Human salivary peptides derived from histatins

European Journal of Morphology

Volumn 41, Issue 2, 2003, Pages 99-102

  Lupi, A ^a   Schinina M E ^b   Denotti, G ^c   Fadda, M B ^c   Piras, V ^c   Patamia, M ^a   Cordaro, M ^d   Isola, M ^c   Messana, I ^c  

^a CNR   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

^c UNIVERSITY OF CAGLIARI   (Italy)

^d CATHOLIC UNIVERSITY   (Italy)

Author keywords

Histatins; HPLC ESI MS; Human whole saliva; MALDI TOF MS

Indexed keywords

HISTATIN; HISTATIN 1; HISTATIN 10; HISTATIN 2; HISTATIN 3; HISTATIN 5; HISTATIN 7; HISTATIN 8; LEUCYLTYROSYLASPARTYLASPARAGINE; PEPTIDE; SALIVA PROTEIN; SERYLASPARAGINYLTYROSYLLEUCYLTYROSYLASPARTYLASPARAGINE; TYROSYLLEUCYLTYROSYLASPARTYLASPARAGINE; UNCLASSIFIED DRUG;

ACIDIFICATION; AMINO ACID SEQUENCE; CARBOXY TERMINAL SEQUENCE; CONFERENCE PAPER; FRACTIONATION; GEL CHROMATOGRAPHY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; MASS SPECTROMETRY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DETERMINATION; PROTEIN ISOLATION; QUANTITATIVE ANALYSIS; SALIVA;

AMINO ACID SEQUENCE; CHROMATOGRAPHY, GEL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HUMANS; PEPTIDES; PROTEINS; SALIVARY PROTEINS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

EID: 11144232372     PISSN: 09243860     EISSN: None     Source Type: Journal    
DOI: 10.1080/09243860412331282200     Document Type: Conference Paper

References (13)

1. Azen EA (1972): Genetic polymorphism of basic proteins from parotid saliva. Science 176: 673-674.
2. Bonilla CA (1969): Rapid isolation of basic proteins and polypeptides from salivary gland secretions by chromatography on polyacrylamide gel. Anal Biochem 32: 522-529.
3. Castagnola M, Congiu D, Denotti G, Di Nunzio A, Fadda MB, Melis S, Messana I, Misiti F, Murtas R, Olianas A, Piras V, Pittau A, Puddu G (2001): Determination of the human salivary peptides histatins 1, 3, 5 and statherin by high-performance liquid chromatography and by diode-array detection. J Chromatogr B 751: 153-160.
4. Chan M, Bennick A (2002): Proteolytic processing of a human salivary proline-rich protein precursor by proprotein convertases. Eur J Biochem 268: 3423-3431.
5. Oppenheim FG, Xu T, McMillian FM, Levitz SM, Diamond RD, Offner GD, Troxler RF (1988): Histatins, a novel family of histidine-rich proteins in human parotid secretion. J Biol Chem 263: 7472-7477.
6. Perinpanayagam HER, Van Wuyckyuse BC, Ji ZS, Tabak LA (1995): Characterisation of low-molecular-weight peptides in human parotid saliva. J Dent Res 74: 345-350.
7. Pollock JJ, Denepitiya L, MacKay BJ, Iacono VJ (1984): Fungistatic and fungicidal activity of human parotid salivary histidine-rich polypeptides on Candida albicans. Infect Immunol 44: 702-707.
8. Sabatini LM, Azen EA (1989): Histatins, a family of salivary histidine-rich proteins, are encoded by at least two loci (HIS1 and HIS2). Biochem Biophys Res Commun 160: 495-502.
9. Sabatini LM, Ota T, Azen EA (1993): Nucleotide sequence analysis of the human salivary protein genes HIS1 and HIS2, and evolution of the STATH/HIS gene family. Mol Biol Evol 10: 491-511.
10. Troxler RF, Offner GD, Xu T, Vanderspek JC, Oppenheim FG (1990): Structural relationship between human salivary histatins. J Dent Res 69: 2-6.
11. Van der Spek JC, Offner GD, Troxler RF, Oppenheim FG (1990): Molecular cloning of human submandibular histatins. Arch Oral Biol 35: 137-143.
12. Xu L, Lal K, Pollock JJ (1992): Histatins 2 and 4 are autoproteolytic degradation products of human parotid saliva. Oral Microbiol Immunol 7: 127-128.
13. Xu L, Lal K, Santarpia R, Pollock JJ (1993): Salivary proteolysis of histidine-rich polypeptides and the antifungal activity of peptide degradation products. Arch Oral Biol 38: 277-283.