopus 로고    scopus 로고
    • DC-SIGN, a C-type lectin on dendritic cells that unveils many aspects of dendritic cell biology
    • Geijtenbeek, T.B., Engering, A. & Van Kooyk, Y. DC-SIGN, a C-type lectin on dendritic cells that unveils many aspects of dendritic cell biology. J. Leukoc. Biol. 71, 921-931 (2002).
    • (2002) J. Leukoc. Biol. , vol.71 , pp. 921-931
    • Geijtenbeek, T.B.1    Engering, A.2    Van Kooyk, Y.3
  • 75
    • 0037184995 scopus 로고    scopus 로고
    • Pattern recognition receptors: Doubling up for the innate immune response
    • Gordon, S. Pattern recognition receptors: doubling up for the innate immune response. Cell 111, 927-930 (2002).
    • (2002) Cell , vol.111 , pp. 927-930
    • Gordon, S.1
  • 76
    • 0042307304 scopus 로고    scopus 로고
    • Viral infection switches non-plasmacytoid dendritic cells into high interferon producers
    • Diebold, S.S. et al. Viral infection switches non-plasmacytoid dendritic cells into high interferon producers. Nature 424, 324-328 (2003).
    • (2003) Nature , vol.424 , pp. 324-328
    • Diebold, S.S.1
  • 77
    • 0034658658 scopus 로고    scopus 로고
    • Type I interferon as a powerful adjuvant for monocyte-derived dendritic cell development and activity in vitro and in Hu-PBL-SCID mice
    • Santini, S.M. et al. Type I interferon as a powerful adjuvant for monocyte-derived dendritic cell development and activity in vitro and in Hu-PBL-SCID mice. J. Exp. Med. 191, 1777-1788 (2000).
    • (2000) J. Exp. Med. , vol.191 , pp. 1777-1788
    • Santini, S.M.1
  • 78
    • 0033966740 scopus 로고    scopus 로고
    • The control of T cell responses by dendritic cell subsets
    • Reid, S.D., Penna, G. & Adorini, L. The control of T cell responses by dendritic cell subsets. Curr. Opin. Immunol. 12, 114-121 (2000).
    • (2000) Curr. Opin. Immunol. , vol.12 , pp. 114-121
    • Reid, S.D.1    Penna, G.2    Adorini, L.3
  • 79
    • 0034919938 scopus 로고    scopus 로고
    • Dendritic cell lineage, plasticity and cross-regulation
    • Liu, Y.J., Kanzler, H., Soumelis, V. & Gilliet, M. Dendritic cell lineage, plasticity and cross-regulation. Nat. Immunol. 2, 585-589 (2001).
    • (2001) Nat. Immunol. , vol.2 , pp. 585-589
    • Liu, Y.J.1    Kanzler, H.2    Soumelis, V.3    Gilliet, M.4
  • 80
    • 3042521047 scopus 로고    scopus 로고
    • H2 responses with microbes, dendritic cells, and pathogen recognition receptors
    • H2 responses with microbes, dendritic cells, and pathogen recognition receptors. Immunol. Res. 29, 187-196 (2004).
    • (2004) Immunol. Res. , vol.29 , pp. 187-196
    • Pulendran, B.1
  • 82
    • 0034670385 scopus 로고    scopus 로고
    • Development of CD8α-positive dendritic cells from a common myeloid progenitor
    • Traver, D. et al. Development of CD8α-positive dendritic cells from a common myeloid progenitor. Science 290, 2152-2154 (2000).
    • (2000) Science , vol.290 , pp. 2152-2154
    • Traver, D.1
  • 83
    • 0035383775 scopus 로고    scopus 로고
    • Dendritic cell potentials of early lymphoid and myeloid progenitors
    • Manz, M.G., Traver, D., Miyamoto, T., Weissman, I.L. & Akashi, K. Dendritic cell potentials of early lymphoid and myeloid progenitors. Blood 97, 3333-3341 (2001).
    • (2001) Blood , vol.97 , pp. 3333-3341
    • Manz, M.G.1    Traver, D.2    Miyamoto, T.3    Weissman, I.L.4    Akashi, K.5
  • 84
    • 0035761466 scopus 로고    scopus 로고
    • Development of thymic and splenic dendritic cell populations from different hemopoietic precursors
    • Wu, L. et al. Development of thymic and splenic dendritic cell populations from different hemopoietic precursors. Blood 98, 3376-3382 (2001).
    • (2001) Blood , vol.98 , pp. 3376-3382
    • Wu, L.1
  • 85
    • 0034672034 scopus 로고    scopus 로고
    • The development, maturation, and turnover rate of mouse spleen dendritic cell populations
    • Kamath, A.T. et al. The development, maturation, and turnover rate of mouse spleen dendritic cell populations. J. Immunol. 165, 6762-6770 (2000).
    • (2000) J. Immunol. , vol.165 , pp. 6762-6770
    • Kamath, A.T.1
  • 86
    • 0038156226 scopus 로고    scopus 로고
    • + mouse spleen dendritic cells do not originate from the CD8α - Dendritic cell subset
    • + mouse spleen dendritic cells do not originate from the CD8α - dendritic cell subset. Blood 102, 601-604 (2003).
    • (2003) Blood , vol.102 , pp. 601-604
    • Naik, S.1    Vremec, D.2    Wu, L.3    O'Keeffe, M.4    Shortman, K.5
  • 87
    • 0037307668 scopus 로고    scopus 로고
    • ICSBP/IRF-8 retrovirus transduction rescues dendritic cell development in vitro
    • Tsujimura, H. et al. ICSBP/IRF-8 retrovirus transduction rescues dendritic cell development in vitro. Blood 101, 961-969 (2003).
    • (2003) Blood , vol.101 , pp. 961-969
    • Tsujimura, H.1
  • 88
    • 0037220671 scopus 로고    scopus 로고
    • Essential role for ICSBP in the in vivo development of murine CD8α+ dendritic cells
    • Aliberti, J. et al. Essential role for ICSBP in the in vivo development of murine CD8α+ dendritic cells. Blood 101, 305-310 (2003).
    • (2003) Blood , vol.101 , pp. 305-310
    • Aliberti, J.1
  • 89
    • 0033546053 scopus 로고    scopus 로고
    • The nature of the principal type 1 interferon-producing cells in human blood
    • Siegal, F.P. et al. The nature of the principal type 1 interferon-producing cells in human blood. Science 284, 1835-1837 (1999).
    • (1999) Science , vol.284 , pp. 1835-1837
    • Siegal, F.P.1
  • 90
    • 0034679566 scopus 로고    scopus 로고
    • Natural interferon α/β -producing cells link innate and adaptive immunity
    • Kadowaki, N., Antonenko, S., Lau, J.Y. & Liu, Y.J. Natural interferon α/β -producing cells link innate and adaptive immunity. J. Exp. Med. 192, 219-226 (2000).
    • (2000) J. Exp. Med. , vol.192 , pp. 219-226
    • Kadowaki, N.1    Antonenko, S.2    Lau, J.Y.3    Liu, Y.J.4
  • 91
    • 0035202483 scopus 로고    scopus 로고
    • Mouse type I IFN-producing cells are immature APCs with plasmacytoid morphology
    • Asselin-Paturel, C. et al. Mouse type I IFN-producing cells are immature APCs with plasmacytoid morphology. Nat. Immunol. 2, 1144-1150 (2001).
    • (2001) Nat. Immunol. , vol.2 , pp. 1144-1150
    • Asselin-Paturel, C.1
  • 92
    • 0037387403 scopus 로고    scopus 로고
    • Dendritic cell responses to early murine cytomegalovirus infection: Subset functional specialization and differential regulation by interferon alpha/beta
    • Dalod, M. et al. Dendritic cell responses to early murine cytomegalovirus infection: subset functional specialization and differential regulation by interferon alpha/beta. J. Exp. Med. 197, 885-898 (2003).
    • (2003) J. Exp. Med. , vol.197 , pp. 885-898
    • Dalod, M.1
  • 93
    • 4644342017 scopus 로고    scopus 로고
    • MHC class II expression is differentially regulated in plasmacytoid and conventional dendritic cells
    • LeibundGut-Landmann, S., Waldburger, J.M., Reis e Sousa, C., Acha-Orbea, H. & Reith, W. MHC class II expression is differentially regulated in plasmacytoid and conventional dendritic cells. Nat. Immunol. 5, 899-908 (2004).
    • (2004) Nat. Immunol. , vol.5 , pp. 899-908
    • Leibundgut-Landmann, S.1    Waldburger, J.M.2    Reis E Sousa, C.3    Acha-Orbea, H.4    Reith, W.5
  • 94
    • 0033582629 scopus 로고    scopus 로고
    • Reciprocal control of T helper cell and dendritic cell differentiation
    • Rissoan, M.C. et al. Reciprocal control of T helper cell and dendritic cell differentiation. Science 283, 1183-1186 (1999).
    • (1999) Science , vol.283 , pp. 1183-1186
    • Rissoan, M.C.1
  • 96
    • 0036927106 scopus 로고    scopus 로고
    • Differential migration behavior and chemokine production by myeloid and plasmacytoid dendritic cells
    • Penna, G., Vulcano, M., Sozzani, S. & Adorini, L. Differential migration behavior and chemokine production by myeloid and plasmacytoid dendritic cells. Hum. Immunol. 63, 1164-1171 (2002).
    • (2002) Hum. Immunol. , vol.63 , pp. 1164-1171
    • Penna, G.1    Vulcano, M.2    Sozzani, S.3    Adorini, L.4
  • 97
    • 0034619794 scopus 로고    scopus 로고
    • A Toll-like receptor recognizes bacterial DNA
    • Hemmi, H. et al. A Toll-like receptor recognizes bacterial DNA. Nature 408, 740-745 (2000).
    • (2000) Nature , vol.408 , pp. 740-745
    • Hemmi, H.1
  • 98
    • 0037443644 scopus 로고    scopus 로고
    • The roles of Toll-like receptor 9, MyD88, and DNA-dependent protein kinase catalytic subunit in the effects of two distinct CpG DNAs on dendritic cell subsets
    • Hemmi, H., Kaisho, T., Takeda, K. & Akira, S. The roles of Toll-like receptor 9, MyD88, and DNA-dependent protein kinase catalytic subunit in the effects of two distinct CpG DNAs on dendritic cell subsets. J. Immunol. 170, 3059-3064 (2003).
    • (2003) J. Immunol. , vol.170 , pp. 3059-3064
    • Hemmi, H.1    Kaisho, T.2    Takeda, K.3    Akira, S.4
  • 99
    • 0035112910 scopus 로고    scopus 로고
    • Enhancing vaccines with immune stimulatory CpG DNA
    • Krieg, A.M. & Davis, H.L. Enhancing vaccines with immune stimulatory CpG DNA. Curr. Opin. Mol. Ther. 3, 15-24 (2001).
    • (2001) Curr. Opin. Mol. Ther. , vol.3 , pp. 15-24
    • Krieg, A.M.1    Davis, H.L.2
  • 101
    • 0033749217 scopus 로고    scopus 로고
    • Mechanisms of immune stimulation by bacterial DNA
    • Pisetsky, D.S. Mechanisms of immune stimulation by bacterial DNA. Springer Semin. Immunopathol. 22, 21-33 (2000).
    • (2000) Springer Semin. Immunopathol. , vol.22 , pp. 21-33
    • Pisetsky, D.S.1
  • 102
  • 103
    • 3142720367 scopus 로고    scopus 로고
    • Essential role of lung plasmacytoid dendritic cells in preventing asthmatic reactions to harmless inhaled antigen
    • de Heer, H.J. et al. Essential role of lung plasmacytoid dendritic cells in preventing asthmatic reactions to harmless inhaled antigen. J. Exp. Med. 200, 89-98 (2004).
    • (2004) J. Exp. Med. , vol.200 , pp. 89-98
    • De Heer, H.J.1
  • 104
    • 0037039379 scopus 로고    scopus 로고
    • Avoiding horror autotoxicus: The importance of dendritic cells in peripheral T cell tolerance
    • Steinman, R.M. & Nussenzweig, M.C. Avoiding horror autotoxicus: the importance of dendritic cells in peripheral T cell tolerance. Proc. Natl. Acad. Sci. USA 99, 351-358 (2002).
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 351-358
    • Steinman, R.M.1    Nussenzweig, M.C.2
  • 105
    • 0037080938 scopus 로고    scopus 로고
    • Manipulation of dendritic cells for tolerance induction in transplantation and autoimmune disease
    • Lu, L. & Thomson, A.W. Manipulation of dendritic cells for tolerance induction in transplantation and autoimmune disease. Transplantation 73, S19-S22 (2002).
    • (2002) Transplantation , vol.73
    • Lu, L.1    Thomson, A.W.2
  • 107
    • 0024502409 scopus 로고
    • The thymus selects the useful, neglects the useless and destroys the harmful
    • von Boehmer, H., Teh, H.S. & Kisielow, P. The thymus selects the useful, neglects the useless and destroys the harmful. Immunol. Today 10, 57-61 (1989).
    • (1989) Immunol. Today , vol.10 , pp. 57-61
    • Von Boehmer, H.1    Teh, H.S.2    Kisielow, P.3
  • 108
    • 0031755882 scopus 로고    scopus 로고
    • Intrathymic expression of genes involved in organ specific autoimmune disease
    • Heath, V.L., Moore, N.C., Parnell, S.M. & Mason, D.W. Intrathymic expression of genes involved in organ specific autoimmune disease. J. Autoimmun. 11, 309-318 (1998).
    • (1998) J. Autoimmun. , vol.11 , pp. 309-318
    • Heath, V.L.1    Moore, N.C.2    Parnell, S.M.3    Mason, D.W.4
  • 109
    • 0033590981 scopus 로고    scopus 로고
    • Autoimmune regulator is expressed in the cells regulating immune tolerance in thymus medulla
    • Heino, M. et al. Autoimmune regulator is expressed in the cells regulating immune tolerance in thymus medulla. Biochem. Biophys. Res. Commun. 257, 821-825 (1999).
    • (1999) Biochem. Biophys. Res. Commun. , vol.257 , pp. 821-825
    • Heino, M.1
  • 110
    • 0035171545 scopus 로고    scopus 로고
    • Promiscuous gene expression in medullary thymic epithelial cells mirrors the peripheral self
    • Derbinski, J., Schulte, A., Kyewski, B. & Klein, L. Promiscuous gene expression in medullary thymic epithelial cells mirrors the peripheral self. Nat. Immunol. 2, 1032-1039 (2001).
    • (2001) Nat. Immunol. , vol.2 , pp. 1032-1039
    • Derbinski, J.1    Schulte, A.2    Kyewski, B.3    Klein, L.4
  • 111
    • 0037112047 scopus 로고    scopus 로고
    • Projection of an immunological self shadow within the thymus by the aire protein
    • Anderson, M.S. et al. Projection of an immunological self shadow within the thymus by the aire protein. Science 298, 1395-1401 (2002).
    • (2002) Science , vol.298 , pp. 1395-1401
    • Anderson, M.S.1
  • 113
    • 4544258485 scopus 로고    scopus 로고
    • Self-representation in the thymus: An extended view
    • Kyewski, B. & Derbinski, J. Self-representation in the thymus: an extended view. Nat. Rev. Immunol. 4, 688-698 (2004).
    • (2004) Nat. Rev. Immunol. , vol.4 , pp. 688-698
    • Kyewski, B.1    Derbinski, J.2
  • 114
    • 0032230236 scopus 로고    scopus 로고
    • Common mutations in autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy patients of different origins
    • Scott, H.S. et al. Common mutations in autoimmune polyendocrinopathy- candidiasis-ectodermal dystrophy patients of different origins. Mol. Endocrinol. 12, 1112-1119 (1998).
    • (1998) Mol. Endocrinol. , vol.12 , pp. 1112-1119
    • Scott, H.S.1
  • 115
    • 0031753977 scopus 로고    scopus 로고
    • A common mutation in Sardinian autoimmune polyendocrinopathy-candidiasis- ectodermal dystrophy patients
    • Rosatelli, M.C. et al. A common mutation in Sardinian autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy patients. Hum. Genet. 103, 428-434 (1998).
    • (1998) Hum. Genet. , vol.103 , pp. 428-434
    • Rosatelli, M.C.1
  • 116
    • 7244227646 scopus 로고    scopus 로고
    • Gene dosage-limiting role of Aire in thymic expression, clonal deletion, and organ-specific autoimmunity
    • Liston, A. et al. Gene dosage-limiting role of Aire in thymic expression, clonal deletion, and organ-specific autoimmunity. J. Exp. Med. 200, 1015-1026 (2004).
    • (2004) J. Exp. Med. , vol.200 , pp. 1015-1026
    • Liston, A.1
  • 117
    • 3042538779 scopus 로고    scopus 로고
    • New autoimmune genes and the pathogenesis of type 1 diabetes
    • Hornum, L. & Markholst, H. New autoimmune genes and the pathogenesis of type 1 diabetes. Curr. Diab. Rep. 4, 135-142 (2004).
    • (2004) Curr. Diab. Rep. , vol.4 , pp. 135-142
    • Hornum, L.1    Markholst, H.2
  • 119
    • 0034614886 scopus 로고    scopus 로고
    • The induction of tolerance by dendritic cells that have captured apoptotic cells
    • Steinman, R.M., Turley, S., Mellman, I. & Inaba, K. The induction of tolerance by dendritic cells that have captured apoptotic cells. J. Exp. Med. 191, 411-416 (2000).
    • (2000) J. Exp. Med. , vol.191 , pp. 411-416
    • Steinman, R.M.1    Turley, S.2    Mellman, I.3    Inaba, K.4
  • 120
    • 0035059416 scopus 로고    scopus 로고
    • Cross-presentation, dendritic cells, tolerance and immunity
    • Heath, W.R. & Carbone, F.R. Cross-presentation, dendritic cells, tolerance and immunity. Annu. Rev. Immunol. 19, 47-64 (2001).
    • (2001) Annu. Rev. Immunol. , vol.19 , pp. 47-64
    • Heath, W.R.1    Carbone, F.R.2
  • 121
    • 0035903326 scopus 로고    scopus 로고
    • Dendritic cells induce peripheral T cell unresponsiveness under steady state conditions in vivo
    • Hawiger, D. et al. Dendritic cells induce peripheral T cell unresponsiveness under steady state conditions in vivo. J. Exp. Med. 194, 769-779 (2001).
    • (2001) J. Exp. Med. , vol.194 , pp. 769-779
    • Hawiger, D.1
  • 122
    • 0037122011 scopus 로고    scopus 로고
    • + T cell tolerance
    • + T cell tolerance. J. Exp. Med. 196, 1627-1638 (2002).
    • (2002) J. Exp. Med. , vol.196 , pp. 1627-1638
    • Bonifaz, L.1
  • 123
    • 0037099710 scopus 로고    scopus 로고
    • On the role of dendritic cells in peripheral T cell tolerance and modulation of autoimmunity
    • Legge, K.L. et al. On the role of dendritic cells in peripheral T cell tolerance and modulation of autoimmunity. J. Exp. Med. 196, 217-227 (2002).
    • (2002) J. Exp. Med. , vol.196 , pp. 217-227
    • Legge, K.L.1
  • 124
    • 0028144631 scopus 로고
    • Functional recognition of in vivo processed self antigen
    • Stockinger, B. & Hausmann, B. Functional recognition of in vivo processed self antigen. Int. Immunol. 6, 247-254 (1994).
    • (1994) Int. Immunol. , vol.6 , pp. 247-254
    • Stockinger, B.1    Hausmann, B.2
  • 125
    • 0034614894 scopus 로고    scopus 로고
    • A discrete subpopulation of dendritic cells transports apoptotic intestinal epithelial cells to T cell areas of mesenteric lymph nodes
    • Huang, F.P. et al. A discrete subpopulation of dendritic cells transports apoptotic intestinal epithelial cells to T cell areas of mesenteric lymph nodes. J. Exp. Med. 191, 435-444 (2000).
    • (2000) J. Exp. Med. , vol.191 , pp. 435-444
    • Huang, F.P.1
  • 126
    • 0037152162 scopus 로고    scopus 로고
    • Constitutive presentation of a natural tissue autoantigen exclusively by dendritic cells in the draining lymph node
    • Scheinecker, C., McHugh, R., Shevach, E.M. & Germain, R.N. Constitutive presentation of a natural tissue autoantigen exclusively by dendritic cells in the draining lymph node. J. Exp. Med. 196, 1079-1090 (2002).
    • (2002) J. Exp. Med. , vol.196 , pp. 1079-1090
    • Scheinecker, C.1    McHugh, R.2    Shevach, E.M.3    Germain, R.N.4
  • 127
    • 0037307921 scopus 로고    scopus 로고
    • Inhibitory feedback loop between tolerogenic dendritic cells and regulatory T cells in transplant tolerance
    • Min, W.P. et al. Inhibitory feedback loop between tolerogenic dendritic cells and regulatory T cells in transplant tolerance. J. Immunol. 170, 1304-1312 (2003).
    • (2003) J. Immunol. , vol.170 , pp. 1304-1312
    • Min, W.P.1
  • 128
    • 0042512461 scopus 로고    scopus 로고
    • + regulatory T cells by antigen-processing dendritic cells
    • + regulatory T cells by antigen-processing dendritic cells. J. Exp. Med. 198, 235-247 (2003).
    • (2003) J. Exp. Med. , vol.198 , pp. 235-247
    • Yamazaki, S.1
  • 129
    • 0041884743 scopus 로고    scopus 로고
    • Continuous activation of autoreactive CD4+CD25+ regulatory T cells in the steady state
    • Fisson, S. et al. Continuous activation of autoreactive CD4+CD25+ regulatory T cells in the steady state. J. Exp. Med. 198, 737-746 (2003).
    • (2003) J. Exp. Med. , vol.198 , pp. 737-746
    • Fisson, S.1
  • 130
    • 0037565445 scopus 로고    scopus 로고
    • Dendritic cell function in vivo during the steady state: A role in peripheral tolerance
    • Steinman, R.M. et al. Dendritic cell function in vivo during the steady state: a role in peripheral tolerance. Ann NY Acad Sci 987, 15-25 (2003).
    • (2003) Ann. NY Acad. Sci. , vol.987 , pp. 15-25
    • Steinman, R.M.1
  • 131
    • 0026481133 scopus 로고
    • Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor
    • Inaba, K. et al. Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor. J. Exp. Med. 176, 1693-1702 (1992).
    • (1992) J. Exp. Med. , vol.176 , pp. 1693-1702
    • Inaba, K.1
  • 132
    • 0030868523 scopus 로고    scopus 로고
    • Dramatic numerical increase of functionally mature dendritic cells in FLT3 ligand-treated mice
    • Maraskovsky, E. et al. Dramatic numerical increase of functionally mature dendritic cells in FLT3 ligand-treated mice. Adv. Exp. Med. Biol. 417, 33-40 (1997).
    • (1997) Adv. Exp. Med. Biol. , vol.417 , pp. 33-40
    • Maraskovsky, E.1
  • 133
    • 0032849641 scopus 로고    scopus 로고
    • Dendritic cells: Expansion and differentiation with hematopoietic growth factors
    • Young, J.W. Dendritic cells: expansion and differentiation with hematopoietic growth factors. Curr. Opin. Hematol. 6, 135-144 (1999).
    • (1999) Curr. Opin. Hematol. , vol.6 , pp. 135-144
    • Young, J.W.1
  • 134
    • 0035991491 scopus 로고    scopus 로고
    • Cytokines in the generation and maturation of dendritic cells: Recent advances
    • Zou, G.M. & Tam, Y.K. Cytokines in the generation and maturation of dendritic cells: recent advances. Eur. Cytokine Netw. 13, 186-199 (2002).
    • (2002) Eur. Cytokine Netw. , vol.13 , pp. 186-199
    • Zou, G.M.1    Tam, Y.K.2
  • 135
    • 0035889647 scopus 로고    scopus 로고
    • Active immunization against cancer with dendritic cells: The near future
    • Steinman, R.M. & Dhodapkar, M. Active immunization against cancer with dendritic cells: the near future. Int. J. Cancer 94, 459-473 (2001).
    • (2001) Int. J. Cancer , vol.94 , pp. 459-473
    • Steinman, R.M.1    Dhodapkar, M.2
  • 138
    • 0025872742 scopus 로고
    • Adjuvant-independent immunization by immunotargeting antigens to MHC and non-MHC determinants in vivo
    • Carayanniotis, G., Skea, D.L., Luscher, M.A. & Barber, B.H. Adjuvant-independent immunization by immunotargeting antigens to MHC and non-MHC determinants in vivo. Mol. Immunol. 28, 261-267 (1991).
    • (1991) Mol. Immunol. , vol.28 , pp. 261-267
    • Carayanniotis, G.1    Skea, D.L.2    Luscher, M.A.3    Barber, B.H.4
  • 139
    • 0030586611 scopus 로고    scopus 로고
    • Dendritic cells can present antigen in vivo in a tolerogenic or immunogenic fashion
    • Finkelman, F.D., Lees, A., Birnbaum, R., Gause, W.C. & Morris, S.C. Dendritic cells can present antigen in vivo in a tolerogenic or immunogenic fashion. J. Immunol. 157, 1406-1414 (1996).
    • (1996) J. Immunol. , vol.157 , pp. 1406-1414
    • Finkelman, F.D.1    Lees, A.2    Birnbaum, R.3    Gause, W.C.4    Morris, S.C.5
  • 140
    • 0033404987 scopus 로고    scopus 로고
    • Get into the groove! Targeting antigens to MHC class II
    • van Bergen, J. et al. Get into the groove! Targeting antigens to MHC class II. Immunol. Rev. 172, 87-96 (1999).
    • (1999) Immunol. Rev. , vol.172 , pp. 87-96
    • Van Bergen, J.1
  • 141
    • 0016762220 scopus 로고
    • Natural killer cells in the mouse. I. Cytotoxic cells with specificity for mouse Moloney leukemia cells. Specificity and distribution according to genotype
    • Kiessling, R., Klein, E. & Wigzell, H. Natural killer cells in the mouse. I. Cytotoxic cells with specificity for mouse Moloney leukemia cells. Specificity and distribution according to genotype. Eur. J. Immunol. 5, 112-117 (1975).
    • (1975) Eur. J. Immunol. , vol.5 , pp. 112-117
    • Kiessling, R.1    Klein, E.2    Wigzell, H.3
  • 142
    • 0017832009 scopus 로고    scopus 로고
    • Natural killer cells in the mouse: An alternative immune surveillance mechanism?
    • 197B
    • Kiessling, R. & Haller, O. Natural killer cells in the mouse: an alternative immune surveillance mechanism? Contemp. Top. Immunobiol. 8, 171-201 (197B).
    • Contemp. Top. Immunobiol. , vol.8 , pp. 171-201
    • Kiessling, R.1    Haller, O.2
  • 144
    • 0026628008 scopus 로고
    • MHC class I alloantigen specificity of Ly-49+ IL-2-activated natural killer cells
    • Karlhofer, F.M., Ribaudo, R.K. & Yokoyama, W.M. MHC class I alloantigen specificity of Ly-49+ IL-2-activated natural killer cells. Nature 358, 66-70 (1992).
    • (1992) Nature , vol.358 , pp. 66-70
    • Karlhofer, F.M.1    Ribaudo, R.K.2    Yokoyama, W.M.3
  • 145
    • 0027284452 scopus 로고
    • P58 molecules as putative receptors for major histocompatibility complex (MHC) class I molecules in human natural killer (NK) cells. Antip58 antibodies reconstitute lysis of MHC class I-protected cells in NK clones displaying different specificities
    • Moretta, A. et al. P58 molecules as putative receptors for major histocompatibility complex (MHC) class I molecules in human natural killer (NK) cells. Antip58 antibodies reconstitute lysis of MHC class I-protected cells in NK clones displaying different specificities. J. Exp. Med. 178, 597-604 (1993).
    • (1993) J. Exp. Med. , vol.178 , pp. 597-604
    • Moretta, A.1
  • 146
    • 0028332836 scopus 로고
    • NKB1: A natural killer cell receptor involved in the recognition of polymorphic HLA-B molecules
    • Litwin, V., Gumperz, J., Parham, P., Phillips, J.H. & Lanier, L.L. NKB1: a natural killer cell receptor involved in the recognition of polymorphic HLA-B molecules. J. Exp. Med. 180, 537-543 (1994).
    • (1994) J. Exp. Med. , vol.180 , pp. 537-543
    • Litwin, V.1    Gumperz, J.2    Parham, P.3    Phillips, J.H.4    Lanier, L.L.5
  • 147
    • 0028277286 scopus 로고
    • A natural killer cell receptor specific for a major histocompatibility complex class I molecule
    • Daniels, B.F., Karlhofer, F.M., Seaman, W.E. & Yokoyama, W.M. A natural killer cell receptor specific for a major histocompatibility complex class I molecule. J. Exp. Med. 180, 687-692 (1994).
    • (1994) J. Exp. Med. , vol.180 , pp. 687-692
    • Daniels, B.F.1    Karlhofer, F.M.2    Seaman, W.E.3    Yokoyama, W.M.4
  • 148
    • 0028029464 scopus 로고
    • Expression of different members of the Ly-49 gene family defines distinct natural killer cell subsets and cell adhesion properties
    • Brennan, J., Mager, D., Jefferies, W. & Takei, F. Expression of different members of the Ly-49 gene family defines distinct natural killer cell subsets and cell adhesion properties. J. Exp. Med. 180, 2287-2295 (1994).
    • (1994) J. Exp. Med. , vol.180 , pp. 2287-2295
    • Brennan, J.1    Mager, D.2    Jefferies, W.3    Takei, F.4
  • 149
    • 0029015726 scopus 로고
    • Molecular clones of the p58 NK cell receptor reveal immunoglobulin- related molecules with diversity in both the extra-and intracellular domains
    • Wagtmann, N. et al. Molecular clones of the p58 NK cell receptor reveal immunoglobulin-related molecules with diversity in both the extra-and intracellular domains. Immunity 2, 439-449 (1995).
    • (1995) Immunity , vol.2 , pp. 439-449
    • Wagtmann, N.1
  • 150
    • 0031944075 scopus 로고    scopus 로고
    • NK cell receptors
    • Lanier, L.L. NK cell receptors. Annu. Rev. Immunol. 16, 359-393 (1998).
    • (1998) Annu. Rev. Immunol. , vol.16 , pp. 359-393
    • Lanier, L.L.1
  • 151
    • 0038316337 scopus 로고    scopus 로고
    • Immune functions encoded by the natural killer gene complex
    • Yokoyama, W.M. & Plougastel, B.F. Immune functions encoded by the natural killer gene complex. Nat. Rev. Immunol. 3, 304-316 (2003).
    • (2003) Nat. Rev. Immunol. , vol.3 , pp. 304-316
    • Yokoyama, W.M.1    Plougastel, B.F.2
  • 152
    • 0142197631 scopus 로고    scopus 로고
    • Roles of the NKG2D immunoreceptor and its ligands
    • Raulet, D.H. Roles of the NKG2D immunoreceptor and its ligands. Nat. Rev. Immunol. 3, 781-790 (2003).
    • (2003) Nat. Rev. Immunol. , vol.3 , pp. 781-790
    • Raulet, D.H.1
  • 153
    • 3042569008 scopus 로고    scopus 로고
    • Learning how to discriminate between friends and enemies, a lesson from Natural Killer cells
    • Bottino, C., Moretta, L., Pende, D., Vitale, M. & Moretta, A. Learning how to discriminate between friends and enemies, a lesson from Natural Killer cells. Mol. Immunol. 41, 569-575 (2004).
    • (2004) Mol. Immunol. , vol.41 , pp. 569-575
    • Bottino, C.1    Moretta, L.2    Pende, D.3    Vitale, M.4    Moretta, A.5
  • 154
    • 0035056004 scopus 로고    scopus 로고
    • Regulation of the natural killer cell receptor repertoire
    • Raulet, D.H., Vance, R.E. & McMahon, C.W. Regulation of the natural killer cell receptor repertoire. Annu. Rev. Immunol. 19, 291-330 (2001).
    • (2001) Annu. Rev. Immunol. , vol.19 , pp. 291-330
    • Raulet, D.H.1    Vance, R.E.2    McMahon, C.W.3
  • 155
    • 0033957191 scopus 로고    scopus 로고
    • NK cell activation: Distinct stimulatory pathways counterbalancing inhibitory signals
    • Bakker, A.B., Wu, J., Phillips, J.H. & Lanier, L.L. NK cell activation: distinct stimulatory pathways counterbalancing inhibitory signals. Hum. Immunol. 61, 18-27 (2000).
    • (2000) Hum. Immunol. , vol.61 , pp. 18-27
    • Bakker, A.B.1    Wu, J.2    Phillips, J.H.3    Lanier, L.L.4
  • 156
    • 0035205995 scopus 로고    scopus 로고
    • Human natural killer cell receptors and signal transduction
    • Campbell, K.S. & Colonna, M. Human natural killer cell receptors and signal transduction. Int. Rev. Immunol. 20, 333-370 (2001).
    • (2001) Int. Rev. Immunol. , vol.20 , pp. 333-370
    • Campbell, K.S.1    Colonna, M.2
  • 157
    • 0037716818 scopus 로고    scopus 로고
    • Natural killer cell receptor signaling
    • Lanier, L.L. Natural killer cell receptor signaling. Curr. Opin. Immunol. 15, 308-314 (2003).
    • (2003) Curr. Opin. Immunol. , vol.15 , pp. 308-314
    • Lanier, L.L.1
  • 158
    • 0034904144 scopus 로고    scopus 로고
    • Ligands for natural killer cell receptors: Redundancy or specificity
    • Cerwenka, A. & Lanier, L.L. Ligands for natural killer cell receptors: redundancy or specificity. Immunol. Rev. 181, 158-169 (2001).
    • (2001) Immunol. Rev. , vol.181 , pp. 158-169
    • Cerwenka, A.1    Lanier, L.L.2
  • 159
    • 0042353905 scopus 로고    scopus 로고
    • Structure and function of natural killer cell surface receptors
    • Radaev, S. & Sun, P.D. Structure and function of natural killer cell surface receptors. Annu. Rev. Biophys. Biomol. Struct. 32, 93-114 (2003).
    • (2003) Annu. Rev. Biophys. Biomol. Struct. , vol.32 , pp. 93-114
    • Radaev, S.1    Sun, P.D.2
  • 160
    • 0026691106 scopus 로고
    • NK cells and T cells: Mirror images?
    • Versteeg, R. NK cells and T cells: mirror images? Immunol. Today 13, 244-247 (1992).
    • (1992) Immunol. Today , vol.13 , pp. 244-247
    • Versteeg, R.1
  • 161
    • 0032092633 scopus 로고    scopus 로고
    • From sabotage to camouflage: Viral evasion of cytotoxic T lymphocyte and natural killer cell-mediated immunity
    • Farrell, H.E. & Davis-Poynter, N.J. From sabotage to camouflage: viral evasion of cytotoxic T lymphocyte and natural killer cell-mediated immunity. Semin. Cell Dev. Biol. 9, 369-378 (1998).
    • (1998) Semin. Cell Dev. Biol. , vol.9 , pp. 369-378
    • Farrell, H.E.1    Davis-Poynter, N.J.2
  • 162
    • 0035046094 scopus 로고    scopus 로고
    • Viral immune evasion strategies and the underlying cell biology
    • Lorenzo, M.E., Ploegh, H.L. & Tirabassi, R.S. Viral immune evasion strategies and the underlying cell biology. Semin. Immunol. 13, 1-9 (2001).
    • (2001) Semin. Immunol. , vol.13 , pp. 1-9
    • Lorenzo, M.E.1    Ploegh, H.L.2    Tirabassi, R.S.3
  • 163
    • 0141960095 scopus 로고    scopus 로고
    • A survival game of hide and seek: Cytomegaloviruses and MHC class I antigen presentation pathways
    • Basta, S. & Bennink, J.R. A survival game of hide and seek: cytomegaloviruses and MHC class I antigen presentation pathways. Viral Immunol. 16, 231-242 (2003).
    • (2003) Viral Immunol. , vol.16 , pp. 231-242
    • Basta, S.1    Bennink, J.R.2
  • 164
    • 0028283971 scopus 로고
    • + T lymphocytes
    • + T lymphocytes. Cell 77, 525-535 (1994).
    • (1994) Cell , vol.77 , pp. 525-535
    • York, I.A.1
  • 165
    • 0029069681 scopus 로고
    • A viral inhibitor of peptide transporters for antigen presentation
    • Fruh, K. et al. A viral inhibitor of peptide transporters for antigen presentation. Nature 375, 415-418 (1995).
    • (1995) Nature , vol.375 , pp. 415-418
    • Fruh, K.1
  • 166
    • 1642538424 scopus 로고    scopus 로고
    • Human cytomegalovirus inhibits tapasin-dependent peptide loading and optimization of the MHC class I peptide cargo for immune evasion
    • Park, B. et al. Human cytomegalovirus inhibits tapasin-dependent peptide loading and optimization of the MHC class I peptide cargo for immune evasion. Immunity 20, 71-85 (2004).
    • (2004) Immunity , vol.20 , pp. 71-85
    • Park, B.1
  • 167
    • 0029915568 scopus 로고    scopus 로고
    • The human cytomegalovirus US11 gene product dislocates MHC class I heavy chains from the endoplasmic reticulum to the cytosol
    • Wiertz, E.J. et al. The human cytomegalovirus US11 gene product dislocates MHC class I heavy chains from the endoplasmic reticulum to the cytosol. Cell 84, 769-779 (1996).
    • (1996) Cell , vol.84 , pp. 769-779
    • Wiertz, E.J.1
  • 168
    • 0025300414 scopus 로고
    • In search of the 'missing self': MHC molecules and NK cell recognition
    • Ljunggren, H.G. & Karre, K. In search of the 'missing self': MHC molecules and NK cell recognition. Immunol. Today 11, 237-244 (1990).
    • (1990) Immunol. Today , vol.11 , pp. 237-244
    • Ljunggren, H.G.1    Karre, K.2
  • 169
    • 0029914911 scopus 로고    scopus 로고
    • Recognition of class I major histocompatibility complex molecules by Ly-49: Specificities and domain interactions
    • Brennan, J., Mahon, G., Mager, D.L., Jefferies, W.A. & Takei, F. Recognition of class I major histocompatibility complex molecules by Ly-49: specificities and domain interactions. J. Exp. Med. 183, 1553-1559 (1996).
    • (1996) J. Exp. Med. , vol.183 , pp. 1553-1559
    • Brennan, J.1    Mahon, G.2    Mager, D.L.3    Jefferies, W.A.4    Takei, F.5
  • 170
    • 0037172968 scopus 로고    scopus 로고
    • Recognition of a virus-encoded ligand by a natural killer cell activation receptor
    • Smith, H.R. et al. Recognition of a virus-encoded ligand by a natural killer cell activation receptor. Proc. Natl. Acad. Sci. USA 99, 8826-8831 (2002).
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 8826-8831
    • Smith, H.R.1
  • 171
    • 0345686735 scopus 로고    scopus 로고
    • Murine cytomegalovirus m157 mutation and variation leads to immune evasion of natural killer cells
    • Voigt, V. et al. Murine cytomegalovirus m157 mutation and variation leads to immune evasion of natural killer cells. Proc. Natl. Acad. Sci. USA 100, 13483-13488 (2003).
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 13483-13488
    • Voigt, V.1
  • 172
    • 0033618504 scopus 로고    scopus 로고
    • Activation of NK cells and T cells by NKG2D, a receptor for stress-inducible MICA
    • Bauer, S. et al. Activation of NK cells and T cells by NKG2D, a receptor for stress-inducible MICA. Science 285, 727-729 (1999).
    • (1999) Science , vol.285 , pp. 727-729
    • Bauer, S.1
  • 173
    • 0034252303 scopus 로고    scopus 로고
    • Ligands for the murine NKG2D receptor: Expression by tumor cells and activation of NK cells and macrophages
    • Diefenbach, A., Jamieson, A.M., Liu, S.D., Shastri, N. & Raulet, D.H. Ligands for the murine NKG2D receptor: expression by tumor cells and activation of NK cells and macrophages. Nat. Immunol. 1, 119-126 (2000).
    • (2000) Nat. Immunol. , vol.1 , pp. 119-126
    • Diefenbach, A.1    Jamieson, A.M.2    Liu, S.D.3    Shastri, N.4    Raulet, D.H.5
  • 174
    • 0034900287 scopus 로고    scopus 로고
    • The UL16-binding proteins, a novel family of MHC class I-related ligands for NKG2D, activate natural killer cell functions
    • Sutherland, C.L., Chalupny, N.J. & Cosman, D. The UL16-binding proteins, a novel family of MHC class I-related ligands for NKG2D, activate natural killer cell functions. Immunol. Rev. 181, 185-192 (2001).
    • (2001) Immunol. Rev. , vol.181 , pp. 185-192
    • Sutherland, C.L.1    Chalupny, N.J.2    Cosman, D.3
  • 175
    • 0037108353 scopus 로고    scopus 로고
    • Cutting edge: Murine UL16-binding protein-like transcript 1: A newly described transcript encoding a high-affinity ligand for murine NKG2D
    • Carayannopoulos, L.N., Naidenko, O.V., Fremont, D.H. & Yokoyama, W.M. Cutting edge: murine UL16-binding protein-like transcript 1: a newly described transcript encoding a high-affinity ligand for murine NKG2D. J. Immunol. 169, 4079-4083 (2002).
    • (2002) J. Immunol. , vol.169 , pp. 4079-4083
    • Carayannopoulos, L.N.1    Naidenko, O.V.2    Fremont, D.H.3    Yokoyama, W.M.4
  • 176
    • 0036155843 scopus 로고    scopus 로고
    • Tumor cell recognition by natural killer cells
    • Long, E.O. Tumor cell recognition by natural killer cells. Semin. Cancer Biol. 12, 57-61 (2002).
    • (2002) Semin. Cancer Biol. , vol.12 , pp. 57-61
    • Long, E.O.1
  • 177
    • 0036812626 scopus 로고    scopus 로고
    • The innate immune response to tumors and its role in the induction of T-cell immunity
    • Diefenbach, A. & Raulet, D.H. The innate immune response to tumors and its role in the induction of T-cell immunity. Immunol. Rev. 188, 9-21 (2002).
    • (2002) Immunol. Rev. , vol.188 , pp. 9-21
    • Diefenbach, A.1    Raulet, D.H.2
  • 178
    • 0037515740 scopus 로고    scopus 로고
    • NKG2D ligands: Unconventional MHC class I-like molecules exploited by viruses and cancer
    • Cerwenka, A. & Lanier, L.L. NKG2D ligands: unconventional MHC class I-like molecules exploited by viruses and cancer. Tissue Antigens 61, 335-343 (2003).
    • (2003) Tissue Antigens , vol.61 , pp. 335-343
    • Cerwenka, A.1    Lanier, L.L.2
  • 179
    • 0037126310 scopus 로고    scopus 로고
    • Tumour-derived soluble MIC ligands impair expression of NKG2D and T-cell activation
    • Groh, V., Wu, J., Yee, C. & Spies, T. Tumour-derived soluble MIC ligands impair expression of NKG2D and T-cell activation. Nature 419, 734-738 (2002).
    • (2002) Nature , vol.419 , pp. 734-738
    • Groh, V.1    Wu, J.2    Yee, C.3    Spies, T.4
  • 180
    • 0041737499 scopus 로고    scopus 로고
    • Functional expression and release of ligands for the activating immunoreceptor NKG2D in leukemia
    • Salih, H.R. et al. Functional expression and release of ligands for the activating immunoreceptor NKG2D in leukemia. Blood 102, 1389-1396 (2003).
    • (2003) Blood , vol.102 , pp. 1389-1396
    • Salih, H.R.1
  • 181
    • 0030890603 scopus 로고    scopus 로고
    • Mouse CD1-specific NK1 T cells: Development, specificity, and function
    • Bendelac, A., Rivera, M.N., Park, S.H. & Roark, J.H. Mouse CD1-specific NK1 T cells: development, specificity, and function. Annu. Rev. Immunol. 15, 535-562 (1997).
    • (1997) Annu. Rev. Immunol. , vol.15 , pp. 535-562
    • Bendelac, A.1    Rivera, M.N.2    Park, S.H.3    Roark, J.H.4
  • 182
    • 0034353121 scopus 로고    scopus 로고
    • Recognition and function of Vα14 NKT cells
    • Taniguchi, M. & Nakayama, T. Recognition and function of Vα14 NKT cells. Semin. Immunol. 12, 543-550 (2000).
    • (2000) Semin. Immunol. , vol.12 , pp. 543-550
    • Taniguchi, M.1    Nakayama, T.2
  • 183
    • 0030826423 scopus 로고    scopus 로고
    • Crystal structure of mouse CD1: An MHC-like fold with a large hydrophobic binding groove
    • Zeng, Z. et al. Crystal structure of mouse CD1: An MHC-like fold with a large hydrophobic binding groove. Science 277, 339-345 (1997).
    • (1997) Science , vol.277 , pp. 339-345
    • Zeng, Z.1
  • 184
    • 0030696696 scopus 로고    scopus 로고
    • CD1d-restricted and TCR-mediated activation of Vα14 NKT cells by glycosylceramides
    • Kawano, T. et al. CD1d-restricted and TCR-mediated activation of Vα14 NKT cells by glycosylceramides. Science 278, 1626-1629 (1997).
    • (1997) Science , vol.278 , pp. 1626-1629
    • Kawano, T.1
  • 185
    • 10044280324 scopus 로고    scopus 로고
    • Lysosomal glycosphingolipid recognition by NKT cells
    • published online 11 November (doi: 10.1126/science.1103440)
    • Zhou, D. et al. Lysosomal glycosphingolipid recognition by NKT cells. Science, published online 11 November 2004 (doi: 10.1126/science.1103440)
    • (2004) Science
    • Zhou, D.1
  • 186
    • 0347776209 scopus 로고    scopus 로고
    • Mechanism of CD1d-restricted natural killer T cell activation during microbial infection
    • Brigl, M., Bry, L., Kent, S.C., Gumperz, J.E. & Brenner, M.B. Mechanism of CD1d-restricted natural killer T cell activation during microbial infection. Nat. Immunol. 4, 1230-1237 (2003).
    • (2003) Nat. Immunol. , vol.4 , pp. 1230-1237
    • Brigl, M.1    Bry, L.2    Kent, S.C.3    Gumperz, J.E.4    Brenner, M.B.5
  • 187
    • 0028209540 scopus 로고
    • Role of NK1.1+ cells in experimental listeriosis. NK1+ cells are early IFN-gamma producers but impair resistance to Listeria monocytogenes infection
    • Teixeira, H.C. & Kaufmann, S.H. Role of NK1.1+ cells in experimental listeriosis. NK1+ cells are early IFN-gamma producers but impair resistance to Listeria monocytogenes infection. J. Immunol. 152, 1873-1882 (1994).
    • (1994) J. Immunol. , vol.152 , pp. 1873-1882
    • Teixeira, H.C.1    Kaufmann, S.H.2
  • 189
    • 0035424543 scopus 로고    scopus 로고
    • NK cells and NKT cells in innate defense against viral infections
    • Biron, C.A. & Brossay, L. NK cells and NKT cells in innate defense against viral infections. Curr. Opin. Immunol. 13, 458-464 (2001).
    • (2001) Curr. Opin. Immunol. , vol.13 , pp. 458-464
    • Biron, C.A.1    Brossay, L.2
  • 191
    • 0141742297 scopus 로고    scopus 로고
    • Some interfaces of dendritic cell biology
    • Steinman, R.M. Some interfaces of dendritic cell biology. APMIS 111, 675-697 (2003).
    • (2003) APMIS , vol.111 , pp. 675-697
    • Steinman, R.M.1
  • 192
    • 0027436739 scopus 로고
    • Saying the 'S' word in public
    • Green, D.R. & Webb, D.R. Saying the 'S' word in public. Immunol. Today 14, 523-525 (1993).
    • (1993) Immunol. Today , vol.14 , pp. 523-525
    • Green, D.R.1    Webb, D.R.2
  • 193
    • 0034084162 scopus 로고    scopus 로고
    • Regulatory T cells in autoimmmunity*
    • Shevach, E.M. Regulatory T cells in autoimmmunity*. Annu. Rev. Immunol. 18, 423-449 (2000).
    • (2000) Annu. Rev. Immunol. , vol.18 , pp. 423-449
    • Shevach, E.M.1
  • 195
    • 0029150110 scopus 로고
    • Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor α-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases
    • Sakaguchi, S., Sakaguchi, N., Asano, M., Itoh, M. & Toda, M. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor α-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J. Immunol. 155, 1151-1164 (1995).
    • (1995) J. Immunol. , vol.155 , pp. 1151-1164
    • Sakaguchi, S.1    Sakaguchi, N.2    Asano, M.3    Itoh, M.4    Toda, M.5
  • 196
    • 0347785480 scopus 로고    scopus 로고
    • Control of regulatory T cell development by the transcription factor Foxp3
    • Hori, S., Nomura, T. & Sakaguchi, S. Control of regulatory T cell development by the transcription factor Foxp3. Science 299, 1057-1061 (2003).
    • (2003) Science , vol.299 , pp. 1057-1061
    • Hori, S.1    Nomura, T.2    Sakaguchi, S.3
  • 200
    • 0041931076 scopus 로고    scopus 로고
    • Foxp3 and natural regulatory T cells: Key to a cell lineage?
    • Ramsdell, F. Foxp3 and natural regulatory T cells: key to a cell lineage? Immunity 19, 165-168 (2003).
    • (2003) Immunity , vol.19 , pp. 165-168
    • Ramsdell, F.1
  • 201
    • 0038434099 scopus 로고    scopus 로고
    • Immune dysregulation, polyendocrinopathy, enteropathy, and X-linked inheritance (IPEX), a syndrome of systemic autoimmunity caused by mutations of FOXP3, a critical regulator of T-cell homeostasis
    • Gambineri, E., Torgerson, T.R. & Ochs, H.D. Immune dysregulation, polyendocrinopathy, enteropathy, and X-linked inheritance (IPEX), a syndrome of systemic autoimmunity caused by mutations of FOXP3, a critical regulator of T-cell homeostasis. Curr. Opin. Rheumatol. 15, 430-435 (2003).
    • (2003) Curr. Opin. Rheumatol. , vol.15 , pp. 430-435
    • Gambineri, E.1    Torgerson, T.R.2    Ochs, H.D.3
  • 202
    • 0035187182 scopus 로고    scopus 로고
    • Suppressor T cells-they're back and critical for regulation of autoimmunity!
    • Chatenoud, L., Salomon, B. & Bluestone, J.A. Suppressor T cells-they're back and critical for regulation of autoimmunity! Immunol. Rev. 182, 149-163 (2001).
    • (2001) Immunol. Rev. , vol.182 , pp. 149-163
    • Chatenoud, L.1    Salomon, B.2    Bluestone, J.A.3
  • 204
    • 0035180065 scopus 로고    scopus 로고
    • + regulatory T cells: Their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance
    • + regulatory T cells: their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance. Immunol. Rev. 182, 18-32 (2001).
    • (2001) Immunol. Rev. , vol.182 , pp. 18-32
    • Sakaguchi, S.1
  • 206
    • 4043102582 scopus 로고    scopus 로고
    • Regulatory cells and infectious agents: Detentes cordiale and contraire
    • Rouse, B.T. & Suvas, S. Regulatory cells and infectious agents: detentes cordiale and contraire. J. Immunol. 173, 2211-2215 (2004).
    • (2004) J. Immunol. , vol.173 , pp. 2211-2215
    • Rouse, B.T.1    Suvas, S.2
  • 209
    • 0037018104 scopus 로고    scopus 로고
    • H2-inducing cytokines
    • H2-inducing cytokines. J. Exp. Med. 195, 603-616 (2002).
    • (2002) J. Exp. Med. , vol.195 , pp. 603-616
    • Barrat, F.J.1
  • 210
    • 0348047537 scopus 로고    scopus 로고
    • The main function of IL-2 is to promote the development of T regulatory cells
    • Malek, T.R. The main function of IL-2 is to promote the development of T regulatory cells. J. Leukoc. Biol. 74, 961-965 (2003).
    • (2003) J. Leukoc. Biol. , vol.74 , pp. 961-965
    • Malek, T.R.1
  • 212
    • 0033985780 scopus 로고    scopus 로고
    • Suppressor effector function of CD4+CD25+ immunoregulatory T cells is antigen nonspecific
    • Thornton, A.M. & Shevach, E.M. Suppressor effector function of CD4+CD25+ immunoregulatory T cells is antigen nonspecific. J. Immunol. 164, 183-190 (2000).
    • (2000) J. Immunol. , vol.164 , pp. 183-190
    • Thornton, A.M.1    Shevach, E.M.2
  • 213
    • 0037243827 scopus 로고    scopus 로고
    • + T(R) cells suppress innate immune pathology through cytokine-dependent mechanisms
    • + T(R) cells suppress innate immune pathology through cytokine-dependent mechanisms. J. Exp. Med. 197, 111-119 (2003).
    • (2003) J. Exp. Med. , vol.197 , pp. 111-119
    • Maloy, K.J.1
  • 214
    • 0035801335 scopus 로고    scopus 로고
    • + regulatory T cells is mediated by cell surface-bound transforming growth factor β
    • + regulatory T cells is mediated by cell surface-bound transforming growth factor β. J. Exp. Med. 194, 629-644 (2001).
    • (2001) J. Exp. Med. , vol.194 , pp. 629-644
    • Nakamura, K.1    Kitani, A.2    Strober, W.3
  • 215
    • 1642577126 scopus 로고    scopus 로고
    • + regulatory T cell activity in both humans and mice
    • + regulatory T cell activity in both humans and mice. J. Immunol. 172, 834-842 (2004).
    • (2004) J. Immunol. , vol.172 , pp. 834-842
    • Nakamura, K.1
  • 216
    • 0037436119 scopus 로고    scopus 로고
    • + T cell-mediated suppression by dendritic cells
    • + T cell-mediated suppression by dendritic cells. Science 299, 1033-1036 (2003).
    • (2003) Science , vol.299 , pp. 1033-1036
    • Pasare, C.1    Medzhitov, R.2
  • 218
    • 0036214017 scopus 로고    scopus 로고
    • The B7 family of ligands and its receptors: New pathways for costimulation and inhibition of immune responses
    • Carreno, B.M. & Collins, M. The B7 family of ligands and its receptors: new pathways for costimulation and inhibition of immune responses. Annu. Rev. Immunol. 20, 29-53 (2002).
    • (2002) Annu. Rev. Immunol. , vol.20 , pp. 29-53
    • Carreno, B.M.1    Collins, M.2
  • 220
    • 0035056017 scopus 로고    scopus 로고
    • CTLA-4-mediated inhibition in regulation of T cell responses: Mechanisms and manipulation in tumor immunotherapy
    • Chambers, C.A., Kuhns, M.S., Egen, J.G. & Allison, J.P. CTLA-4-mediated inhibition in regulation of T cell responses: mechanisms and manipulation in tumor immunotherapy. Annu. Rev. Immunol. 19, 565-594 (2001).
    • (2001) Annu. Rev. Immunol. , vol.19 , pp. 565-594
    • Chambers, C.A.1    Kuhns, M.S.2    Egen, J.G.3    Allison, J.P.4
  • 221
    • 0036172220 scopus 로고    scopus 로고
    • Cytotoxic T lymphocyte antigen-4 accumulation in the immunological synapse is regulated by TCR signal strength
    • Egen, J.G. & Allison, J.P. Cytotoxic T lymphocyte antigen-4 accumulation in the immunological synapse is regulated by TCR signal strength. Immunity 16, 23-35 (2002).
    • (2002) Immunity , vol.16 , pp. 23-35
    • Egen, J.G.1    Allison, J.P.2
  • 222
    • 4444369694 scopus 로고    scopus 로고
    • B7-1 and B7-2 selectively recruit CTLA-4 and CD28 to the immunological synapse
    • Pentcheva-Hoang, T., Egen, J.G., Wojnoonski, K. & Allison, J.P. B7-1 and B7-2 selectively recruit CTLA-4 and CD28 to the immunological synapse. Immunity 21, 401-413 (2004).
    • (2004) Immunity , vol.21 , pp. 401-413
    • Pentcheva-Hoang, T.1    Egen, J.G.2    Wojnoonski, K.3    Allison, J.P.4
  • 223
    • 0035794314 scopus 로고    scopus 로고
    • B7-DC, a new dendritic cell molecule with potent costimulatory properties for T cells
    • Tseng, S.Y. et al. B7-DC, a new dendritic cell molecule with potent costimulatory properties for T cells. J. Exp. Med. 193, 839-846 (2001).
    • (2001) J. Exp. Med. , vol.193 , pp. 839-846
    • Tseng, S.Y.1
  • 224
    • 0033180181 scopus 로고    scopus 로고
    • Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor
    • Nishimura, H., Nose, M., Hiai, H., Minato, N. & Honjo, T. Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor. Immunity 11, 141-151 (1999).
    • (1999) Immunity , vol.11 , pp. 141-151
    • Nishimura, H.1    Nose, M.2    Hiai, H.3    Minato, N.4    Honjo, T.5
  • 225
    • 5844264920 scopus 로고    scopus 로고
    • PD-L2 is a second ligand for PD-1 and inhibits T cell activation
    • Latchman, Y. et al. PD-L2 is a second ligand for PD-1 and inhibits T cell activation. Nat. Immunol. 2, 261-268 (2001).
    • (2001) Nat. Immunol. , vol.2 , pp. 261-268
    • Latchman, Y.1
  • 226
    • 2442585121 scopus 로고    scopus 로고
    • Co-inhibitory molecules of the B7-CD28 family in the control of T-cell immunity
    • Chen, L. Co-inhibitory molecules of the B7-CD28 family in the control of T-cell immunity. Nat. Rev. Immunol. 4, 336-347 (2004).
    • (2004) Nat. Rev. Immunol. , vol.4 , pp. 336-347
    • Chen, L.1
  • 227
    • 0042877332 scopus 로고    scopus 로고
    • Immune regulation by novel costimulatory molecules
    • Dong, C., Nurieva, R.I. & Prasad, D.V. Immune regulation by novel costimulatory molecules. Immunol. Res. 28, 39-48 (2003).
    • (2003) Immunol. Res. , vol.28 , pp. 39-48
    • Dong, C.1    Nurieva, R.I.2    Prasad, D.V.3
  • 228
    • 0033746263 scopus 로고    scopus 로고
    • Cell death control in lymphocytes
    • Newton, K. & Strasser, A. Cell death control in lymphocytes. Adv. Immunol. 76, 179-226 (2000).
    • (2000) Adv. Immunol. , vol.76 , pp. 179-226
    • Newton, K.1    Strasser, A.2
  • 229
    • 0028054017 scopus 로고
    • T-cell apoptosis detected in situ during positive and negative selection in the thymus
    • Surh, C.D. & Sprent, J. T-cell apoptosis detected in situ during positive and negative selection in the thymus. Nature 372, 100-103 (1994).
    • (1994) Nature , vol.372 , pp. 100-103
    • Surh, C.D.1    Sprent, J.2
  • 230
    • 0038725685 scopus 로고    scopus 로고
    • Negative selection-clearing out the bad apples from the T-cell repertoire
    • Palmer, E. Negative selection-clearing out the bad apples from the T-cell repertoire. Nat. Rev. Immunol. 3, 383-391 (2003).
    • (2003) Nat. Rev. Immunol. , vol.3 , pp. 383-391
    • Palmer, E.1
  • 234
    • 0030001674 scopus 로고    scopus 로고
    • Immunological memory and protective immunity: Understanding their relation
    • Ahmed, R. & Gray, D. Immunological memory and protective immunity: understanding their relation. Science 272, 54-60 (1996).
    • (1996) Science , vol.272 , pp. 54-60
    • Ahmed, R.1    Gray, D.2
  • 235
    • 0041381363 scopus 로고    scopus 로고
    • + effector and memory T cell generation
    • + effector and memory T cell generation. Nat. Immunol. 4, 835-842 (2003).
    • (2003) Nat. Immunol. , vol.4 , pp. 835-842
    • Seder, R.A.1    Ahmed, R.2
  • 236
    • 0029025441 scopus 로고
    • Dominant interfering Fas gene mutations impair apoptosis in a human autoimmune lymphoproliferative syndrome
    • Fisher, G.H. et al. Dominant interfering Fas gene mutations impair apoptosis in a human autoimmune lymphoproliferative syndrome. Cell 81, 935-946 (1995).
    • (1995) Cell , vol.81 , pp. 935-946
    • Fisher, G.H.1
  • 237
    • 0034733682 scopus 로고    scopus 로고
    • A domain in TNF receptors that mediates ligand-independent receptor assembly and signaling
    • Chan, F.K. et al. A domain in TNF receptors that mediates ligand-independent receptor assembly and signaling. Science 288, 2351-2354 (2000).
    • (2000) Science , vol.288 , pp. 2351-2354
    • Chan, F.K.1
  • 238
    • 0141609073 scopus 로고    scopus 로고
    • Costimulatory members of the TNFR family: Keys to effective T-cell immunity?
    • Croft, M. Costimulatory members of the TNFR family: keys to effective T-cell immunity? Nat. Rev. Immunol. 3, 609-620 (2003).
    • (2003) Nat. Rev. Immunol. , vol.3 , pp. 609-620
    • Croft, M.1
  • 239
    • 0033554726 scopus 로고    scopus 로고
    • Two subsets of memory T lymphocytes with distinct homing potentials and effector functions
    • Sallusto, F., Lenig, D., Forster, R., Lipp, M. & Lanzavecchia, A. Two subsets of memory T lymphocytes with distinct homing potentials and effector functions. Nature 401, 708-712 (1999).
    • (1999) Nature , vol.401 , pp. 708-712
    • Sallusto, F.1    Lenig, D.2    Forster, R.3    Lipp, M.4    Lanzavecchia, A.5
  • 241
    • 0037456367 scopus 로고    scopus 로고
    • + T lymphocytes
    • + T lymphocytes. Nature 421, 852-856 (2003).
    • (2003) Nature , vol.421 , pp. 852-856
    • Janssen, E.M.1
  • 242
    • 1542724501 scopus 로고    scopus 로고
    • Cutting edge: Long-lived CD8 memory and protective immunity in the absence of CD40 expression on CD8 T cells
    • Sun, J.C. & Sevan, M.J. Cutting edge: long-lived CD8 memory and protective immunity in the absence of CD40 expression on CD8 T cells. J. Immunol. 172, 3385-3389 (2004).
    • (2004) J. Immunol. , vol.172 , pp. 3385-3389
    • Sun, J.C.1    Sevan, M.J.2
  • 243
    • 0037432776 scopus 로고    scopus 로고
    • Defective CD8 T cell memory following acute infection without CD4 T cell help
    • Sun, J.C. & Bevan, M.J. Defective CD8 T cell memory following acute infection without CD4 T cell help. Science 300, 339-342 (2003).
    • (2003) Science , vol.300 , pp. 339-342
    • Sun, J.C.1    Bevan, M.J.2
  • 244
    • 0037432787 scopus 로고    scopus 로고
    • Requirement for CD4 T cell help in generating functional CD8 T cell memory
    • Shedlock, D.J. & Shen, H. Requirement for CD4 T cell help in generating functional CD8 T cell memory. Science 300, 337-339 (2003).
    • (2003) Science , vol.300 , pp. 337-339
    • Shedlock, D.J.1    Shen, H.2
  • 246
    • 0030001675 scopus 로고    scopus 로고
    • Lymphocyte homing and homeostasis
    • Butcher, E.C. & Picker, L.J. Lymphocyte homing and homeostasis. Science 272, 60-66 (1996).
    • (1996) Science , vol.272 , pp. 60-66
    • Butcher, E.C.1    Picker, L.J.2
  • 247
    • 0032797272 scopus 로고    scopus 로고
    • Chemokines and cell migration in secondary lymphoid organs
    • Cyster, J.G. Chemokines and cell migration in secondary lymphoid organs. Science 286, 2098-2102 (1999).
    • (1999) Science , vol.286 , pp. 2098-2102
    • Cyster, J.G.1
  • 248
    • 0034609968 scopus 로고    scopus 로고
    • T-cell function and migration. Two sides of the same coin
    • von Andrian, U.H. & Mackay, C.R. T-cell function and migration. Two sides of the same coin. N. Engl. J. Med. 343, 1020-1034 (2000).
    • (2000) N. Engl. J. Med. , vol.343 , pp. 1020-1034
    • Von Andrian, U.H.1    Mackay, C.R.2
  • 249
    • 0035256994 scopus 로고    scopus 로고
    • Chemokines: Immunology's high impact factors
    • Mackay, C.R. Chemokines: immunology's high impact factors. Nat. Immunol. 2, 95-101 (2001).
    • (2001) Nat. Immunol. , vol.2 , pp. 95-101
    • Mackay, C.R.1
  • 250
    • 11144270580 scopus 로고    scopus 로고
    • Chemokines
    • ed. Paul, W.E. (Lippincott, Williams, and Wilkins, Philadelphia)
    • Murphy, P.M. Chemokines. in Fundamental Immunology (ed. Paul, W.E.) 801-840 (Lippincott, Williams, and Wilkins, Philadelphia, 2003).
    • (2003) Fundamental Immunology , pp. 801-840
    • Murphy, P.M.1
  • 251
    • 0033214348 scopus 로고    scopus 로고
    • CCR7 coordinates the primary immune response by establishing functional microenvironments in secondary lymphoid organs
    • Forster, R. et al. CCR7 coordinates the primary immune response by establishing functional microenvironments in secondary lymphoid organs. Cell 99, 23-33 (1999).
    • (1999) Cell , vol.99 , pp. 23-33
    • Forster, R.1
  • 252
    • 0034083091 scopus 로고    scopus 로고
    • The role of chemokine receptors in primary, effector, and memory immune responses
    • Sallusto, F., Mackay, C.R. & Lanzavecchia, A. The role of chemokine receptors in primary, effector, and memory immune responses. Annu. Rev. Immunol. 18, 593-620 (2000).
    • (2000) Annu. Rev. Immunol. , vol.18 , pp. 593-620
    • Sallusto, F.1    Mackay, C.R.2    Lanzavecchia, A.3
  • 253
    • 0030582773 scopus 로고    scopus 로고
    • A putative chemokine receptor, BLR1, directs B cell migration to defined lymphoid organs and specific anatomic compartments of the spleen
    • Forster, R. et al. A putative chemokine receptor, BLR1, directs B cell migration to defined lymphoid organs and specific anatomic compartments of the spleen. Cell 87, 1037-1047 (1996).
    • (1996) Cell , vol.87 , pp. 1037-1047
    • Forster, R.1
  • 254
    • 0034691531 scopus 로고    scopus 로고
    • A chemokine-driven positive feedback loop organizes lymphoid follicles
    • Ansel, K.M. et al. A chemokine-driven positive feedback loop organizes lymphoid follicles. Nature 406, 309-314 (2000).
    • (2000) Nature , vol.406 , pp. 309-314
    • Ansel, K.M.1
  • 255
    • 17644365138 scopus 로고    scopus 로고
    • Chemokines, sphingosine-1-phosphate, and cell migration in secondary lymphoid organs
    • published online 11 October (doi: 10.1146/annurev.immunol.23.021704. 115628)
    • Cyster, J.G. Chemokines, sphingosine-1-phosphate, and cell migration in secondary lymphoid organs. Annu. Rev. Immunol. published online 11 October 2004 (doi: 10.1146/annurev.immunol.23.021704.115628)
    • (2004) Annu. Rev. Immunol.
    • Cyster, J.G.1
  • 256
    • 0038264036 scopus 로고    scopus 로고
    • Selective imprinting of gut-homing T cells by Peyer's patch dendritic cells
    • Mora, J.R. et al. Selective imprinting of gut-homing T cells by Peyer's patch dendritic cells. Nature 424, 88-93 (2003).
    • (2003) Nature , vol.424 , pp. 88-93
    • Mora, J.R.1
  • 257
    • 0038206648 scopus 로고    scopus 로고
    • Dendritic cells support sequential reprogramming of chemoattractant receptor profiles during naive to effector T cell differentiation
    • Kim, C.H., Nagata, K. & Butcher, E.C. Dendritic cells support sequential reprogramming of chemoattractant receptor profiles during naive to effector T cell differentiation. J. Immunol. 171, 152-158 (2003).
    • (2003) J. Immunol. , vol.171 , pp. 152-158
    • Kim, C.H.1    Nagata, K.2    Butcher, E.C.3
  • 258
    • 5644300399 scopus 로고    scopus 로고
    • Retinoic Acid imprints gut-homing specificity on T cells
    • Iwata, M. et al. Retinoic Acid imprints gut-homing specificity on T cells. Immunity 21, 527-538 (2004).
    • (2004) Immunity , vol.21 , pp. 527-538
    • Iwata, M.1
  • 259
    • 0033012398 scopus 로고    scopus 로고
    • Chemokine receptors as HIV-1 coreceptors: Roles in viral entry, tropism, and disease
    • Berger, E.A., Murphy, P.M. & Farber, J.M. Chemokine receptors as HIV-1 coreceptors: roles in viral entry, tropism, and disease. Annu. Rev. Immunol. 17, 657-700 (1999).
    • (1999) Annu. Rev. Immunol. , vol.17 , pp. 657-700
    • Berger, E.A.1    Murphy, P.M.2    Farber, J.M.3
  • 260
    • 0027372505 scopus 로고
    • A receptor for the malarial parasite Plasmodium vivax: The erythrocyte chemokine receptor
    • Horuk, R. et al. A receptor for the malarial parasite Plasmodium vivax: the erythrocyte chemokine receptor. Science 261, 1182-1184 (1993).
    • (1993) Science , vol.261 , pp. 1182-1184
    • Horuk, R.1
  • 261
    • 0035259780 scopus 로고    scopus 로고
    • Viral exploitation and subversion of the immune system through chemokine mimicry
    • Murphy, P.M. Viral exploitation and subversion of the immune system through chemokine mimicry. Nat. Immunol. 2, 116-122 (2001).
    • (2001) Nat. Immunol. , vol.2 , pp. 116-122
    • Murphy, P.M.1
  • 262
    • 0029743737 scopus 로고    scopus 로고
    • Phenotypic analysis of antigen-specific T lymphocytes
    • Altman, J.D. et al. Phenotypic analysis of antigen-specific T lymphocytes. Science 274, 94-96 (1996).
    • (1996) Science , vol.274 , pp. 94-96
    • Altman, J.D.1
  • 263
    • 0037367634 scopus 로고    scopus 로고
    • Use of HLA class II tetramers in tracking antigen-specific T cells and mapping T-cell epitopes
    • Reijonen, H. & Kwok, W.W. Use of HLA class II tetramers in tracking antigen-specific T cells and mapping T-cell epitopes. Methods 29, 282-288 (2003).
    • (2003) Methods , vol.29 , pp. 282-288
    • Reijonen, H.1    Kwok, W.W.2
  • 264
    • 0042738024 scopus 로고    scopus 로고
    • Direct visualization of antigen-specific T cells using peptide-MHC-class I tetrameric complexes
    • Meidenbauer, N., Hoffmann, T.K. & Donnenberg, A.D. Direct visualization of antigen-specific T cells using peptide-MHC-class I tetrameric complexes. Methods 31, 160-171 (2003).
    • (2003) Methods , vol.31 , pp. 160-171
    • Meidenbauer, N.1    Hoffmann, T.K.2    Donnenberg, A.D.3
  • 265
    • 0032480279 scopus 로고    scopus 로고
    • Three-dimensional segregation of supramolecular activation clusters in T cells
    • Monks, C.R., Freiberg, B.A., Kupfer, H., Sciaky, N. & Kupfer, A. Three-dimensional segregation of supramolecular activation clusters in T cells. Nature 395, 82-86 (1998).
    • (1998) Nature , vol.395 , pp. 82-86
    • Monks, C.R.1    Freiberg, B.A.2    Kupfer, H.3    Sciaky, N.4    Kupfer, A.5
  • 266
    • 0032568580 scopus 로고    scopus 로고
    • Visualizing the dynamics of T cell activation: Intracellular adhesion molecule 1 migrates rapidly to the T cell/B cell interface and acts to sustain calcium levels
    • Wulfing, C., Sjaastad, M.D. & Davis, M.M. Visualizing the dynamics of T cell activation: intracellular adhesion molecule 1 migrates rapidly to the T cell/B cell interface and acts to sustain calcium levels. Proc. Natl. Acad. Sci. USA 95, 6302-6307 (1998).
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 6302-6307
    • Wulfing, C.1    Sjaastad, M.D.2    Davis, M.M.3
  • 267
    • 0033538574 scopus 로고    scopus 로고
    • The immunological synapse: A molecular machine controlling T cell activation
    • Grakoui, A. et al. The immunological synapse: a molecular machine controlling T cell activation. Science 285, 221-227 (1999).
    • (1999) Science , vol.285 , pp. 221-227
    • Grakoui, A.1
  • 268
    • 0035059418 scopus 로고    scopus 로고
    • The immunological synapse
    • Bromley, S.K. et al. The immunological synapse. Annu. Rev. Immunol. 19, 375-396 (2001).
    • (2001) Annu. Rev. Immunol. , vol.19 , pp. 375-396
    • Bromley, S.K.1
  • 269
    • 0742305006 scopus 로고    scopus 로고
    • Imaging immune cell interactions and functions: SMACs and the Immunological Synapse
    • Kupfer, A. & Kupfer, H. Imaging immune cell interactions and functions: SMACs and the Immunological Synapse. Semin. Immunol. 15, 295-300 (2003).
    • (2003) Semin. Immunol. , vol.15 , pp. 295-300
    • Kupfer, A.1    Kupfer, H.2
  • 270
    • 0043268924 scopus 로고    scopus 로고
    • Dynamics of cell surface molecules during T cell recognition
    • Davis, M.M. et al. Dynamics of cell surface molecules during T cell recognition. Annu. Rev. Biochem. 72, 717-742 (2003).
    • (2003) Annu. Rev. Biochem. , vol.72 , pp. 717-742
    • Davis, M.M.1
  • 271
    • 0035282433 scopus 로고    scopus 로고
    • Visualizing the generation of memory CD4 T cells in the whole body
    • Reinhardt, R.L., Khoruts, A., Merica, R., Zell, T. & Jenkins, M.K. Visualizing the generation of memory CD4 T cells in the whole body. Nature 410, 101-105 (2001).
    • (2001) Nature , vol.410 , pp. 101-105
    • Reinhardt, R.L.1    Khoruts, A.2    Merica, R.3    Zell, T.4    Jenkins, M.K.5
  • 272
    • 0037036114 scopus 로고    scopus 로고
    • Dynamic imaging of T cell-dendritic cell interactions in lymph nodes
    • Stoll, S., Delon, J., Brotz, T.M. & Germain, R.N. Dynamic imaging of T cell-dendritic cell interactions in lymph nodes. Science 296, 1873-1876 (2002).
    • (2002) Science , vol.296 , pp. 1873-1876
    • Stoll, S.1    Delon, J.2    Brotz, T.M.3    Germain, R.N.4
  • 273
    • 0036831870 scopus 로고    scopus 로고
    • Two-photon tissue imaging: Seeing the immune system in a fresh light
    • Cahalan, M.D., Parker, I., Wei, S.H. & Miller, M.J. Two-photon tissue imaging: seeing the immune system in a fresh light. Nat. Rev. Immunol. 2, 872-880 (2002).
    • (2002) Nat. Rev. Immunol. , vol.2 , pp. 872-880
    • Cahalan, M.D.1    Parker, I.2    Wei, S.H.3    Miller, M.J.4
  • 274
    • 0037036142 scopus 로고    scopus 로고
    • Two-photon imaging of lymphocyte motility and antigen response in intact lymph node
    • Miller, M.J., Wei, S.H., Parker, I. & Cahalan, M.D. Two-photon imaging of lymphocyte motility and antigen response in intact lymph node. Science 296, 1869-1873 (2002).
    • (2002) Science , vol.296 , pp. 1869-1873
    • Miller, M.J.1    Wei, S.H.2    Parker, I.3    Cahalan, M.D.4
  • 275
    • 0037036140 scopus 로고    scopus 로고
    • Dynamics of thymocyte-stromal cell interactions visualized by two-photon microscopy
    • Bousso, P., Bhakta, N.R., Lewis, R.S. & Robey, E. Dynamics of thymocyte-stromal cell interactions visualized by two-photon microscopy. Science 296, 1876-1880 (2002).
    • (2002) Science , vol.296 , pp. 1876-1880
    • Bousso, P.1    Bhakta, N.R.2    Lewis, R.S.3    Robey, E.4
  • 276
    • 0037501371 scopus 로고    scopus 로고
    • + T cell priming by dendritic cells in intact lymph nodes
    • + T cell priming by dendritic cells in intact lymph nodes. Nat. Immunol. 4, 579-585 (2003).
    • (2003) Nat. Immunol. , vol.4 , pp. 579-585
    • Bousso, P.1    Robey, E.2
  • 277
    • 0347717903 scopus 로고    scopus 로고
    • T-cell priming by dendritic cells in lymph nodes occurs in three distinct phases
    • Mempel, T.R., Henrickson, S.E. & Von Andrian, U.H. T-cell priming by dendritic cells in lymph nodes occurs in three distinct phases. Nature 427, 154-159 (2004).
    • (2004) Nature , vol.427 , pp. 154-159
    • Mempel, T.R.1    Henrickson, S.E.2    Von Andrian, U.H.3
  • 278
    • 0037350545 scopus 로고    scopus 로고
    • Immunotherapy: Past, present and future
    • Waldmann, T.A. Immunotherapy: past, present and future. Nat. Med. 9, 269-277 (2003).
    • (2003) Nat. Med. , vol.9 , pp. 269-277
    • Waldmann, T.A.1
  • 279
    • 0037129435 scopus 로고    scopus 로고
    • Sustained correction of X-linked severe combined immunodeficiency by ex vivo gene therapy
    • Hacein-Bey-Abina, S. et al. Sustained correction of X-linked severe combined immunodeficiency by ex vivo gene therapy. N. Engl. J. Med. 346, 1185-1193 (2002).
    • (2002) N. Engl. J. Med. , vol.346 , pp. 1185-1193
    • Hacein-Bey-Abina, S.1
  • 280
    • 0142084745 scopus 로고    scopus 로고
    • LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1
    • Hacein-Bey-Abina, S. et al. LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1. Science 302, 415-419 (2003).
    • (2003) Science , vol.302 , pp. 415-419
    • Hacein-Bey-Abina, S.1
  • 281
    • 1942435994 scopus 로고    scopus 로고
    • Successes and risks of gene therapy in primary immunodeficiencies
    • quiz 604
    • Chinen, J. & Puck, J.M. Successes and risks of gene therapy in primary immunodeficiencies. J. Allergy. Clin. Immunol. 113, 595-603; quiz 604 (2004).
    • (2004) J. Allergy. Clin. Immunol. , vol.113 , pp. 595-603
    • Chinen, J.1    Puck, J.M.2
  • 282
    • 4444243096 scopus 로고    scopus 로고
    • Tumor-specific shared antigenic peptides recognized by human T cells
    • Van Der Bruggen, P. et al. Tumor-specific shared antigenic peptides recognized by human T cells. Immunol. Rev. 188, 51-64 (2002).
    • (2002) Immunol. Rev. , vol.188 , pp. 51-64
    • Van Der Bruggen, P.1
  • 283
    • 0042470540 scopus 로고    scopus 로고
    • Does the immune system see tumors as foreign or self?
    • Pardoll, D. Does the immune system see tumors as foreign or self? Annu. Rev. Immunol. 21, 807-839 (2003).
    • (2003) Annu. Rev. Immunol. , vol.21 , pp. 807-839
    • Pardoll, D.1
  • 284
    • 1842430906 scopus 로고    scopus 로고
    • Shedding light on immunotherapy for cancer
    • Rosenberg, S.A. Shedding light on immunotherapy for cancer. N. Engl. J. Med. 350, 1461-1463 (2004).
    • (2004) N. Engl. J. Med. , vol.350 , pp. 1461-1463
    • Rosenberg, S.A.1
  • 285
    • 1642497640 scopus 로고    scopus 로고
    • + regulatory T cells and their ligands: Implications for immunotherapy
    • + regulatory T cells and their ligands: implications for immunotherapy. Immunity 20, 107-118 (2004).
    • (2004) Immunity , vol.20 , pp. 107-118
    • Wang, H.Y.1
  • 286
    • 0036301503 scopus 로고    scopus 로고
    • CTLA-4: New insights into its biological function and use in tumor immunotherapy
    • Egen, J.G., Kuhns, M.S. & Allison, J.P. CTLA-4: new insights into its biological function and use in tumor immunotherapy. Nat. Immunol. 3, 611-618 (2002).
    • (2002) Nat. Immunol. , vol.3 , pp. 611-618
    • Egen, J.G.1    Kuhns, M.S.2    Allison, J.P.3
  • 287
    • 0344341626 scopus 로고    scopus 로고
    • Biologic activity of cytotoxic T lymphocyte-associated antigen 4 antibody blockade in previously vaccinated metastatic melanoma and ovarian carcinoma patients
    • Hodi, F.S. et al. Biologic activity of cytotoxic T lymphocyte-associated antigen 4 antibody blockade in previously vaccinated metastatic melanoma and ovarian carcinoma patients. Proc. Natl. Acad. Sci. USA 100, 4712-4717 (2003).
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 4712-4717
    • Hodi, F.S.1
  • 288
    • 0038153907 scopus 로고    scopus 로고
    • Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma
    • Phan, G.Q. et al. Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma. Proc. Natl. Acad. Sci. USA 100, 8372-8377 (2003).
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 8372-8377
    • Phan, G.Q.1
  • 290
    • 0035854450 scopus 로고    scopus 로고
    • The art of the probable: System control in the adaptive immune system
    • Germain, R.N. The art of the probable: system control in the adaptive immune system. Science 293, 240-245 (2001).
    • (2001) Science , vol.293 , pp. 240-245
    • Germain, R.N.1
  • 291
    • 0034280834 scopus 로고    scopus 로고
    • A cellular calculus for signal integration by T cells
    • Gett, A.V. & Hodgkin, P.D. A cellular calculus for signal integration by T cells. Nat. Immunol. 1, 239-244 (2000).
    • (2000) Nat. Immunol. , vol.1 , pp. 239-244
    • Gett, A.V.1    Hodgkin, P.D.2
  • 292
    • 19544367597 scopus 로고    scopus 로고
    • End of the interlude?
    • Brenner, S. End of the interlude? Nat. Biotechnol. 22, 1191 (2004).
    • (2004) Nat. Biotechnol. , vol.22 , pp. 1191
    • Brenner, S.1
  • 293
    • 2342496710 scopus 로고    scopus 로고
    • Instruction of distinct CD4 T helper cell fates by different notch ligands on antigen-presenting cells
    • Amsen, D. et al. Instruction of distinct CD4 T helper cell fates by different notch ligands on antigen-presenting cells. Cell 117, 515-526 (2004).
    • (2004) Cell , vol.117 , pp. 515-526
    • Amsen, D.1
  • 294
    • 0142157141 scopus 로고    scopus 로고
    • + T cells
    • + T cells. Immunity 19, 549-559 (2003).
    • (2003) Immunity , vol.19 , pp. 549-559
    • Maekawa, Y.1
  • 295
    • 3142724031 scopus 로고    scopus 로고
    • Toll-like receptor signalling
    • Akira, S. & Takeda, K. Toll-like receptor signalling. Nat. Rev. Immunol. 4, 499-511 (2004).
    • (2004) Nat. Rev. Immunol. , vol.4 , pp. 499-511
    • Akira, S.1    Takeda, K.2
  • 296
    • 1542615649 scopus 로고    scopus 로고
    • Inhibitory NK-cell receptors on T cells: Witness of the past, actors of the future
    • Vivier, E. & Anfossi, N. Inhibitory NK-cell receptors on T cells: witness of the past, actors of the future. Nat. Rev. Immunol. 4, 190-198 (2004).
    • (2004) Nat. Rev. Immunol. , vol.4 , pp. 190-198
    • Vivier, E.1    Anfossi, N.2
  • 297
    • 3042569008 scopus 로고    scopus 로고
    • Learning how to discriminate between friends and enemies, a lesson from Natural Killer cells
    • Bottino, C., Moretta, L., Pende, D., Vitale, M. & Moretta, A. Learning how to discriminate between friends and enemies, a lesson from Natural Killer cells. Mol. Immunol. 41, 569-575 (2004).
    • (2004) Mol. Immunol. , vol.41 , pp. 569-575
    • Bottino, C.1    Moretta, L.2    Pende, D.3    Vitale, M.4    Moretta, A.5
  • 298
    • 5644302161 scopus 로고    scopus 로고
    • Human T regulatory cells can use the perforin pathway to cause autologous target cell death
    • Grossman, W.J. et al. Human T regulatory cells can use the perforin pathway to cause autologous target cell death. Immunity 21, 589-601 (2004).
    • (2004) Immunity , vol.21 , pp. 589-601
    • Grossman, W.J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.