Epitope mapping of Burkholderia pseudomallei serine metalloprotease: Identification of serine protease epitope mimics

FEMS Immunology and Medical Microbiology

Volumn 43, Issue 1, 2005, Pages 37-44

  Chan, Shzu Wei ^a   Nathan, Sheila ^a  

^a Universiti K   (Malaysia)

Author keywords

Burkholderia pseudomallei; Epitope mapping; Molecular modeling; Phage display

Indexed keywords

EPITOPE; GLYCYLTHREONYLSERYLMETHIONYLALANYLTHREONYLPROLYLHISTIDYLVALYLALANYLGLYCINE; IMMUNOGLOBULIN G; METALLOPROTEINASE; NEUTRALIZING ANTIBODY; PEPTIDE; PEPTIDE LIBRARY; POLYCLONAL ANTIBODY; POLYPEPTIDE; SERINE METALLOPROTEASE; SERINE PROTEINASE; THREONYLLYSYLSERYLMETHIONYLALANYLLEUCYLSERYLGLYCINE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANTIGEN BINDING; ARTICLE; BURKHOLDERIA PSEUDOMALLEI; CONFORMATION; CONSENSUS SEQUENCE; CONTROLLED STUDY; ENZYME ACTIVE SITE; EPITOPE MAPPING; MOLECULAR MIMICRY; MOLECULAR MODEL; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN ISOLATION; SEQUENCE ANALYSIS; THREE DIMENSIONAL IMAGING;

AMINO ACID SEQUENCE; ANTIBODIES, BACTERIAL; BINDING SITES; BINDING, COMPETITIVE; BURKHOLDERIA PSEUDOMALLEI; EPITOPE MAPPING; IMMUNOGLOBULIN G; MODELS, MOLECULAR; PEPTIDE LIBRARY; PROTEIN CONFORMATION; SERINE ENDOPEPTIDASES;

EID: 11144276434     PISSN: 09288244     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.femsim.2004.06.025     Document Type: Article

References (25)

1. D.A. Dance Melioidosis: the tip of the iceberg? Clin. Microbiol. Rev. 4 1991 52 60
2. S. Haussler, M. Nimtz, T. Domke, V. Wray, and I. Steinmetz Purification and characterization of a cytotoxic exolipid of Burkholderia pseudomallei Infect. Immun. 66 1998 1588 1593
3. Ismail, G., Mohamed, R. and Embi, M.N. (1994) First International Symposium on Melioidosis. In: Puthucheary, S.D., Malik, Y.A., (Eds.), Melioidosis. Prevailing Problems and Future Directions. Kuala Lumpur, Malaysia, pp. 55-66
4. L.R. Ashdown, and J.M. Koehler Production of hemolysin and other extracellular enzymes by clinical isolates of Pseudomonas pseudomallei J. Clin. Microbiol. 28 1990 2331 2334
5. 2+ for optimal exoprotease production in chemically defined media Appl. Environ. Microbiol. 61 1995 3151 3153
6. M.M. Sexton, A.L. Jones, W. Chaowagul, and D.E. Woods Purification and characterization of a protease from Pseudomonas pseudomallei Can. J. Microbiol. 40 1994 903 910
7. C.R. Corbett, M.N. Burtnick, C. Kooi, D.E. Woods, and P.A. Sokol An extracellular zinc metalloprotease gene of Burkholderia cepacia Microbiology 149 2003 2263 2271
8. M.A. Lee, and Y. Liu Sequencing and characterization of a novel serine metalloprotease from Burkholderia pseudomallei FEMS Microbiol. Lett. 192 2000 67 72
9. E. Valade, F.M. Thibault, Y.P. Gauthier, M. Palencia, M.Y. Popoff, and D.R. Vidal The PmlI-PmlR quorum-sensing system in Burkholderia pseudomallei plays a key role in virulence and modulates production of the MprA protease J. Bacteriol. 186 2004 2288 2294
10. A.G. Amit, R.A. Mariuzza, and S.E.V. Phillips Three-dimensional structure of an antigen-antibody complex at 2.8 Å resolution Science 233 1986 747 753
11. P.M. Colman, W.G. Laver, J.N. Varghese, A.T. Baker, P.A. Tulloch, G.M. Air, and R.G. Webster Three-dimensional structure of a complex of antibody with influenza virus neuraminidase Nature 326 1986 358 363
12. R. Jemmerson, and Y. Patterson Mapping epitopes on a protein antigen by the proteolysis of antigen-antibody complexes BioTechniques 4 1986 18 21
13. Y. Paterson, S.W. Englander, and H. Roder An antibody binding site on cytochrome c defined by hydrogen exchange and two-dimensional NMR Science 249 1990 755 759
14. R. Cortese, F. Felici, G. Galfre, A. Luzzago, P. Monaci, and A. Nicosia Epitope discovery using peptide libraries displayed on phage Trends Biotechnol. 12 1994 262 267
15. F. Felici, A. Luzzago, A. Folgori, and R. Cortese Mimicking of discontinuous epitopes by phage-displayed peptides, II. Selection of clones recognized by a protective monoclonal antibody against the Bordetella pertussis toxin from phage peptide libraries Gene 128 1993 21 27
16. S. Cabilly The basic structure of filamentous phage and its use in the display of combinatorial peptide libraries Mol. Biotechnol. 12 1999 143 148
17. J. Sambrook, E.F. Fritsch, and T. Maniatis Molecular Cloning: A Laboratory Manual second ed. 1989 Cold Spring Harbor Laboratories Press Cold Spring Harbor
18. Chan, S.W., Ong, G.I. and Nathan, S. (2004) Neutralizing chimeric mouse-human antibodies against Burkholderia pseudomallei protease: Expression, purification and characterization. J. Biochem. Mol. Biol. 37(5), in press
19. Ph.D.-12™ Phage Display Peptide Library Kit, New England BioLabs Inc., Instruction Manual, pp. 14
20. J.J. Devlin, L.C. Panganiban, and P.E. Devlin Random peptide libraries: a source of specific protein binding molecules Science 249 1990 404 406
21. J. Novotny, and J. Bajorath Computational biochemistry of antibodies and T-cell receptors Adv. Protein Chem. 49 1996 149 260
22. C. Ebner, Z. Szepfalusi, F. Ferreira, A. Jilek, R. Valenta, P. Parronchi, E. Maggi, S. Romagnani, O. Scheiner, and D. Kraft Identification of multiple T cell epitopes on Bet v I, the major birch pollen allergen, using specific T cell clones and overlapping peptides J. Immunol. 150 1993 1047 1054
23. D. Sesardie Synthetic peptide vaccines J. Med. Microbiol. 39 1993 241 242
24. S. Touji, I. Nomura, S. Giguere, S. Tomomitsu, T. Kakuda, V. Ganne, and S. Takai Immunogenecity of synthetic peptides representing linear B-cell epitopes of VapA of Rhodococcus equi Vaccine 22 2004 1114 1123
25. Sundaram, R., Lynch, m.P., Rawale, S.V., Sun, Y., Kazanji, M. and Kaumaya P.T. (2004) De novo design of peptide immunogens that mimic the coiled-coil region of human T-cell leukemia virus type-1 gp120 transmembrane subunit for induction of native protein reactive neutralizing antibodies. J. Biol. Chem. (E-pub ahead of print)