In vivo growth-inhibition of S180 tumor by mixture of 5-Fu and low molecular λ-carrageenan from Chondrus ocellatus

Pharmacological Research

Volumn 51, Issue 2, 2005, Pages 153-157

  Zhou, Gefei ^a,b,c   Xin, Hua ^c   Sheng, Wenxu ^d   Sun, Yueping ^c   Li, Zhien ^a   Xu, Zuhong ^a  

^a INSTITUTE OF OCEANOLOGY   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^c QINGDAO AGRICULTURAL UNIVERSITY   (China)

^d Laiyang Health School   (China)

Author keywords

5 Fu; Antitumor; Immunocompetence; Low molecular carrageenan

Indexed keywords

CARRAGEENAN; FLUOROURACIL; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER INHIBITION; CELL LEVEL; CHONDRUS; CONTROLLED STUDY; DRUG EFFECT; DRUG POTENTIATION; HISTOPATHOLOGY; LYMPHOCYTE PROLIFERATION; MOLECULAR WEIGHT; MOUSE; NONHUMAN; ORGAN WEIGHT; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; SPLEEN WEIGHT;

ANIMALS; CARRAGEENAN; CHONDRUS; DRUG THERAPY, COMBINATION; FLUOROURACIL; GROWTH INHIBITORS; MICE; MICE, INBRED ICR; SARCOMA 180;

EID: 11144271352     PISSN: 10436618     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.phrs.2004.07.003     Document Type: Article

References (17)

1. G. Frantz Polysaccharides in pharmacy: current applications and future concepts Planta Medica 55 1989 493 497
2. R. DePhilippis, and M. Vincenzini Exocellular polysaccharides from cyanobacteria and their possible applications FEMS Microbiol Rev 22 1998 151 175
3. K.C. Güven, Y. özsoy, and O.N. Ulutin Anticoagulant fibrinolytic and antiaggregant activity of carrageenans and alginic acid Botanica Marina 34 1991 429 432
4. Z. Quanbin, L. Ning, and Z. Gefei In vivo antioxidant activity of polysaccharide fraction from Porphyra haitanesis (Rhodephyta) in aging mice Pharmacol Res 48 2003 151 155
5. Xu Z, Li Z, Zhang X, Guo Y. Application of Fucodian polysaccharides sulfate as a drug for treating chronic renal failure. CN 98120283. 7, 16 December 1995.
6. F. Jiang, and Y. Zhang The Dictionary of Chinese Oceanic Medicine 1993 Ocean Press
7. C. Parish Pharmacological properties of a marine natural product Biophys Acta 936 1987 55 59
8. D.J. Schaeffer, and V.S. Krylov Anti-HIV activity of extracts and compounds from algae and cyanobacteria Carbohydrate Polym 41 2000 185 190
9. R.L. Tellam, and C.R. Parish R. The effect of sulfated polysaccharides on the free intracellular calcium ion concentration of lymphocytes Biochem et Biophys Acta 930 1987 55 64
10. W. Anderson, and J.G.C. Duncan The anticoagulant activity of carrageenan J Pharm Pharmacol 17 1965 647 654
11. Z. Gefei, S. YuePing, X. Hua, Z. Yuna, L. Zhien, and X. Zuhong In vivo anti-tumor and immunomodulation activities of different molecular weight lambda-carrageenans from Chondrus ocellatus Pharmacol Res 50 1 2004 47 53
12. W. Zhang, and J.F. Zhou The influence of laver Polysaccharide on the growth of immune cells and tumor cells Res Life Sci 6 2002 167 170
13. T. Mosmann Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays J Immunol Meth 65 1983 55 63
14. 13C high resolution NMR spectroscopy of carrageenans: application on research and industry Trend Food Sci Technol 13 2002 73 92
15. I. Shigeaki, H. Tadayoshi, O. Shuzo, and M. Seiji Lymphocyte activation by purified carrageenan J Immunol 125 1980 2232 2235
16. N. Takiguchi, N. Saito, M. Nunomura, K. Kouda, K. Oda, and N. Furuyama Use of 5-FU plus hyperbaric oxygen for treating malignant tumors: evaluation of antitumor effect and measurement of 5-FU in individual organs Cancer Chemother Pharmacol 47 2001 11 14
17. H. Matsuoka, K. Yano, and Y. Seo Usefulness of lymphocyte subset change as an indicator for predicting survival time and effectiveness of treatment with the immunopotentiator lentinan Anticancer Res 15 5B 1995 2291