Regulation of cellulase synthesis in batch and continuous cultures of Clostridium thermocellum

Journal of Bacteriology

Volumn 187, Issue 1, 2005, Pages 99-106

  Zhang, Yi Heng Percival ^a   Lynd, Lee R ^a,b  

^a DARTMOUTH COLLEGE   (United States)

^b Dartmouth College   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON; CELLOBIOSE; MICROCRYSTALLINE CELLULOSE;

AMINO ACID SEQUENCE; ARTICLE; BACTERIAL GENOME; BACTERIAL GROWTH; BACTERIUM CULTURE; CLOSTRIDIUM THERMOCELLUM; CONCENTRATION (PARAMETERS); CONTINUOUS CULTURE; DILUTION; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME SUBSTRATE; ENZYME SYNTHESIS; HYDROLYSIS; NONHUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM;

CARBON; CELLOBIOSE; CELLULASE; CELLULOSE; CLOSTRIDIUM THERMOCELLUM; ENZYME-LINKED IMMUNOSORBENT ASSAY; RESPONSE ELEMENTS;

BACTERIA (MICROORGANISMS); CLOSTRIDIUM; CLOSTRIDIUM THERMOCELLUM; POSIBACTERIA;

EID: 11144320832     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/JB.187.1.99-106.2005     Document Type: Article

References (57)

1. Bayer, E. A., R. Kenig, and R. L. Lamed. 1983. Adherence of Clostridium thermocellum to cellulose. J. Bacteriol. 156:818-827.
2. Bayer, E. A., E. Setter, and R. L. Lamed. 1985. Organization and distribution of the cellulosome in Clostridium thermocellum. J. Bacteriol. 163:552-559.
3. Bhat, S., P. W. Goodenough, E. Owen, and M. K. Bhat. 1993. Cellobiose: a true inducer of cellulosome in different strains of Clostridium thermocellum. FEMS Microbiol. Lett. 111:73-78.
4. Chauvaux, S. 1996. CcpA and HPr(ser-P): mediators of catabolite repression in Bacillus subtilis. Res. Microbiol. 147:518-522.
5. Davison, S. P., J. D. Santangelo, S. J. Reid, and D. R. Woods. 1995. A Clostridium acetobutylicum regulator gene (regA) affecting amylase production in Bacillus subtilis. Microbiology 141:989-996.
6. Desvaux, M., E. Guedon, and H. Petitdemange. 2001. Kinetics of metabolism of cellulose degradation at high substrate concentrations in steady-state continuous culture of Clostridium cellulolyticum on a chemically defined medium. Appl. Environ. Microbiol. 67:3827-3845.
7. Desvaux, M., E. Guedon, and H. Petitdemange. 2001. Carbon flux distribution and kinetics of cellulose fermentation in steady-state continuous cultures of Clostridium cellulolyticum on a chemically defined medium. J. Bacteriol. 183:119-130.
8. Dror, T. W., E. Morag, A. Rolider, E. A. Bayer, R. Lamed, and Y. Shoham. 2003. Regulation of the cellulosomal CelS (cel48A) gene of Clostridium thermocellum is growth rate dependent. J. Bacteriol. 185:3042-3048.
9. Dror, T. W., A. Rolider, E. A. Bayer, R. Lamed, and Y. Shoham. 2003. Regulation of expression of scaffoldin-related genes in Clostridium thermocellum. J. Bacteriol. 185:5109-5116.
10. El-Gogary, S., A. Leite, O. Crivellaro, D. E. Eveleigh, and H. El-Dorry. 1989. Mechanism by which cellulose triggers cellobiohydrolase I gene expression in Trichoderma reesei. Proc. Natl. Acad. Sci. USA 86:6138-6141.
11. Esterbauer, H., W. Steiner, I. Labudova, A. Hermann, and M. Hayn. 1991. Production of Trichoderma cellulase in laboratory and pilot scale. Biores. Technol. 36:51-65.
12. Garcia-Martinez, D. V., A. Shinomyo, A. Madia, and A. L. Demain. 1980. Studies on cellulase production by Clostridium thermocellum. Eur. J. Appl. Microbiol. Biotechnol. 9:189-197.
13. Glanemann, C., A. Loos, N. Gorret, L. B. Willis, X. M. O'Brien, P. A. Lessard, and A. J. Sinskey. 2003. Disparity between changes in mRNA abundance and enzyme activity in Corynebacterium glutamicum: implications for DNA microarray analysis. Appl. Microbiol. Biotechnol. 61:61-68.
14. Goda, S. K., O. Eisa, M. Akhter, and N. P. Minton. 1998. Molecular analysis of the malR gene of Clostridium butyricum NCIMB 7423, a member of the LacI-GalR family of repressor proteins. FEMS Microbiol Lett. 165:193-200.
15. Gosseringer, R., E. Kuster, A. Galinier, J. Deutscher, and W. Hillen. 1997. Cooperative and non-cooperative DNA binding modes of catabolite control protein CcpA from Bacillus megaterium result from sensing two different signals. J. Mol. Biol. 266:665-676.
16. Greenberg, N. M., R. A. J. Warren, D. G. Kilburn, and R. C. Miller, Jr. 1987. Regulation, initiation, and termination of the cenA and cex transcripts of Cellulomonas fimi. J. Bacteriol. 169:646-653.
17. Greenberg, N. M., R. A. J. Warren, D. G. Kilburn, and R. C. Miller Jr. 1987. Regulation and initiation of cenB transcripts of Cellulomonas fimi. J. Bacteriol. 169:4674-4677.
18. Gygi, S. P., Y. Rochon, B. R. Franza, and R. Aebersold. 1999. Correlation between protein and mRNA abundance in yeast. Mol. Cell. Biol. 19:1720-1730.
19. Halliwell, G., T. M. Phillips, and N. Halliwell. 1995. Microcrystalline forms of cellulose as substrates for strains of Clostridium thermocellum and cellulase formation. Proc. Biochem. 30:243-250.
20. Han, S. O., H. Yukawa, M. Inui, and R. H. Doi. 2003. Transcription of Clostridium cellulovorans cellulosomal cellulase and hemicellulase genes. J. Bacteriol. 185:2520-2527.
21. Hayn, M., and H. Esterbauer. 1985. Separation and partial characterization of Trichoderma reesei cellulase by fast chromatofocusing. J. Chromatogr. 329:379-387.
22. Hueck, C. J., W. Hillen, and M. H. Saier, Jr. 1994. Analysis of a cis-active sequence mediating catabolite repression in Gram-positive bacteria. Res. Microbiol. 145:503-518.
23. Ilmen, M., A. Saloheimo, M.-L. Onnela, and M. E. Penttila. 1997. Regulation of cellulase gene expression in the filamentous fungus Trichoderma reesei. Appl. Environ. Microbiol. 63:1298-1306.
24. Isaacs, F. J., D. J. Dwyer, C. Ding, D. D. Pervouchine, C. R. Cantor, and J. J. Collins. 2004. Engineered riboregulators enable post-transcriptional control of gene expression. Nat. Biotechnol. 22:841-847.
25. Johnson, E. A., F. Bouchot, and A. L. Demain. 1985. Regulation of cellulase formation in Clostridium thermocellum. J. Gen. Microbiol. 131:2303-2308.
26. Johnson, E. A., M. Sakajoh, G. Halliwell, A. Madia, and A. L. Demain. 1982. Saccharification of complex cellulosic substrates by the cellulase system from Clostridium thermocellum. Appl. Environ. Microbiol. 43:1125-1132.
27. Kosugi, A., K. Murashima, and R. H. Doi. 2001. Characterization of xylanolytic enzymes in Clostridium cellulovorans: expression of xylanase activity dependent on growth substrates. J. Bacteriol. 183:7037-7043.
28. Kruus, K., W. K. Wang, J. Ching, and J. H. D. Wu. 1995. Exoglucanase activities of the recombinant Clostridium thermocellum CelS, a major cellulosome component. J. Bacteriol. 177:1641-1644.
29. Lamed, R., E. Setter, and E. A. Bayer. 1983. Characterization of a cellulose-binding, cellulase-containing complex in Clostridium thermocellum. J. Bacteriol. 156:828-836.
30. Lin, E., and D. B. Wilson. 1987. Regulation of β-1,4,-endoglucanase synthesis in Thermomospora fusca. Appl. Environ. Microbiol. 53:1352-1357.
31. Lin, E., and D. B. Wilson. 1988. Transcription of the celE gene in Thermomonospora fusca. J. Bacteriol. 170:3838-3842.
32. Lou, J., K. A. Dawson, and H. J. Strobel. 1997. Cellobiose and cellodextrin metabolism by the ruminal bacterium Ruminococcus albus. Curr. Microbiol. 35:221-227.
33. Lynd, L. R., H. E. Grethlein, and R. H. Wolkin. 1989. Fermentation of cellulosic substrates in batch and continuous cultures by Clostridium thermocellum. Appl. Environ. Microbiol. 55:3131-3139.
34. Lynd, L. R., P. J. Weimer, W. H. van Zyl, and I. S. Pretorius. 2002. Microbial cellulose utilization: fundamentals and biotechnology. Microbiol. Mol. Biol. Rev. 66:506-577.
35. Lynd, L. R., and Y. H. Zhang. 2002. Quantitative determination of cellulase concentration as distinct from cell concentration in studies of microbial cellulose utilization: analytical framework and methodological approach. Biotechnol. Bioeng. 77:467-475.
36. Mach, R. L., J. Strauss, S. Zeilinger, M. Schindler, and C. P. Kubicek. 1996. Carbon catabolite repression of xylanase I (xyn1) gene expression in Trichoderma reesei. Mol. Microbiol. 21:1273-1281.
37. Margolles-Clark, E., M. Ilmen, and M. Penttila. 1997. Expression patterns often hemicellulase genes of the filamentous fungus Trichoderma reesei on various carbon sources. J. Biotechnol. 57:167-179.
38. Mayer, F., M. P. Coughlan, Y. Mori, and L. G. Ljungdahl. 1987. Macromolecular organization of the cellulolytic enzyme complex of Clostridium thermocellum as revealed by electron microscopy. Appl. Environ. Microbiol. 53:2785-2792.
39. Messner, R., and C. P. Kubicek. 1991. Carbon source control of cellobiohydrolase I and II formation by Trichoderma reesei. Appl. Environ. Microbiol. 57:630-635.
40. Mishra, S., P. Beguin, and J.-P. Aubert. 1991. Transcription of Clostridium thermocellum endoglucanases genes celF and celD. J. Bacteriol. 173:80-85.
41. Moreno, M. S., B. L. Schneider, R. R. Maile, W. Weyler, and M. H. Saier, Jr. 2001. Catabolite repression mediated by the CcpA protein in Bacillus subtilis: novel modes of regulation revealed by whole-genome analysis. Mol. Microbiol. 39:1366-1381.
42. Ni, X., and J. Westpheling. 1997. Direct repeat sequences in the Streptomyces chitinase-63 promoter direct both glucose repression and chitin induction. Proc. Natl. Acad. Sci. USA 94:13116-13121.
43. Nogueira, T., and M. Springer. 2000. Post-transcriptional control by global regulators of gene expression in bacteria. Curr. Opin. Microbiol. 3:154-158.
44. Novick, A., and L. Szilard. 1950. Description of the chemostat. Science 112:715-716.
45. Saier, M. H., Jr., S. Chauvaux, G. M. Cook, J. Deutscher, I. T. Paulsen, J. Reizer, and J.-J. Ye. 1996. Catabolite repression and inducer control in Gram-positive bacteria. Microbiology 142:217-230.
46. Schwarz, W. H. 2001. The cellulosome and cellulose degradation by anaerobic bacteria. Appl. Microbiol. Biotechnol. 56:634-649.
47. Shafer, M. L., and K. W. King. 1965. Utilization of cellulose oligosaccharides of Cellvibrio gilvus. J. Bacteriol. 89:113-116.
48. Shoham, Y., R. Lamed, and E. A. Bayer. 1999. The cellulosome concept as an efficient microbial strategy for the degradation of insoluble polysaccharides. Trends Biotechnol. 7:275-281.
49. Spiridonov, N. A., and D. B. Wilson. 1998. Regulation of biosynthesis of individual cellulases in Thermomonospora fusca. J. Bacteriol. 180:3529-3532.
50. Spiridonov, N. A., and D. B. Wilson. 1999. Characterization and cloning of celR, a transcriptional regulator of cellulase genes from Thermomonospora fusca. J. Biol. Chem. 274:13127-13132.
51. Spiridonov, N. A., and D. B. Wilson. 2000. A celR mutation affecting transcription of cellulase genes in Thermobifida fusca. J. Bacteriol. 182:252-255.
52. Strobel, H. J. 1995. Growth of the thermophilic bacterium Clostridium thermocellum in continuous cultures. Curr. Microbiol. 31:210-214.
53. Thurston, B., K. A. Dawson, and H. J. Strobel. 1993. Cellobiose versus glucose metabolism by the ruminal bacterium Ruminococcus albus. Appl. Environ. Microbiol. 59:2631-2637.
54. Warner, J. B., and J. S. Lolkema. 2003. Ccp-dependent carbon catabolite repression in bacteria. Microbiol. Mol. Biol. Rev. 67:475-490.
55. Woods, D. R., and S. J. Reid. 1995. Regulation of nitrogen metabolism, starch utilization and the β-hbd-adh1 gene cluster in Clostridium acetobutylicum. FEMS Microbiol. Rev. 17:299-306.
56. Zhang, Y. H., and L. R. Lynd. 2003. Quantification of cell and cellulase mass concentrations during anaerobic cellulose fermentation: development of an ELISA-based method with application to Clostridium thermocellum batch cultures. Anal. Chem. 75:219-227.
57. Zhang, Y.-H. P., and L. R. Lynd. 2004. Kinetics and relative importance of phosphorolytic and hydrolytic cleavage of cellodextrins and cellobiose in cell extracts of Clostridium thermocellum. Appl. Environ. Microbiol. 70:1563-1569.