Molecular mechanisms for activation of voltage-independent Ca2+ channels by endothelin-1/endothelin-A receptors

Journal of Cardiovascular Pharmacology

Volumn 44, Issue SUPPL. 1, 2004, Pages

  Kawanabe, Yoshifumi ^a,b   Okamoto, Yasuo ^a   Hashimoto, Nobuo ^a   Masaki, Tomoh ^a  

^a KYOTO UNIVERSITY   (Japan)

^b TAKATSUKI RED CROSS HOSPITAL   (Japan)

Author keywords

Calcium channel; Endothelin; G protein

Indexed keywords

1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; 2 MORPHOLINO 8 PHENYLCHROMONE; CYSTEINE; ENDOTHELIN 1; ENDOTHELIN A RECEPTOR; ENZYME INHIBITOR; GUANINE NUCLEOTIDE BINDING PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOLIPASE C; SERINE; VOLTAGE GATED CALCIUM CHANNEL;

AMINO ACID SUBSTITUTION; ANIMAL CELL; CARBOXY TERMINAL SEQUENCE; CONFERENCE PAPER; CONTROLLED STUDY; MICROINJECTION; MUTANT; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; CALCIUM CHANNELS; CALCIUM SIGNALING; CHO CELLS; CHROMONES; CRICETINAE; CRICETULUS; ENDOTHELIN-1; ENZYME INHIBITORS; ESTRENES; GTP-BINDING PROTEIN ALPHA SUBUNITS, G12-G13; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; GTP-BINDING PROTEIN ALPHA SUBUNITS, GS; MORPHOLINES; MUTATION; PYRROLIDINONES; RECEPTOR, ENDOTHELIN A; TRANSFECTION; TYPE C PHOSPHOLIPASES;

EID: 11144318785     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.fjc.0000166252.66486.06     Document Type: Conference Paper

References (11)

1. Yanagisawa M, Kurihara H, Kimura S, et al. A novel potent vasoconstrictor peptide produced by vascular endothelial cells. Nature. 1988;332:411-415.
2. 2+ channels involved in endothelin-induced mitogenic response in carotid artery vascular smooth muscle cells. Am J Physiol Cell Physiol. 2002;C330-C337.
3. 2+ channels involved in endothelin-1-induced contraction of rabbit basilar artery. J Cardiovascular Pharmacol. 2002;40:438-447.
4. Arai H, Hori S, Aramori I, et al. Cloning and expression of a cDNA encoding an endothelin receptor. Nature. 1990;348:730-732.
5. Sakurai T, Yanagisawa M, Takuwa Y, et al. Cloning of cDNA encoding a non-isopeptide-selective subtype of the endothelin receptor. Nature. 1990;348:732-735.
6. 2+ channels activated by endothelin-1 in CHO cells expressing endothelin-A or endothelin-B receptors. Am J Physiol Cell Physiol. 2001;281:C1676-C1685.
7. A receptor. Mol Pharmacol. 2002;61:277-284.
8. 2--channel current in vascular smooth muscle cells is inhibited by lavendustin-A and LY-294002. Pflügers Arch. 1999;437:317-323.
9. 2+ signaling. J Biol Chem. 2000;275:16242-16250.
10. Zhang XF, Iwamuro Y, Enoki T, et al. Pharmacological characterization of Ca entry channels in endothelin-1-induced contraction of rat aorta using LOE 908 and SK&F 96365. Br J Pharmacol. 1999;127:1388-1398.
11. Kusch A, Tkachuk S, Haller H, et al. Ukokinase stimulates human vascular smooth muscle cell migration via a phosphatidylinositol 3-kinase-Tyk2 interaction. J Biol Chem. 2000;275:39466-39473.