Stereoselective TiCl4-promoted nucleophilic substitution at C-2 of (45,5S)-2-alkyl-4-methyl-5-trifluoromethyl-1,3-dioxolanes

Synthesis

Volumn , Issue 18, 2004, Pages 3005-3010

  Morelli, Carlo F ^a   Durì, Lavinia ^a   Saladino, Alberto ^a   Speranza, Giovanna ^a   Manitto, Paolo ^a  

^a UNIVERSITY OF MILAN   (Italy)

Author keywords

Acetals; Allylations; Chiral auxiliary; Ring opening; Stereoselectivity

Indexed keywords

ALCOHOLS; ORGANOMETALLICS; STEREOCHEMISTRY; SUBSTITUTION REACTIONS;

REGIOSELECTIVITY; SECONDARY ALCOHOLS;

TITANIUM COMPOUNDS;

1 PHENYLHEX 5 EN 3 OL; 1,1,1 TRIFLUORO 3 (1 HEPTYLBUT 3 EN 1 YL)BUTAN 2 OL; 1,1,1 TRIFLUORO 3 (2 PHENYLETHOXY)BUTAN 2 OL; 1,1,1 TRIFLUORO 3 (OCTYLOXY)BUTAN 2 OL; 1,1,1 TRIFLUORO 3 [(2 PHENYLPROP 2 EN 1 YL)OXY]BUTAN 2 OL; 1,1,1 TRIFLUORO 3 [(3 PHENYLPROPYL)OXY]BUTAN 2 OL; 1,1,1 TRIFLUORO 3 [[1 (2 PHENYLETHYL)BUT 3 EN 1 YL]OXY]BUTAN 2 OL; 1,3 DIOXOLANE DERIVATIVE; 2 [[1 (2 PHENYLETHYL)BUT 3 EN 1 YL]OXY]PROPANOIC ACID; 2 BENZYL 4 METHYL 5 (TRIFLUOROMETHYL) 1,3 DIOXOLANE; 2 CYCLOHEXYL 4 METHYL 5 (TRIFLUOROMETHYL) 1,3 DIOXOLANE; 2 HEPTYL 4 METHYL 5 (TRIFLUOROMETHYL) 1,3 DIOXOLANE; 3 (CYCLOHEXYLMETHOXY) 1,1,1 TRIFLUOROBUTAN 2 OL; 3 [(1 CYCLOHEXYLBUT 3 EN 1 YL)OXY] 1,1,1 TRIFLUOROBUTAN 2 OL; 4 METHYL 2 (2 PHENETHYL) 5 (TRIFLUOROMETHYL) 1,3 DIOXOLANE; 4 METHYL 2 (2 STYRYL) 5 (TRIFLUOROMETHYL) 1,3 DIOXOLANE; 4,4,4 TRIFLUORO 3 (OCTYLOXY)BUTAN 2 OL; [[[2 (OCTYLOXY) 1 (TRIFLUOROMETHYL)PROPYL]OXY]METHYL]BENZENE; ACETAL; ALCOHOL; TITANIUM TETRACHLORIDE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL BOND; CHEMICAL STRUCTURE; CHIRALITY; ENANTIOMER; RING OPENING; STEREOCHEMISTRY;

EID: 11144312353     PISSN: 00397881     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2004-834884     Document Type: Article

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