Kinetics of LFA-1 binding to ICAM-1 studied in a cell-free system

Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings

Volumn 26 VII, Issue , 2004, Pages 4974-4977

  Sarantos, M R ^a   Lum, A F H ^a   Staunton, D E ^b   Simon, S I ^a  

^a University of California Davis   (United States)

^b ELI LILLY AND COMPANY   (United States)

Author keywords

Inflammation; Integrin conformation; Neutrophil adhesion

Indexed keywords

BINDING ENERGY; CONFORMATIONS; DIMERS; FLAMMABILITY; POSITIVE IONS; REACTION KINETICS;

HETERODIMERS; INFLAMMATION; INTEGRIN CONFORMATION; NEUTROPHIL ADHESION;

CELLS;

EID: 11144297750     PISSN: 05891019     EISSN: None     Source Type: Conference Proceeding    
DOI: None     Document Type: Conference Paper

References (6)

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2. J. R. Woska, Jr., M. M. Morelock, D. D. Jeanfavre, and B. J. Borraann, "Characterization of molecular interactions between intercellular adhesion molecule-1 and leukocyte function-associated antigen-1," J Immunol, vol. 156, pp. 4680-5, 1996.
3. J. Miller, R. Knorr, M. Ferrone, R. Houdei, C. P. Carron, and M. L. Dustin, "Intercellular adhesion molecule-1 dimerization and its consequences for adhesion mediated by lymphocyte function associated-1," J Exp Med, Vol. 182, pp. 1231-41, 1995.
4. C. D. Jun, C. V. Carman, S. D. Redick, M. Shimaoka, H. P. Erickson, and T. A. Springer, "Ultrastructure and function of dimeric, soluble intercellular adhesion molecule-1 (ICAM-1)," J Biol Chem, vol. 276, pp. 29019-27, 2001.
5. A. F. Lum, C. E. Green, G. R. Lee, D. E. Staunton, and S. I. Simon, "Dynamic regulation of LFA-1 activation and neutrophil arrest on intercellular adhesion molecule 1 (ICAM-1) in shear flow," J Biol Chem, vol. 277, pp. 20660-70, 2002.
6. Y. van Kooyk and C. G. Figdor, "Avidity regulation of integrins: the driving force in leukocyte adhesion," Curr Opin Cell Biol, vol. 12, pp. 542-7, 2000.