Effect of increasing doses of magnesium in experimental pulmonary hypertension after acute pulmonary embolism

Intensive Care Medicine

Volumn 30, Issue 11, 2004, Pages 2102-2109

  Haas, Nikolaus A ^a,b   Kemke, Jan ^a   Schulze Neick, Ingram ^a   Lange, Peter E ^a  

^a DEUTSCHES HERZZENTRUM BERLIN   (Germany)

^b THE PRINCE CHARLES HOSPITAL   (Australia)

Author keywords

Animal experiment; Cardiac output; Magnesium; Pulmonary circulation; Pulmonary embolism; Pulmonary hypertension

Indexed keywords

MAGNESIUM;

ACUTE DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERY CATHETERIZATION; ARTICLE; CENTRAL VENOUS PRESSURE; CONTROLLED STUDY; DOSE CALCULATION; DOSE RESPONSE; DRUG EFFECT; EXPERIMENTAL ANIMAL; EXPERIMENTAL MODEL; HEART OUTPUT; LUNG ARTERY PRESSURE; LUNG CAPILLARY PRESSURE; LUNG CIRCULATION; LUNG EMBOLISM; LUNG VASCULAR RESISTANCE; MEAN ARTERIAL PRESSURE; MEASUREMENT; MICROEMBOLISM; NONHUMAN; PULMONARY HYPERTENSION; SWINE; SYSTEMIC VASCULAR RESISTANCE;

ANIMALS; CARDIAC OUTPUT; DOSE-RESPONSE RELATIONSHIP, DRUG; HYPERTENSION, PULMONARY; MAGNESIUM; PROSPECTIVE STUDIES; PULMONARY EMBOLISM; STATISTICS, NONPARAMETRIC; SWINE; VASCULAR RESISTANCE;

EID: 11144291079     PISSN: 03424642     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00134-004-2424-0     Document Type: Article

References (63)

1. Sakuma M, Konno Y, Shirato K (2002) Increasing mortality from pulmonary embolism in Japan, 1951-2000. Circ J 66:1144-1149
2. Lilienfeld DE (2000) Decreasing mortality from pulmonary embolism in the United States, 1979-1996. Int J Epidemiol 29:465-469
3. Laissue JA, Gebbers JO, Musy JP (1984) Pulmonary embolism: epidemiology and pathology. Schweiz Med Wochenschr 114:1711-1720
4. Hansson PO, Welin L, Tibblin G, Eriksson H (1997) Deep vein thrombosis and pulmonary embolism in the general population. 'The study of men born in 1913'. Arch Intern Med 157:1665-1670
5. Bussani R, Cosatti C (1990) Pulmonary embolism: epidemiologic analysis of 27,410 autopsies during a 10-year period. Medicina 10:40-43
6. Goldhaber SZ, Visani L, De Rosa M (1999) Acute pulmonary embolism: clinical outcomes in the international cooperative pulmonary embolism registry (ICOPER). Lancet 353:1386-1389
7. Lignitz E, Lignitz G, Puschel K (1995) Lung embolism as the cause of death in legal medicine. Versicherungsmedizin 47:203-207
8. Vieillard-Baron A, Jardin F (2003) Why protect the right ventricle in patients with acute respiratory distress syndrome? Curr Opin Crit Care 9:15-21
9. British Thoracic Society (2003) Guidelines for the management of suspected acute pulmonary embolism. Thorax 58:470-483
10. Wood KE (2002) Major pulmonary embolism. Chest 121:877-905
11. Comess KA, DeRook FA, Russell ML, Tognazzi-Evans TA, Beach KW (2000) The incidence of pulmonary embolism in unexplained sudden cardiac arrest with pulseless electrical activity. Am J Med 109:351-356
12. Krivec B, Voga G, Zuran I, Skale R, Pareznik R, Podbegar M, Noc M (1997) Diagnosis and treatment of shock due to massive pulmonary embolism. Chest 112:1310-1316
13. Spohr F, Boettiger BW (2003) Thrombolytic therapy during and after cardiopulmonary resuscitation. Efficacy and safety of a new therapeutic approach. Minerva Anestesiol 69:357-364
14. Gei AF, Vadhera RB, Hankins GD (2003) Embolism during pregnancy: thrombus, air and amniotic fluid. Anesthesiol Clin N Am 21:165-182
15. Kucher N, Luder CM, Dornhofer T, Windecker S, Meier B, Hess OM (2003) Novel management strategy for patients with suspected pulmonary embolism. Eur Heart J 24:366-376
16. Hasei M, Inamori N, Hitomi K, Tanigami H, Hirata T, Mori T (2003) Intensive care management of acute pulmonary thromboembolism. Masui 52:14-19
17. Hsieh YY, Chang CC, Li PC (2000) Successful application of extracorporal membrane oxygenation and intraaortic balloon counterpulsation as a lifesaving therapy for a patient with amniotic fluid embolism. Am J Obstet Gynecol 183:496-497
18. Boettiger BW, Motsch J, Doersam J, Mieck U, Gries A, Weimann J, Martin E (1996) Inhaled nitric oxide selectively decreases pulmonary artery pressure and pulmonary vascular resistance following acute massive pulmonary microembolism in piglets. Chest 110:1041-1047
19. Daffa SH, Milaat WA (2002) Role of magnesium sulphate in treatment of severe persistent pulmonary hypertension of the newborn. Saudi Med J 23:1266-1269
20. Lin SC, Teng RJ, Wang JK (1996) Management of severe pulmonary hypertension in an infant with obstructed total anomalous pulmonary venous return using magnesium sulfate. Int J Cardiol 56:131-135
21. Tolsa JF, Cotting J, Sekarski N, Payot M, Micheli JL, Calame A (1995) Magnesium sulphate as an alternative and safe treatment for severe persistent pulmonary hypertension of the newborn. Arch Dis Child 72:F184-F187
22. Haas KM, Suzuki S, Yamaguchi N, Kato I, Ban K, Tanaka T, Fukuda S, Togari H (2002) Nitric oxide further attenuates pulmonary hypertension in magnesium-treated piglets. Pediatr Int 44:670-674
23. National Institutes of Health (1985) Guide for the care and use of laboratory animals (NIH publication No. 85-23). Washington, DC: NIH
24. Shelub I, van Grondelle A, McCullough R, Hofmeister S, Reeves JT (1984) A model of embolic chronic pulmonary hypertension in the dog. J Appl Physiol 56:810-815
25. Weimann J, Zink W, Schnabel PA, Jakob H, Gebhard MM, Martin D, Motsch J (1999). Selective vasodilation by nitric oxide during sustained pulmonary hypertension following recurrent microembolism in pigs. J Crit Care 14:133-140
26. Jones AE, Watts JA, Debelak JP, Thornton LR, Younger JG, Kline J (2003) Inhibition of prostaglandin synthesis during polystyrene microsphere-induced pulmonary embolism in the rat. Am J Physiol Lung Cell Mol Physiol 284:L1072-1081
27. Delcroix M, Melot C, Vachiery JL, Lejeune P, Leeman M, Vanderhoeft P, Naeije R (1990) Effects of embolus size on hemodynamics and gas exchange in canine embolic pulmonary hypertension. J Appl Physiol 69:2254-2261
28. Altura BM, Altura BT (1981) Magnesium ions and contraction of vascular smooth muscles: relationship to some vascular diseases. (FASEB J) Fed Proc 40:2672-2679
29. Belfort MA, Anthony J, Saade GR, Allen JC (2003) A comparison of magnesium sulfate and nimodipine for the prevention of eclampsia. N Engl J Med 348:304-311
30. Fullerton DA, Hahn AR, Agrafojo J, Sheridan BC, McIntyre RC (1996) Magnesium is essential in mechanisms of pulmonary vasomotor control. J Surg Res 63:93-97
31. Villamor E, Ferez-Vizcaino F, Ruiz T, Tamargo J, Moro M (1996) In vitro effects of magnesium sulfate in isolated intrapulmonary and mesenteric arteries of piglets. Pediatr Res 39:1107-1112
32. Connolly E, Worthley LIG (1999) Intravenous magnesium. Crit Care Resuscitation 1:162-172
33. Yoshimura M, Oshima T, Matsuura H, Ishida T, Kambe M, Kajiyama G (1997) Extracellular Mg2+ inhibits capacitative Ca2+ entry in vascular smooth muscle cells. Circulation 95:2567-2572
34. Altura BM, Altura BT (1984) Interactions of Mg and K on blood vessels - aspects in view of hypertension. Review of present status and new findings. Magnesium 3:175-194
35. Watson KV, Moldow CF, Ogburn PL, Jacob HS (1986) Magnesium sulfate: rationale for its use in preeclampsia. Proc Natl Acad Sci USA 83:1075-1078
36. Hirota K, Sato T, Hashimoto Y, Yoshioka H, Ohtomo N, Ishihara H, Matsuki A (1999) Relaxant effect of magnesium and zinc on histamine-induced bronchoconstriction in dogs. Crit Care Med 27:1159-1163
37. Cheng XY, Chen KY, Zhang XH, Zhu PH (2002) Effect of zinc ions on caffeine-induced contracture in vascular smooth muscle and skeletal muscle of rat. Cell Physiol Biochem 12:119-126
38. Sitbon O, Humbert M, Jagot JL, Taravella O, Fartoukh M, Parent F, Herve P, Simonneau G (1998) Inhaled nitric oxide as a screening agent for safely identifying responders to oral calcium-channel blockers in primary pulmonary hypertension. Eur Respir J 12:263-264
39. Rich S, Kaufmann E, Levy PS (1992) The effect of high doses of calcium-channel blockers on survival in primary pulmonary hypertension. N Engl J Med 327:76-81
40. Barst RJ, Maislin G, Fishman AP (1999) Vasodilator therapy for primary pulmonary hypertension in Children. Circulation 99:1197-1208
41. Dickstein PJ, Trinlade O, Goldberg RN, Bancalari E (1984) The effect of calcium antagonists on hypoxic pulmonary hypertension in the piglet. Pediatr Res 18:1262-1265
42. Patole SK, Finer NN (1995) Experimental and clinical effects of magnesium infusion in the treatment of neonatal pulmonary hypertension. Magnes Res 8:373-388
43. Roberts JD, Polaner DM, Lang P, Zapol WM (1992) Inhaled nitric oxide in persistent pulmonary hypertension of the newborn. Lancet 340:818-819
44. Bindl L, Fahnenstrich H, Peukert U (1994) Aerolised prostacyclin for pulmonary hypertension in neonates. Arch Dis Child 71:F214-216
45. Cornfield DN, Maynard RC, deRegnier RA, Guiang SF, Babato F, Milla CE (1999) Randomised controlled trial of low-dose inhaled nitric oxide for the treatment of term and near term infants with respiratory failure and pulmonary hypertension. Pediatrics 104:1089-1094
46. Sadiq HF, Mantych G, Benawra RS, Devaskar UP, Hocker JR (2003) Inhaled nitric oxide in the treatment of moderate pulmonary hypertension of the newborn: a randomised controlled multicenter trial. J Perinatol 23:98-103
47. Davidson D, Barefield ES, Kattwinkel J, Dudell G, Damask M, Strauer R, Rhines J, Chang CT (1998) Inhaled nitric oxide for the early treatment of persistent pulmonary hypertension of the newborn: a randomised double-masked, placebo-controlled, dose-response, multicenter study. The I-NO/ PPHN study group. Pediatrics 101:325-334
48. Abu-Osba YK, Galal O, Manasra K, Rejjal A (1992) Treatment of severe persistent pulmonary hypertension of the newborn with magnesium sulphate. Arch Dis Child 67:31-35
49. Wu TJ, Teng RJ, Yau KIT (1995) Persistent pulmonary hypertension of the newborn treated with magnesium sulfate in premature neonates. Pediatrics 96:472-474
50. Ryan CA, Finer NN, Barrington KJ (1994) Effects of magnesium sulfate and nitric oxide in pulmonary hypertension induced by hypoxia in newborn piglets. Arch Dis Child Fetal Neonat Ed 71:F151-F155
51. Anderson ME, Burnette TM, Geiser DR, Janjindamai W (1994) Magnesium attenuates pulmonary hypertension due to hypoxia and group B streptococci. J Appl Physiol 77:751-756
52. Abu-Osba YK, Rhydderch D, Dalasundaram S, Galal O, Rejjal A, Al Halees Z, Duran C (1990) Reduction of hypoxia induced pulmonary hypertension by MgSO4 in sheep. Pediatr Res 27:351A
53. Cropp GJA (1968) Reduction of hypoxic pulmonary vasoconstriction by magnesium chloride. J Appl Physiol 24:755-760
54. Al-Halees Z, Afrane B, El-Barbary M (1997) Magnesium sulfate to facilitate weaning of nitric oxide in pulmonary hypertension. Ann Thorac Surg 63:298-299
55. Pagnamenta A, Fesler P, Vandinivit A, Brimioulle S, Naeije R (2003) Pulmonary vascular effects of dobutamine in experimental pulmonary hypertension. Crit Care Med 31:1140-1146
56. Bradford KK, Deb B, Pearl RG (2000) Combination therapy with inhaled nitric oxide and intravenous dobutamine during pulmonary hypertension in the rabbit. J Cardiovasc Pharmacol 36:146-151
57. Melot C, Vermeulen F, Maggiorini M, Gilbert E, Naeije R (1997) Site of pulmonary vasodilation by inhaled nitric oxide in microembolic lung injury. Am J Respir Crit Care Med 156:75-85
58. Grattan RM, Zagosrki J, Watts JA, Kline JA (2003) Pulmonary gene expression after experimental pulmonary embolism. Acad Emerg Med 10:576
59. Smulders YM (2001) Contribution of pulmonary vasoconstriction to haemodynamic instability after acute pulmonary embolism. Implications for treatment? Neth J Med 58:241-247
60. Izzo AA, Gagniella TS, Mascolo N, Capasso F (1994) Nitric oxide as a mediator of the laxative action of magnesium sulfate. Br J Pharmacol 113:228-232
61. Gold ME, Buga GM, Wood KS (1990) Antagonistic modulatory role of magnesium and calcium on release of endothelium-derived relaxing factor and smooth muscle tone. Circ Res 66:355-356
62. Schulze-Neick I, Bueltmann M, Werner H, Gamillscheg A, Vogel M, Berger F, Roissant R, Hetzer R, Lange PE (1997) Right ventricular function in patients treated with inhaled nitric oxide after cardiac surgery for congenital heart disease in newborns and children. Am J Cardiol 80:360-363
63. Schulze-Neick I, Uhlemann F, Nürnberg JH, Bültmann M, Haas NA, Dähnert I, Alexi-Meshkisvilli V, Opitz C, Pappert D, Rossaint R, Kleber FX, Hetzer R, Lange PE (1997) Aerolosiertes Prostazyklin zur präoperativen Evaluation und postkardiochirurgischen Behandlung von Patienten mit pulmonaler Hypertension. Z Kardiol 86:71-80