Experience of combination treatment of toenail onychomycosis with oral itraconazole and topical 5% amorolfine nail lacquer

Korean Journal of Medical Mycology

Volumn 9, Issue 3, 2004, Pages 159-165

  Yang, Hyun Yoon ^a   Ji, Young An ^a   Byung, In Ro ^a  

^a Chung Ang University College of Medicine   (South Korea)

Author keywords

Combination treatment; Onychomycosis; Oral itraconazole; Topical amorolfine nail lacquer

Indexed keywords

AMOROLFINE; ITRACONAZOLE;

ARTICLE; CAMERA; CANDIDA; DIABETES MELLITUS; DIAGNOSTIC PROCEDURE; DISEASE ASSOCIATION; DISEASE CLASSIFICATION; DRUG EFFICACY; FEMALE; FUNGAL CELL CULTURE; FUNGAL STRAIN; HUMAN; MAJOR CLINICAL STUDY; MALE; NAIL; ONYCHOMYCOSIS; STATISTICAL SIGNIFICANCE;

CANDIDA; FUNGI;

EID: 11144326764     PISSN: 12264709     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

1. Hay RT, Clayton YM, Griffiths WAD, Dowd PM. A comparative double blind study of ketoconazole and griscofulvin in dermatophytosis. Br J Dermatol 1985; 112: 691-696
2. Roverts DT. Oral therapeutic agents in fungal nail disease. J Am Acad Dermatol 1994; 31(suppl): 798 -811
3. Gupta AK, Sauder DN, Shear NH. Antifungal agents: An overview. Part II. J Am Acad Dermatol 1994; 40: 911-933
4. Hay RJ. The future of onychomycosis therapy may involve a combination of approaches. Br J Dermatol 2001; 145 (Suppl. 60): 3-8
5. Gupta AK, Konnikov N, Lynde CW. Sequential pulse therapy with itraconazole and terbinafine to treat onychomycosis of the fingernails. J Dermatol Treat 2000; 11: 151-154
6. Scher RK. Onychomycosis is more than a cosmetic problem. Br J Dermatol 1994; 130 (Suppl. 43): 15
7. Polak A. Preclinical data and mode of action of amorolfine. Dermatology 1992; 184 (supp 1): 3-7
8. Pittrof F, Gerhards J, Erni W, Klecak G. Loceryl nail lacquer-realization of a new galenical approach to onychomycoses therapy. Clin Exp Dermatol 1992; 17 (Suppl 6): 26-28
9. Zaug M, Hergstraesser M. Amorolfine in the treatment of onychomycosis and dermatomycoses (an overview). Clin Exp Dermatol 1992; 17 (Suppl 1): 61-67
10. Franz T. Absorption of amorolfine through human nail. Dermatology 1992; 184 (Suppl 1): 18-20
11. Polak A. Kinetics of amorolfine in human nails. Mycoses 993; 36: 101-103
12. Scher RK, Baran R. Onychomycosis in clinical practice: factors contributing to recurrence. Br J Dermatol 2003; 149 (Suppl 65): 5-9
13. Clayton YM. Relevance of broad-spectrum and fungicidal activity of antifungals in the treatment of dermatomycoses. Br J Dermatol 1994; 130 (Supp 4): 7 -8
14. Epstein E. How often does oral treatment of toenail onychomycosis produce a disease-free nail? Arch Dermatol 1998; 134: 1551-1554
15. Lecha M. Amorolfine and itraconazole combination for severe toenail onychomycosis: result of an open randomized trial in Spain. Br J Dermatol 2001; 145 (Suppl 60): 21-26