Proposal for molecular mechanism of thionins deduced from physicochemical studies of plant toxins

Journal of Peptide Research

Volumn 64, Issue 6, 2004, Pages 210-224

  Stec, B ^a   Markman, O ^b,f   Rao, U ^b   Heffront, G ^b,g   Henderson, S ^c,h   Vernon, L P ^d   Brumfeld, V ^e   Teeter, M M ^b  

^a UNIVERSITY OF TEXAS AT EL PASO   (United States)

^b BOSTON COLLEGE   (United States)

^c OAK RIDGE NATIONAL LABORATORY   (United States)

^d Brigham Young University   (United States)

^e WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^f Department of Glycobiology   (Israel)

^g HARVARD MEDICAL SCHOOL   (United States)

^h UNIVERSITY OF COLORADO   (United States)

Author keywords

Mechanism of toxicity; Membrane lysis; Plant toxins; Thionins

Indexed keywords

ALPHA1 PUROTHIONIN; BETA PUROTHIONIN; GLYCEROL; GLYCEROPHOSPHATE; PHOSPHATE; PHOSPHATIDIC ACID; PHOSPHATIDYLSERINE; PHOSPHOLIPID; PLANT TOXIN; THIONINE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CELL DEATH; COMPLEX FORMATION; CRYSTAL STRUCTURE; CYTOPLASM; FLUORESCENCE SPECTROSCOPY; MEMBRANE DAMAGE; MOLECULAR MECHANICS; MOLECULAR MODEL; NONHUMAN; OLIGOMERIZATION; PHOSPHOLIPID MEMBRANE; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE; PHYTOTOXICITY; PRIORITY JOURNAL; PROTEIN LIPID INTERACTION; RADIATION SCATTERING; SOLUBILITY; STRUCTURE ANALYSIS; TOXIN ANALYSIS; TOXIN STRUCTURE; X RAY CRYSTALLOGRAPHY;

ANTIMICROBIAL CATIONIC PEPTIDES; BINDING SITES; CELL MEMBRANE; CRYSTALLOGRAPHY, X-RAY; FLUORESCENCE POLARIZATION; GLYCEROPHOSPHATES; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, CHEMICAL; MODELS, MOLECULAR; PHOSPHOLIPIDS; PLANT PROTEINS; PYRULARIA; SEQUENCE ALIGNMENT; SOLUBILITY; TOXINS, BIOLOGICAL;

EID: 11144268538     PISSN: 1397002X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1399-3011.2004.00187.x     Document Type: Article

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