Candida rugosa lipase mediated multigram synthesis of acid part of S(+)-atliprofen, a new NSAID and molecular modeling studies aimed at predicting selectivity of the enzyme

Enzyme and Microbial Technology

Volumn 36, Issue 2-3, 2005, Pages 232-238

  Mittal, Shilpi ^a   Khanna, Smriti ^a   Roy, Animesh ^a   Bharatam, Prasad V ^a   Chawla, H P S ^a  

^a P   (India)

Author keywords

Candida rugosa; Enzymatic hydrolysis; Lipase; Molecular modeling; S(+) atliprofen

Indexed keywords

CANDIDA RUGOSA LIPASE; KETOPROFEN; MOLECULAR MODELING; MULTIGRAM SYNTHESIS;

ACETIC ACID; ENZYME INHIBITION; ESTERS; HYDROLYSIS; MATHEMATICAL MODELS; MOLECULAR DYNAMICS; SYNTHESIS (CHEMICAL);

ENZYMES;

4 (3 THIENYL)PHENYL ALPHA METHYLACETIC ACID; ATLIPROFEN; ESTER DERIVATIVE; KETOPROFEN; NAPROXEN; NONSTEROID ANTIINFLAMMATORY AGENT; PROPIONIC ACID DERIVATIVE; PROSTAGLANDIN SYNTHASE INHIBITOR; TRIACYLGLYCEROL LIPASE; UNCLASSIFIED DRUG;

ARTICLE; CANDIDA RUGOSA; CHEMICAL PROCEDURES; DRUG SELECTIVITY; ENANTIOSELECTIVITY; ENZYME SUBSTRATE; HYDROLYSIS; MOLECULAR MODEL; OBSERVATION; PREDICTION;

CANDIDA RUGOSA;

EID: 11044232393     PISSN: 01410229     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.enzmictec.2004.07.012     Document Type: Article

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