Peutz-Jeghers syndrome: Case reports and update on diagnosis and treatment

Chinese Journal of Digestive Diseases

Volumn 5, Issue 4, 2004, Pages 160-164

  Dong, Ke ^a   Li, Bo ^a  

^a SICHUAN UNIVERSITY   (China)

Author keywords

Peutz Jeghers syndrome; Polyps; Treatment

Indexed keywords

ABDOMINAL PAIN; ADOLESCENT; ADULT; ANAMNESIS; ANEMIA; ARTICLE; CANCER SUSCEPTIBILITY; CARCINOGENESIS; CLINICAL ARTICLE; COLON CANCER; COLON RESECTION; DISEASE ASSOCIATION; FAMILY HISTORY; FAMILY STUDY; FEMALE; FOLLOW UP; GASTROINTESTINAL ENDOSCOPY; GASTROINTESTINAL RADIOGRAPHY; HEMATOCHEZIA; HISTOPATHOLOGY; HUMAN; INCIDENCE; INTESTINE CARCINOMA; INTESTINE INTUSSUSCEPTION; INTESTINE POLYP; LAPAROTOMY; MALE; MALIGNANT TRANSFORMATION; MEDICAL ASSESSMENT; PANCREAS CANCER; PEUTZ JEGHERS SYNDROME; POLYPECTOMY; PRIORITY JOURNAL; RECURRENT DISEASE; STOMACH CANCER; SYMPTOM; VOMITING;

ADOLESCENT; ADULT; CELL TRANSFORMATION, NEOPLASTIC; FEMALE; HUMANS; INTESTINAL NEOPLASMS; INTESTINAL POLYPS; INTUSSUSCEPTION; MALE; PEDIGREE; PEUTZ-JEGHERS SYNDROME; RECURRENCE;

EID: 11144272570     PISSN: 14439611     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1443-9573.2004.00179.x     Document Type: Article

References (14)

1. Burt RW. Poloypsis syndromes. Clin Perspect Gastroenterol 2002: 51-9.
2. Giardiello FM, Brensinger JD, Tersmette AC. Very high risk of cancer in familial Peutz-Jeghers syndrome. Gastroenterology 2000; 119: 1447-53.
3. Hemminki A, Tomlinson I, Markie D et al. Localization of susceptibility locus for Peutz-jeghers syndrome to 19p using comparative genomic hybridization and targeted linkage analysis. Nat Genet 1997; 15: 87-90.
4. Boardman LA, Couch FJ, Burgart LJ et al. Genetic heterogeneity in Peutz-Jeghers syndrome. Hum Mutat 2000; 16: 23-30.
5. Peutz; JLA. Very remarkable case of familial polyposis of mucous membrane of intestinal tract and nasopharynx accompanied by peculiar pigmentation of skin and mucous membrane. Ned Maandscbr Geneesk 1921; 10: 134-46.
6. Jeghers H, McKusick VA, Katz KH. Generalized intestinal polyposis and melanin spots of the oral mucosa, lip and digits: a syndrome of diagnostic significance. N Engl J Med 1949; 241: 992-1005.
7. Boardman LA, Thibodeau SN, Schaid DJ et al. Increased risk for cancer in patients with the Peutz-Jeghers syndrome. Ann Intern Med 1998; 128: 896-9.
8. Gruber SB, Entius EM, Petersen GM. Pathogenesis of adenocarcinoma in Peutz-Jeghers syndrome. Cancer Res 1998; 58 5267-70.
9. Giardiello FM, Welsh SB, Hamilton SR. et al. Increased risk of cancer in Peutz-Jeghers syndrome. N Engl J Med 1987; 316 1511-14.
10. Foley TR, McGarrity TJ, Abt AB. Peutz-Jeghers syndrome: a clinicopathologic survey of the 'Harrisburg family' with a 49-year follow-up. Gastroenterology 1988; 95: 1535-40.
11. Wang ZJ, Ellis I, Zauber P. Allelic imbalance at the LKB1 (STK11) locus in tumors from patients with Peutz-Jeghers' syndrome provides evidence for a hamartoma-(adenoma)-carcinoma sequence. J Pathol 1999; 188: 9-13.
12. Tovar JA, Eizaguirre I, Albert A, Jimenez J. Peutz-Jeghers syndrome in children: report of two cases and review of the literature. J Pediatr Surg 1983; 18: 1-6.
13. Akiyama Y, Kataoka H, Nabershima K, Koono M. Adenocarcinoma arising in a gastric Peutz-Jeghers polyp. Jpn J Pediatr Surg 2001; 33: 770-4.
14. Suda T, Wataanabe H, Hatakeyama K. Peutz-Jeghers syndrome. Rinsbo Kagaku 1988; 24: 332-40.